Stimulus‐secretion coupling in rat pancreas: role of sodium, calcium and cyclic nucleotides studied by X‐537A and BrX‐537A.

PROTEIN MEASUREMENT WITH THE FOLIN PHENOL REAGENT

1951 • 319,299 citations

Measurement of Low Energy Beta-Emitters in Aqueous Solution by Liquid Scintillation Counting of Emulsions.

1965 • 1,475 citations

Femtomole sensitive radioimmunoassay for cyclic AMP and cyclic GMP after 2'0 acetylation by acetic anhydride in aqueous solution.

1975 • 932 citations

Calcium Ionophores and Movement of Calcium Ions following the Physiological Stimulus to a Secretory Process

1973 • 631 citations

The Importance of Calcium Ions for the Regulation of Guanosine 3′:5′-Cyclic Monophosphate Levels

1973 • 276 citations

Factors controlling cytoplasmic Ca ²⁺ concentration

1973 • 261 citations

Calcium-Induced Extrusion of Secretory Granules (Exocytosis) in Mast Cells Exposed to 48/80 or the Ionophores A-23187 and X-537A

1974 • 253 citations

Properties of ionophores with broad range cation selectivity.

1973 • 244 citations

The relationship between calcium exchange and enzyme secretion in the isolated rat pancreas

1973 • 229 citations

The Effect of Calcium Ionophores on Fragmented Sarcoplasmic Reticulum

1972 • 215 citations

Bioelectric Responses of the Echinoderm Egg to Fertilization

1971 • 199 citations

Regulation of amylase release from dispersed pancreatic acinar cells.

1977 • 192 citations

Pancreatic acinar cells: acetylcholine‐induced membrane depolarization, calcium efflux and amylase release

1973 • 186 citations

Insulin secretion. Interrelationships of glucose, cyclic adenosine 3:5-monophosphate, and calcium.

1975 • 171 citations

The activation of sea urchin eggs by the divalent ionophores A23187 and X-537A

1974 • 163 citations

Pancreatic acinar cells: the role of calcium in stimulus‐secretion coupling.

1976 • 155 citations

Action of cholecystokinin, cholinergic agents, and A-23187 on accumulation of guanosine 3':5'-monophosphate in dispersed guinea pig pancreatic acinar cells.

1976 • 142 citations

Calcium ion uptake in isolated pancreas cells induced by secretagogues

1976 • 121 citations

Induction of Enzyme Secretion in Rat Pancreatic Slices Using the Ionophore A-23187 and Calcium

1974 • 106 citations

Effects of antibiotic lonophore, A23187, on oxidative phosphorylation and calcium transport of liver mitochondria

1973 • 96 citations

Pancreatic acinar cells: ionic dependence of acetylcholine‐induced membrane potential and resistance change.

1975 • 96 citations

Secretion of hydrolases by perfused fragments of rat pancreas: effect of calcium

1971 • 95 citations

Pancreatic acinar cells: Use of a Ca++ ionophore to separate enzyme release from the earlier steps in stimulus-secretion coupling

1974 • 90 citations

Amylase secretion by the perfused cat pancreas in relation to the secretion of calcium and other electrolytes and as influenced by the extrenal ionic environment*

1973 • 88 citations

The role of calcium and cyclic nucleotides in α-amylase release from slices of rat parotid: Studies with the divalent cation ionophore A-23187

1975 • 86 citations

Mechanism of release of norepinephrine from peripheral adrenergic neurones by the calcium ionophores X 537A and A 23187

1974 • 83 citations

A calcium ionophore stimulating the secretion of catecholamines from the cat adrenal.

1975 • 80 citations

Cellular cyclic nucleotides and enzyme secretion in the pancreatic acinar cell.

1976 • 77 citations

Energy sources for protein synthesis and enzymatic secretion in rat pancreas in vitro

1969 • 75 citations

Calcium and stimulus‐secretion coupling in the adrenal medulla: contrasting stimulating effects of the ionophores X‐537A and A23187 on catecholamine output.

1975 • 75 citations

The relationship between the transport of glucose and cations across cell membranes in isolated tissues

1969 • 70 citations

Effects of the lonophore A23187 on the blood platelets II. Influence on ultrastructure.

1974 • 67 citations

Hormone-Induced Cyclic Guanosine Monophosphate Secretion from Guinea Pig Pancreatic Lobules

1977 • 67 citations

A study of calcium binding and uptake by isolated cardiac sarcoplasmic reticulum: The use of a new ionophore (X537A)

1972 • 66 citations

The role of calcium in regulation of cyclic nucleotide content in human umbilical artery.

1975 • 66 citations

Effects of ions on amylase release by dissociated pancreatic acinar cells

1976 • 59 citations

Properties of the guanylate cyclase-guanosine 3':5'-monophosphate system of rat renal cortex. Activation of guanylate cyclase and calcium-independent modulation of tissue guanosine 3':5'-monophosphate by sodium azide.

1976 • 56 citations

Intracellular messenger role of cyclic GMP in exocrine pancreas

1976 • 56 citations

Ca++ fluxes in isolated cells of rat pancreas. Effect of secretagogues and different Ca++ concentrations

1976 • 54 citations

Role of calcium in exocrine pancreatic secretion. II.Comparison of the effects of carbachol and the ionophore A-23187 on enzyme secretion and calcium movements in rabbit pancreas

1976 • 52 citations

Mode of action of the antibiotic X-537A on mitochondrial glutamate oxidation

1973 • 22 citations

Effects of parathyroid hormone on cyclic AMP, cyclic GMP, and efflux of calcium in isolated renal tubules.

1977 • 19 citations

Calcium and cyclic nucleotide interaction in secretion of amylase from rat pancreas in vitro.

1979 • 19 citations

Calcium and cyclic nucleotide involvement in exocrine pancreatic enzyme secretion studied with the ionophore A-23187

1976 • 18 citations

Effects of calcium and chelating agents on the ability of various agonists to increase cyclic GMP in pancreatic acinar cells

1978 • 17 citations

New calcium-mobilising agent

1975 • 17 citations

Dissociation of cyclic GMP synthesis from cholinergic-stimulated secretion of protein from rat exocrine pancreas

1978 • 14 citations

Uncoupling of photophosphorylation in spinach chloroplasts by the ionophorous antibiotic A23187

1974 • 11 citations

THE EFFECT OF DIBUTYRYL CYCLIC ADENOSINE-3′,5′-MONOPHOSPHATE ON PROTEIN SECRETION FROM THE RAT EXOCRINE PANCREAS in vitro

1976 • 9 citations