Sensitization to the rewarding effects of the specific dopamine uptake inhibitor GBR12783.

The neural basis of drug craving: An incentive-sensitization theory of addiction

1993 • 7,074 citations

Drugs abused by humans preferentially increase synaptic dopamine concentrations in the mesolimbic system of freely moving rats.

1988 • 4,617 citations

Cocaine Receptors on Dopamine Transporters Are Related to Self-Administration of Cocaine

1987 • 2,189 citations

Enduring changes in brain and behavior produced by chronic amphetamine administration: A review and evaluation of animal models of amphetamine psychosis

1986 • 2,110 citations

Drugs of abuse: anatomy, pharmacology and function of reward pathways

1992 • 2,091 citations

Dopamine transmission in the initiation and expression of drug- and stress-induced sensitization of motor activity

1991 • 2,025 citations

Stereotypies: a critical review

1991 • 1,247 citations

Thigmotaxis as an index of anxiety in mice. Influence of dopaminergic transmissions

1994 • 701 citations

Stress- and pharmacologically-induced behavioral sensitization increases vulnerability to acquisition of amphetamine self-administration

1990 • 574 citations

Repeated exposures intensify rather than diminish the rewarding effects of amphetamine, morphine, and cocaine

1989 • 480 citations

Time course of transient behavioral depression and persistent behavioral sensitization in relation to regional brain monoamine concentrations during amphetamine withdrawal in rats

1991 • 441 citations

Increasing effects of repetitive cocaine administration in the rat

1976 • 437 citations

Neurobiology of cocaine abuse

1992 • 350 citations

Preexposure to amphetamine and nicotine predisposes rats to self-administer a low dose of cocaine

1992 • 347 citations

Structural requirements for cocaine congeners to interact with dopamine and serotonin uptake sites in mouse brain and to induce stereotyped behavior

1986 • 289 citations

Preexposure sensitizes rats to the rewarding effects of cocaine

1990 • 273 citations

Sensitization to the conditioned rewarding effects of cocaine: pharmacological and temporal characteristics.

1995 • 263 citations

Amphetamine administered to the ventral tegmental area but not to the nucleus accumbens sensitizes rats to systemic morphine: lack of conditioned effects

1990 • 251 citations

Sensitization to the conditioned rewarding effects of morphine: pharmacology and temporal characteristics

1996 • 195 citations

The use of place conditioning in studying the neuropharmacology of drug reinforcement

1989 • 193 citations

Serotonergic mechanisms involved in the discriminative stimulus, reinforcing and subjective effects of cocaine

1997 • 191 citations

Sensitization to repeated morphine injection in the rat: possible involvement of A10 dopamine neurons.

1987 • 176 citations

A subset of ventral tegmental area neurons is inhibited by dopamine, 5-hydroxytryptamine and opioids

1997 • 162 citations

ChemInform Abstract: ARYL 1,4‐DIALK(EN)YLPIPERAZINES AS SELECTIVE AND VERY POTENT INHIBITORS OF DOPAMINE UPTAKE

1981 • 150 citations

Anxiogenic effects of acute and chronic cocaine administration: Neurochemical and behavioral studies

1992 • 144 citations

Involvement of the dorsal raphe but not median raphe nucleus in morphine-induced increases in serotonin release in the rat forebrain

1995 • 133 citations

Role of repeated exposure to morphine in determining its affective properties: place and taste conditioning studies in rats

1991 • 129 citations

The role of 5-HT3 receptors in drug dependence

1995 • 112 citations

GBR 12783, a potent and selective inhibitor of dopamine uptake: Biochemical studies in vivo and ex vivo

1986 • 106 citations

Anxiogenic properties of cocaine in the rat evaluated with the elevated plus-maze

1992 • 102 citations

Modulation of drug-induced sensitization processes by endogenous opioid systems

1995 • 101 citations

Differential reinforcing effects of cocaine and GBR-12909: biochemical evidence for divergent neuroadaptive changes in the mesolimbic dopaminergic system.

1996 • 79 citations

Anxiogenic-like effects induced by stimulation of dopamine receptors

1993 • 66 citations

Evidence for opiate-dopamine cross-sensitization in nucleus accumbens: Studies of conditioned reward

1992 • 63 citations

Cocaine: comparative effect on dopamine uptake in extrapyramidal and limbic systems

1983 • 61 citations

Sensitization of the Locomotor Response to Psychostimulants after Repeated Opiate Exposure: Role of the Nucleus Accumbens

1997 • 58 citations

Indirect serotonergic agonists attenuate neuronal opiate withdrawal

1993 • 52 citations

The neurochemistry of morphine addiction in the neocortex

1996 • 40 citations

Locomotor sensitization and decrease in [3H]mazindol binding to the dopamine transporter in the nucleus accumbens are delayed after chronic treatments by GBR12783 or cocaine.

1996 • 38 citations

Mu-Opioid receptors modulate noradrenaline release from the rat hippocampus as measured by brain microdialysis

1994 • 35 citations

Changes in Locomotor Activity, Core Temperature, and Heart Rate in Response to Repeated Cocaine Administration

1996 • 35 citations

Possible novel pharmacodynamic action of cocaine: Cardiovascular and behavioral evidence

1996 • 31 citations

Cocaine's colocalized effects on synaptic serotonin and dopamine in ventral tegmentum in a reinforcement paradigm

1992 • 30 citations

Comparison of the effects of three indirect dopamine agonists, GK 13, GBR 12783 and dexamphetamine on behavioural tests involving central catecholaminergic transmissions

1990 • 29 citations

Effects of drug history on the acquisition of responding maintained by GBR 12909 in rhesus monkeys

1996 • 27 citations

Place conditioning with cocaine and the dopamine uptake inhibitor GBR12783

1996 • 27 citations

Place conditioning with d-amphetamine: The effect of the CS-UCS interval and evidence of a place avoidance

1990 • 26 citations

Discriminative stimulus properties of cocaine: enhancement by ββ-adrenergic receptor antagonists

1997 • 21 citations

In vivo labelling of the neuronal dopamine uptake complex in the mouse striatum by [3H]GBR 12783

1992 • 19 citations

Pipradrol conditioned place preference is blocked by SCH23390

1992 • 16 citations

Cocaine Effects on Dopamine and Opioid Peptide Neural Systems: Implications for Human Cocaine Abuse

1996 • 11 citations

Subchronic morphine increases amphetamine-induced potentiation of brain stimulation reward: reversal by DNQX

1995 • 8 citations