Priming of human monocytes for enhanced lipopolysaccharide responses: expression of alpha interferon, interferon regulatory factors, and tumor necrosis factor

Single-Step Method of RNA Isolation by Acid Guanidinium Thiocyanate–Phenol–Chloroform Extraction

1987 • 64,270 citations

A conserved AU sequence from the 3′ untranslated region of GM-CSF mRNA mediates selective mRNA degradation

1986 • 4,200 citations

Identification of a common nucleotide sequence in the 3'-untranslated region of mRNA molecules specifying inflammatory mediators.

1986 • 1,591 citations

There is more than one interleukin 1

1986 • 1,226 citations

Structurally similar but functionally distinct factors, IRF-1 and IRF-2, bind to the same regulatory elements of IFN and IFN-inducible genes

1989 • 970 citations

Interferons and other regulatory cytokines

1988 • 429 citations

Detection of endotoxin in human blood and demonstration of an inhibitor.

1970 • 425 citations

Macrophage growth factor CSF-1 stimulates human monocyte production of interferon, tumor necrosis factor, and colony stimulating activity.

1986 • 397 citations

Absence of the type I IFN system in EC cells: Transcriptional activator (IRF-1) and repressor (IRF-2) genes are developmentally regulated

1990 • 377 citations

Induction of endogenous IFN-α and IFN-β genes by a regulatory transcription factor, IRF-1

1989 • 368 citations

Differential regulation of human monocyte programmed cell death (apoptosis) by chemotactic factors and pro-inflammatory cytokines.

1991 • 294 citations

Induction of the transcription factor IRF-1 and interferon-beta mRNAs by cytokines and activators of second-messenger pathways.

1989 • 292 citations

Polyamines Differentially Modulate the Transcription of Growth-associated Genes in Human Colon Carcinoma Cells

1989 • 211 citations

Differential expression of human interferon genes

1984 • 184 citations

Inhibition of protein synthesis stimulates the transcription of human beta-interferon genes in Chinese hamster ovary cells.

1984 • 128 citations

Tumor necrosis factor production by human monocytes is a regulated event: induction of TNF-alpha-mediated cellular cytotoxicity by endotoxin.

1986 • 105 citations

Sequence discrimination by alternatively spliced isoforms of a DNA binding zinc finger domain

1992 • 98 citations

Multiple Zinc Finger Forms Resulting from Developmentally Regulated Alternative Splicing of a Transcription Factor Gene

1992 • 94 citations

Sequential expression of functions during macrophage differentiation in murine bone marrow liquid cultures

1980 • 90 citations

Differential effect of monoclonal anti-DR antibody on monocytes in antigen- and mitogen-stimulated responses: Mechanism of inhibition and relationship to interleukin 1 secretion

1983 • 65 citations

Production of interferon by in vitro derived bone marrow macrophages

1981 • 60 citations

Production of human lymphoblastoid interferon by Namalva cells

1978 • 58 citations

The 5′-flanking region of a human IFN-α gene mediates viral induction of transcription

1983 • 53 citations

Endogenous interferon production by endotoxin-responsive macrophages provides an autostimulatory differentiation signal

1984 • 53 citations

Regulation of Interferon Production by Human Monocytes: Requirements for Priming for Lipopolysaccharide-Induced Production

1991 • 51 citations

Endotoxin-induced interferon synthesis in macrophage cultures.

1983 • 44 citations

Interferon induction in marrow‐derived macrophages: Regulation by L cell conditioned medium

1981 • 40 citations

Selective neutralization by antiinterferon globulin of macrophage activation by L-cell interferon, Brucella abortus ether extract, Salmonella typhimurium lipopolysaccharide, and polyanions

1979 • 38 citations

Lipopolysaccharide and polyribonucleotide activation of macrophages: Implications for a natural triggering signal in tumor cell killing

1985 • 32 citations

Superinduction of the human interferon-beta promoter.

1987 • 30 citations

Differential Regulation of Interferon Synthesis in Lymphoblastoid Cells

1985 • 14 citations