Default-mode brain dysfunction in mental disorders: A systematic review

A default mode of brain function

2001 • 11,745 citations

Functional connectivity in the motor cortex of resting human brain using echo‐planar mri

1995 • 9,444 citations

The human brain is intrinsically organized into dynamic, anticorrelated functional networks

2005 • 8,267 citations

Spontaneous fluctuations in brain activity observed with functional magnetic resonance imaging

2007 • 6,463 citations

Functional connectivity in the resting brain: A network analysis of the default mode hypothesis

2002 • 6,223 citations

Neuronal Oscillations in Cortical Networks

2004 • 5,947 citations

Consistent resting-state networks across healthy subjects

2006 • 4,239 citations

Measuring phase synchrony in brain signals

1999 • 3,548 citations

Default-mode network activity distinguishes Alzheimer's disease from healthy aging: Evidence from functional MRI

2004 • 3,544 citations

Dynamic predictions: Oscillations and synchrony in top–down processing

2001 • 3,409 citations

Investigations into resting-state connectivity using independent component analysis

2005 • 3,332 citations

Medial prefrontal cortex and self-referential mental activity: Relation to a default mode of brain function

2001 • 2,939 citations

Wandering Minds: The Default Network and Stimulus-Independent Thought

2007 • 2,701 citations

Efficiency and Cost of Economical Brain Functional Networks

2007 • 2,369 citations

Functional and effective connectivity in neuroimaging: A synthesis

1994 • 2,351 citations

Altered baseline brain activity in children with ADHD revealed by resting-state functional MRI

2006 • 2,340 citations

Regional homogeneity approach to fMRI data analysis

2004 • 2,271 citations

Resting-State Functional Connectivity in Major Depression: Abnormally Increased Contributions from Subgenual Cingulate Cortex and Thalamus

2007 • 2,153 citations

Resting-State Functional Connectivity Reflects Structural Connectivity in the Default Mode Network

2008 • 2,147 citations

Spontaneous neuronal activity distinguishes human dorsal and ventral attention systems

2006 • 2,045 citations

Molecular, Structural, and Functional Characterization of Alzheimer's Disease: Evidence for a Relationship between Default Activity, Amyloid, and Memory

2005 • 1,993 citations

Analysis of fMRI data by blind separation into independent spatial components

1998 • 1,900 citations

Electrophysiological signatures of resting state networks in the human brain

2007 • 1,881 citations

An improved approach to detection of amplitude of low-frequency fluctuation (ALFF) for resting-state fMRI: Fractional ALFF

2008 • 1,837 citations

Network structure of cerebral cortex shapes functional connectivity on multiple time scales

2007 • 1,720 citations

The social brain in adolescence

2008 • 1,713 citations

Dynamic Brain Sources of Visual Evoked Responses

2002 • 1,610 citations

Disruption of Large-Scale Brain Systems in Advanced Aging

2007 • 1,563 citations

BRAIN WORK AND BRAIN IMAGING

2006 • 1,554 citations

The neural bases of momentary lapses in attention

2006 • 1,541 citations

Mining event-related brain dynamics

2004 • 1,411 citations

Spontaneous low‐frequency BOLD signal fluctuations: An fMRI investigation of the resting‐state default mode of brain function hypothesis

2005 • 1,368 citations

Separating respiratory-variation-related fluctuations from neuronal-activity-related fluctuations in fMRI

2006 • 1,350 citations

Removal of eye activity artifacts from visual event-related potentials in normal and clinical subjects

2000 • 1,289 citations

The maturing architecture of the brain's default network

2008 • 1,282 citations

Competition between functional brain networks mediates behavioral variability

2007 • 1,267 citations

Reduced resting-state brain activity in the “default network” in normal aging

2007 • 1,133 citations

Functional connectivity of default mode network components: Correlation, anticorrelation, and causality

2008 • 1,097 citations

Aberrant “Default Mode” Functional Connectivity in Schizophrenia

2007 • 1,053 citations

Trial-by-Trial Coupling of Concurrent Electroencephalogram and Functional Magnetic Resonance Imaging Identifies the Dynamics of Performance Monitoring

2005 • 1,041 citations

EEG-correlated fMRI of human alpha activity

2003 • 1,000 citations

Electroencephalographic signatures of attentional and cognitive default modes in spontaneous brain activity fluctuations at rest

2003 • 987 citations

A method for functional network connectivity among spatially independent resting-state components in schizophrenia

2007 • 953 citations

Brain Connectivity Related to Working Memory Performance

2006 • 844 citations

Cingulate-Precuneus Interactions: A New Locus of Dysfunction in Adult Attention-Deficit/Hyperactivity Disorder

2007 • 838 citations

Spontaneous attentional fluctuations in impaired states and pathological conditions: A neurobiological hypothesis

2007 • 828 citations

Changes in hippocampal connectivity in the early stages of Alzheimer's disease: Evidence from resting state fMRI

2006 • 824 citations

Beyond Feeling: Chronic Pain Hurts the Brain, Disrupting the Default-Mode Network Dynamics

2008 • 788 citations

Independent component approach to the analysis of EEG and MEG recordings

2000 • 769 citations

Altered resting state networks in mild cognitive impairment and mild Alzheimer's disease: An fMRI study

2005 • 731 citations

The retrosplenial cortex and emotion: new insights from functional neuroimaging of the human brain

1999 • 731 citations

Appraising the brain's energy budget

2002 • 727 citations

Default-Mode Activity during a Passive Sensory Task: Uncoupled from Deactivation but Impacting Activation

2004 • 702 citations

Resting-state networks in the infant brain

2007 • 682 citations

Coherent spontaneous activity accounts for trial-to-trial variability in human evoked brain responses

2005 • 670 citations

How default is the default mode of brain function?

2006 • 605 citations

Minds at rest? Social cognition as the default mode of cognizing and its putative relationship to the “default system” of the brain

2008 • 604 citations

Functional connectivity in a baseline resting-state network in autism

2006 • 597 citations

Modulation of temporally coherent brain networks estimated using ICA at rest and during cognitive tasks

2008 • 572 citations

Low frequency BOLD fluctuations during resting wakefulness and light sleep: A simultaneous EEG‐fMRI study

2007 • 571 citations

Spontaneous Low-Frequency Fluctuations in the BOLD Signal in Schizophrenic Patients: Anomalies in the Default Network

2007 • 562 citations

Failing to deactivate: Resting functional abnormalities in autism

2006 • 537 citations

Varieties of Attention-Deficit/Hyperactivity Disorder-Related Intra-Individual Variability

2005 • 526 citations

Persistent default‐mode network connectivity during light sedation

2008 • 524 citations

Regional coherence changes in the early stages of Alzheimer’s disease: A combined structural and resting-state functional MRI study

2007 • 510 citations

Infraslow oscillations modulate excitability and interictal epileptic activity in the human cortex during sleep

2004 • 493 citations

Neuronal oscillations and visual amplification of speech

2008 • 493 citations

The intrinsic functional organization of the brain is altered in autism

2007 • 483 citations

Prediction of human errors by maladaptive changes in event-related brain networks

2008 • 471 citations

Going AWOL in the Brain: Mind Wandering Reduces Cortical Analysis of External Events

2007 • 466 citations

Independent component analysis for biomedical signals

2004 • 463 citations

Fourier-, Hilbert- and wavelet-based signal analysis: are they really different approaches?

2004 • 461 citations

Interrupting the “stream of consciousness”: An fMRI investigation

2005 • 436 citations

Network homogeneity reveals decreased integrity of default-mode network in ADHD

2007 • 433 citations

Single-trial EEG–fMRI reveals the dynamics of cognitive function

2006 • 420 citations

Synchronized delta oscillations correlate with the resting-state functional MRI signal

2007 • 417 citations

Functional disintegration in paranoid schizophrenia using resting-state fMRI

2007 • 417 citations

Altered resting-state functional connectivity patterns of anterior cingulate cortex in adolescents with attention deficit hyperactivity disorder

2006 • 401 citations

Widespread functional disconnectivity in schizophrenia with resting-state functional magnetic resonance imaging

2006 • 400 citations

Intra-Subject Variability in Attention-Deficit Hyperactivity Disorder

2006 • 399 citations

Frontal theta EEG activity correlates negatively with the default mode network in resting state

2007 • 392 citations

Where the BOLD signal goes when alpha EEG leaves

2006 • 386 citations

GABA concentrations in the human anterior cingulate cortex predict negative BOLD responses in fMRI

2007 • 348 citations

Research Review: Dopamine transfer deficit: a neurobiological theory of altered reinforcement mechanisms in ADHD

2008 • 329 citations

Temporal lobe interictal epileptic discharges affect cerebral activity in “default mode” brain regions

2006 • 317 citations

Magnetoencephalographic evaluation of resting-state functional connectivity in Alzheimer's disease

2006 • 316 citations

Failure to deactivate in the prefrontal cortex in schizophrenia: dysfunction of the default mode network?

2008 • 309 citations

Altered resting-state functional connectivity and anatomical connectivity of hippocampus in schizophrenia

2008 • 309 citations

Transient and linearly graded deactivation of the human default-mode network by a visual detection task

2008 • 304 citations

On the relationship of synaptic activity to macroscopic measurements: does co-registration of EEG with fMRI make sense?

2000 • 300 citations

Source separation using single channel ICA

2007 • 295 citations

The effect of respiration variations on independent component analysis results of resting state functional connectivity

2008 • 289 citations

Beyond Superior Temporal Cortex: Intersubject Correlations in Narrative Speech Comprehension

2007 • 285 citations

Emotion-induced changes in human medial prefrontal cortex: I. During cognitive task performance

2001 • 282 citations

Abnormal neural activity in children with attention deficit hyperactivity disorder: a resting-state functional magnetic resonance imaging study

2006 • 266 citations

Multiple Sclerosis: Low-Frequency Temporal Blood Oxygen Level–Dependent Fluctuations Indicate Reduced Functional Connectivity—Initial Results

2002 • 256 citations

Natural logarithmic relationship between brain oscillators

2003 • 247 citations

Regional homogeneity, functional connectivity and imaging markers of Alzheimer's disease: A review of resting-state fMRI studies

2008 • 241 citations

Decreased regional homogeneity in schizophrenia: a resting state functional magnetic resonance imaging study

2005 • 240 citations

EEG default mode network in the human brain: Spectral regional field powers

2008 • 238 citations

Attention, Researchers! It Is Time to Take a Look at the Real World

2003 • 238 citations

Fisher discriminative analysis of resting-state brain function for attention-deficit/hyperactivity disorder

2007 • 237 citations

Independent component model of the default-mode brain function: Assessing the impact of active thinking

2006 • 236 citations

Default-mode network activity distinguishes amnestic type mild cognitive impairment from healthy aging: A combined structural and resting-state functional MRI study

2008 • 229 citations

Intrinsic brain activity sets the stage for expression of motivated behavior

2005 • 228 citations

Default mode network connectivity: effects of age, sex, and analytic approach

2008 • 227 citations

Independent Component Analysis for Identification of Artifacts in Magnetoencephalographic Recordings

1997 • 223 citations

A simple view of the brain through a frequency-specific functional connectivity measure

2007 • 220 citations

Altered default mode network activity in patient with anxiety disorders: An fMRI study

2007 • 208 citations

Comment on "Wandering Minds: The Default Network and Stimulus-Independent Thought"

2007 • 207 citations

Nicotine Enhances Visuospatial Attention by Deactivating Areas of the Resting Brain Default Network

2007 • 201 citations

A comparison of resting-state brain activity in humans and chimpanzees

2007 • 200 citations

Resting state oscillatory brain dynamics in Parkinson’s disease: An MEG study

2006 • 196 citations

Endogenous brain oscillations and related networks detected by surface EEG‐combined fMRI

2008 • 187 citations

Individual differences in EEG theta and alpha dynamics during working memory correlate with fMRI responses across subjects

2007 • 179 citations

Increased cortico-cortical functional connectivity in early-stage Parkinson's disease: An MEG study

2008 • 173 citations

Dopaminergic drug effects on physiological connectivity in a human cortico-striato-thalamic system

2003 • 167 citations

Default mode network as revealed with multiple methods for resting-state functional MRI analysis

2008 • 155 citations

Reduced functional brain activity response in cognitively intact apolipoprotein E ε4 carriers

2006 • 150 citations

Default-mode function and task-induced deactivation have overlapping brain substrates in children

2008 • 144 citations

Cognitive Ethology and exploring attention in real-world scenes

2006 • 137 citations

Frontostriatal deficits in fragile X syndrome: Relation to FMR1 gene expression

2004 • 127 citations

Are Anticorrelated Networks in the Brain Relevant to Schizophrenia?

2007 • 122 citations

Social cognitive neural networks during in-group and out-group interactions

2008 • 101 citations

On the relationship between slow cortical potentials and BOLD signal changes in humans

2007 • 99 citations

Linking Hemodynamic and Electrophysiological Measures of Brain Activity: Evidence from Functional MRI and Intracranial Field Potentials

2003 • 97 citations

Simultaneous recording of EEG and BOLD responses: A historical perspective

2007 • 95 citations

Integrated local correlation: A new measure of local coherence in fMRI data

2007 • 95 citations

From single-trial EEG to brain area dynamics

2002 • 95 citations

Atrophy is associated with posterior cingulate white matter disruption in dementia with Lewy bodies and Alzheimer’s disease

2007 • 85 citations

Fronto-striatal deficit in Parkinson's disease during semantic event sequencing

2006 • 83 citations

Distinguishing low frequency oscillations within the 1/f spectral behaviour of electromagnetic brain signals

2007 • 82 citations

Failure to deactivate in autism: the co-constitution of self and other

2006 • 72 citations

A new integrative model of cerebral activation, deactivation and default mode function in Alzheimer’s disease

2008 • 59 citations

Very low frequency EEG oscillations and the resting brain in young adults: a preliminary study of localisation, stability and association with symptoms of inattention

2007 • 57 citations

Source estimation of spontaneous MEG oscillations in mild cognitive impairment

2006 • 51 citations

Differential interictal activity of the precuneus/posterior cingulate cortex revealed by resting state functional MRI at 3T in generalized vs. Partial seizure

2008 • 42 citations

Wavelets as alternative to short-time Fourier transform in signal-averaged electrocardiography

1995 • 34 citations

Abnormal default-mode network activation in cirrhotic patients: a functional magnetic resonance imaging study

2007 • 28 citations

Phase synchrony and coherence analyses of EEG as tools to discriminate between children with and without attention deficit disorder

2006 • 22 citations

Combined MEG and EEG methodology for non-invasive recording of infraslow activity in the human cortex

2007 • 20 citations