Prognostic Significance of MMP-1 and MMP-3 Functional Promoter Polymorphisms in Colorectal Cancer

Matrix Metalloproteinases and Tissue Inhibitors of Metalloproteinases

2003 • 4,348 citations

Matrix Metalloproteinases

1999 • 3,774 citations

A single nucleotide polymorphism in the matrix metalloproteinase-1 promoter creates an Ets binding site and augments transcription.

1998 • 532 citations

Role of matrix metalloproteinases (MMPs) in colorectal cancer

2003 • 495 citations

Progression of Coronary Atherosclerosis Is Associated with a Common Genetic Variant of the Human Stromelysin-1 Promoter Which Results in Reduced Gene Expression

1996 • 495 citations

Matrix metalloproteinase–1 is associated with poor prognosis in colorectal cancer

1996 • 449 citations

Polymorphism in matrix metalloproteinase gene promoters: implication in regulation of gene expression and susceptibility of various diseases

2000 • 378 citations

Roles of Matrix Metalloproteinases in Tumor Metastasis and Angiogenesis

2003 • 316 citations

Colorectal cancer

1999 • 312 citations

Matrix metalloproteinase–1 is associated with poor prognosis in colorectal cancer

1996 • 312 citations

Preliminary report: genetic variation in the human stromelysin promoter is associated with progression of coronary atherosclerosis.

1995 • 255 citations

A single nucleotide polymorphism in the matrix metalloproteinase-1 promoter enhances lung cancer susceptibility.

2001 • 222 citations

Correlation between expression of the matrix metalloproteinase-1 gene in ovarian cancers and an insertion/deletion polymorphism in its promoter region.

1999 • 218 citations

Distribution of collagenase and tissue inhibitor of metalloproteinases (TIMP) in colorectal tumours

1991 • 192 citations

New insights into the roles of matrix metalloproteinases in colorectal cancer development and progression

2003 • 168 citations

Matrix metalloproteinase-1 promoter polymorphism 1G/2G is correlated with colorectal cancer invasiveness.

2001 • 155 citations

Association of functional polymorphisms of matrix metalloproteinase (MMP)‐1 and MMP‐3 genes with colorectal cancer

2002 • 128 citations

Invasiveness of cutaneous malignant melanoma is influenced by matrix metalloproteinase 1 gene polymorphism.

2001 • 122 citations

A single nucleotide polymorphism in the matrix metalloproteinase-3 promoter enhances breast cancer susceptibility.

2002 • 119 citations

A relationship between Matrix metalloproteinase-1 (MMP-1) promoter polymorphism and cervical cancer progression

2003 • 49 citations

Single nucleotide polymorphisms in MMP1 and MMP3 gene promoters as risk factor in head and neck squamous cell carcinoma.

2004 • 40 citations

Matrix Metalloproteinase 3 Polymorphism

2004 • 40 citations

Clinical Factors and Biomarkers Which Affect a New Universal Grading System for Ovarian Epithelial Carcinoma

2001 • 7 citations