Carboxylic ionophores enhance the cytotoxic potency of ligand- and antibody-delivered ricin A chain.

Human chronic myelogenous leukemia cell-line with positive Philadelphia chromosome

1975 • 2,865 citations

Human chronic myelogenous leukemia cell-line with positive Philadelphia chromosome

1975 • 2,228 citations

Biological Applications of Ionophores

1976 • 1,829 citations

pH and the recycling of transferrin during receptor-mediated endocytosis.

1983 • 1,165 citations

One molecule of diphtheria toxin fragment a introduced into a cell can kill the cell

1978 • 744 citations

Receptor-mediated endocytosis of transferrin in K562 cells.

1983 • 576 citations

Entry of lethal doses of abrin, ricin and modeccin into the cytosol of HeLa cells

1980 • 305 citations

Ribosome Inactivation by the Toxic Lectins Abrin and Ricin

1975 • 208 citations

Kinetics of protein synthesis inactivation by ricin-anti-Thy 1.1 monoclonal antibody hybrids. Role of the ricin B subunit demonstrated by reconstitution.

1982 • 200 citations

Immunotoxins: Hybrid Molecules Combining High Specificity and Potent Cytotoxicity

1982 • 181 citations

Inhibition of Human Acute Lymphoblastic Leukemia Cells by Immunotoxins: Potentiation by Chloroquine

1984 • 124 citations

Monoclonal antibody-ricin A chain conjugate selectively cytotoxic for cells bearing the common acute lymphoblastic leukemia antigen.

1982 • 111 citations

A highly cytotoxic human transferrin-ricin A chain conjugate used to select receptor-modified cells.

1984 • 94 citations

Synergy of ricin A chain-containing immunotoxins and ricin B chain-containing immunotoxins in in vitro killing of neoplastic human B cells.

1983 • 89 citations

Enhancement of toxicity of antitransferrin receptor antibody-Pseudomonas exotoxin conjugates by adenovirus.

1983 • 72 citations

Specific cytotoxicity of a human immunoglobulin-directed Fab'-ricin A chain conjugate.

1980 • 65 citations

Monoclonal Antibodies as Cell Targeted Carriers of Covalently and Non-Covalently Attached Toxins

1984 • 9 citations

Study of the Transferrin Receptor Using a Cytotoxic Human Transferrin-Ricin a Chain Conjugate

1984 • 8 citations