β -Adrenoceptor-mediated Inhibition of IFN- γ , IL-3, and GM-CSF mRNA Accumulation in Activated Human T Lymphocytes Is Solely Mediated by the β₂-Adrenoceptor Subtype

A technique for radiolabeling DNA restriction endonuclease fragments to high specific activity

1983 • 26,063 citations

Costimulation of T lymphocytes: the role of CD28, CTLA-4, and B7/BB1 in interleukin-2 production and immunotherapy

1992 • 1,290 citations

Molecular Characterization of the Human β ₃ -Adrenergic Receptor

1989 • 1,071 citations

Modulation of Inflammation and Immunity by Cyclic AMP

1974 • 923 citations

Prostaglandin E2 inhibits production of Th1 lymphokines but not of Th2 lymphokines.

1991 • 835 citations

Atypical β-adrenoceptor on brown adipocytes as target for anti-obesity drugs

1984 • 724 citations

Prostaglandin E2 differentially modulates cytokine secretion profiles of human T helper lymphocytes.

1993 • 491 citations

ADENYLATE CYCLASE-COUPLED BETA-ADRENERGIC RECEPTORS: Structure and Mechanisms of Activation and Desensitization

1983 • 486 citations

Prostaglandin E inhibits the production of human interleukin 2.

1982 • 423 citations

Phenotype of cells expressing mRNA for TH2-type (interleukin 4 and interleukin 5) and TH1-type (interleukin 2 and interferon gamma) cytokines in bronchoalveolar lavage and bronchial biopsies from atopic asthmatic and normal control subjects.

1995 • 342 citations

Endogenous norepinephrine regulates tumor necrosis factor-alpha production from macrophages in vitro.

1994 • 268 citations

Cholera toxin discriminates between T helper 1 and 2 cells in T cell receptor-mediated activation: role of cAMP in T cell proliferation.

1990 • 238 citations

How should values of pA2 and affinity constants for pharmacological competitive antagonists be estimated?

1978 • 238 citations

cAMP inhibits induction of interleukin 2 but not of interleukin 4 in T cells.

1990 • 218 citations

Independent regulation of M-CSF and G-CSF gene expression in human monocytes

1988 • 200 citations

Beta adrenergic receptors in lymphocyte subpopulations

1980 • 150 citations

Mechanisms of beta-adrenergic receptor regulation in lungs and its implications for physiological responses

1992 • 109 citations

The beta-adrenergic system and allergic bronchial asthma: changes in lymphocyte beta-adrenergic receptor number and adenylate cyclase activity after an allergen-induced asthmatic attack

1982 • 102 citations

IL-7 differentially modulates the expression of IFN-gamma and IL-4 in activated human T lymphocytes by transcriptional and post-transcriptional mechanisms.

1996 • 72 citations

Interleukin-4 gene expression in activated human T lymphocytes is regulated by the cyclic adenosine monophosphate-dependent signaling pathway

1996 • 57 citations

Differences in functional cyclic AMP compartments mediating lepolysis by isoprenaline and BRL 37344 in four adipocyte types

1991 • 50 citations

Transcriptional and posttranscriptional regulation of the interleukin-4 and interleukin-3 genes in human T cells

1993 • 49 citations

Hormone receptors on cloned T lymphocytes. Increased responsiveness to histamine, prostaglandins, and beta-adrenergic agents as a late stage event in T cell activation.

1988 • 41 citations

Activation of the cAMP-dependent signaling pathway downregulates the expression of interleukin-3 and granulocyte-macrophage colony-stimulating factor in activated human T lymphocytes.

1996 • 23 citations

Extraction of cyclic amp for the determination in the competitive protein binding assay

1980 • 21 citations

Density and agonist‐promoted high and low affinity states of the β‐adrenoceptor on human B‐ and T‐cells

1988 • 20 citations

?-Adrenoceptor studies

1977 • 14 citations

Influence of adrenergic agonists and antagonists on lymphokine secretion in vitro

1987 • 12 citations

Defect in potentiation of adenylyl cyclase correlates with bronchial hyperreactivity

1995 • 10 citations