Distribution and concordance of N-acetyltransferase genotype and phenotype in an American population.

A Coefficient of Agreement for Nominal Scales

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Density Estimation for Statistics and Data Analysis

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Human ArylamineN-Acetyltransferase Genes: Isolation, Chromosomal Localization, and Functional Expression

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Determination of CYP1A2 and NAT2 phenotypes in human populations by analysis of caffeine urinary metabolites

1992 • 417 citations

Nomenclature for N-acetyltransferases

1995 • 378 citations

Arylamine N-acetyltransferase (NAT2) mutations and their allelic linkage in unrelated Caucasian individuals: correlation with phenotypic activity.

1995 • 335 citations

Cigarette Smoking, N-Acetyltransferase 2 Genetic Polymorphisms, and Breast Cancer Risk

1996 • 334 citations

Acetylator genotype and arylamine-induced carcinogenesis

1988 • 325 citations

SHORT COMMUNICATION: Genotype/phenotype discordance for human arylamine N-acetyltransferase (NAT2) reveals a new slow-acetylator allele common in African-Americans

1993 • 293 citations

Diagnosis of polymorphisms in carcinogen-activating and inactivating enzymes and cancer susceptibility-a review

1995 • 277 citations

Monomorphic and polymorphic human arylamine N-acetyltransferases: a comparison of liver isozymes and expressed products of two cloned genes.

1991 • 248 citations

Acetylation phenotype in colorectal carcinoma.

1987 • 244 citations

A prospective study of N-acetyltransferase genotype, red meat intake, and risk of colorectal cancer.

1998 • 234 citations

Polymorphisms for aromatic amine metabolism in humans: relevance for human carcinogenesis.

1992 • 229 citations

Slow acetylator mutations in the human polymorphic N-acetyltransferase gene in 786 Asians, blacks, Hispanics, and whites: application to metabolic epidemiology.

1993 • 209 citations

Cigarette smoking, N-acetyltransferases 1 and 2, and breast cancer risk.

1998 • 198 citations

Trimodality of isoniazid elimination: phenotype and genotype in patients with tuberculosis.

1997 • 191 citations

The Acetylator Genes and Drug Response

1987 • 183 citations

N-acetyltransferase polymorphism

1991 • 171 citations

The role of N-acetylation polymorphisms in smoking-associated bladder cancer: evidence of a gene-gene-exposure three-way interaction.

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Homozygous rapid arylamine N-acetyltransferase (NAT2) genotype as a susceptibility factor for lung cancer.

1996 • 139 citations

Relevance of metabolic polymorphisms to human carcinogenesis: evaluation of epidemiologic evidence

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Variations between individuals and populations in the acetylation of isoniazid and its significance for the treatment of pulmonary tuberculosis

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Arylamine N-acetyltransferase 1 (NAT1) and 2 (NAT2) polymorphisms in susceptibility to bladder cancer: the influence of smoking.

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Acetylation phenotype, carcinogen-hemoglobin adducts, and cigarette smoking.

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Molecular genetics of human polymorphic N-acetyltransferase: enzymatic analysis of 15 recombinant wild-type, mutant, and chimeric NAT2 allozymes

1994 • 118 citations

Molecular genetics of the N-acetyltransferases

1993 • 112 citations

N-acetyl transferase 2 genotypes, meat intake and breast cancer risk

1999 • 104 citations

Salmonella typhimurium strains expressing human arylamine N-acetyltransferases: metabolism and mutagenic activation of aromatic amines.

1992 • 103 citations

NAT2, GSTM-1, cigarette smoking, and risk of colon cancer.

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Prediction of phenotype for acetylation and for debrisoquine hydroxylation by DNA-tests in healthy human volunteers

1992 • 60 citations

Misclassification of genetic susceptibility biomarkers: implications for case-control studies and cross-population comparisons.

1993 • 59 citations

Predictors of N-acetyltransferase activity: should caffeine phenotyping and NAT2 genotyping be used interchangeably in epidemiological studies?

1996 • 45 citations

Human N-acetylation genotype determination with urinary caffeine metabolites

1990 • 44 citations

NAT2*12A (803A???G) codes for rapid arylamine N-acetylatioii in humans

1996 • 37 citations

Testing for bimodality in frequency distributions of data suggesting polymorphisms of drug metabolism‐histograms and probit plots.

1989 • 32 citations

Arylamine N-acetyltransferase (NAT2) genotypes in a Turkish population

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Polymorphic arylamine N-acetyltransferase (NAT2) genes in children with insulin-dependent diabetes mellitus

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[Cancer in Japanese migrants to Hawaii: interaction between genes and environment].

1992 • 28 citations

An improved method for genotyping ofN-acetyltransferase polymorphism by polymerase chain reaction

1993 • 27 citations

Acetylation phenotype and genotype in Aboriginal leprosy patients from the north-west region of Western Australia

1993 • 20 citations

Clinical implications of isoniazid, PAS and streptomycin blood levels in pulmonary tuberculosis.

1957 • 13 citations

Heterocyclic amines, cytochrome P4501A2, and N-acetyltransferase: Issues involved in incorporating putative genetic susceptibility markers into epidemiological studies

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Segregation analyses of four urinary caffeine metabolite ratios implicated in the determination of human acetylation phenotypes

1994 • 6 citations