Nitric Oxide Can Increase Heart Rate by Stimulating the Hyperpolarization-Activated Inward Current, I _f

Superoxide anion is involved in the breakdown of endothelium-derived vascular relaxing factor

1986 • 2,416 citations

Nitric oxide directly activates calcium-dependent potassium channels in vascular smooth muscle

1994 • 1,704 citations

Mechanism of vascular smooth muscle relaxation by organic nitrates, nitrites, nitroprusside and nitric oxide: evidence for the involvement of S-nitrosothiols as active intermediates.

1981 • 1,624 citations

S-nitrosylation of proteins with nitric oxide: synthesis and characterization of biologically active compounds.

1992 • 1,454 citations

Contribution of two types of calcium currents to the pacemaker potentials of rabbit sino‐atrial node cells.

1988 • 780 citations

Nitric Oxide and Cardiac Function

1996 • 721 citations

Cardiac pacemaking in the sinoatrial node

1993 • 665 citations

Expression of Inducible Nitric Oxide Synthase in Human Heart Failure

1996 • 496 citations

The Biochemical Pathways of Nitric Oxide Formation from Nitrovasodilators

1991 • 478 citations

Redox modulation of L-type calcium channels in ferret ventricular myocytes. Dual mechanism regulation by nitric oxide and S-nitrosothiols.

1996 • 444 citations

Acute effects of nitric oxide on left ventricular relaxation and diastolic distensibility in humans. Assessment by bicoronary sodium nitroprusside infusion.

1994 • 378 citations

Inhibitory actions of ZENECA ZD7288 on whole‐cell hyperpolarization activated inward current (I_f) in guinea‐pig dissociated sinoatrial node cells

1993 • 306 citations

LY 83583 interferes with the release of endothelium-derived relaxing factor and inhibits soluble guanylate cyclase.

1988 • 205 citations

Characterization of the Hyperpolarization-Activated Current, I _f , in Ventricular Myocytes From Human Failing Heart

1997 • 187 citations

Myocardial contractile dysfunction in the systematic inflammatory response syndrome: Role of a cytokine-inducible nitric oxide synthase in cardiac myocytes

1995 • 184 citations

Paracrine modulation of heart cell function by endothelial cells

1996 • 156 citations

Pacemaking in rabbit isolated sino‐atrial node cells during Cs+ block of the hyperpolarization‐activated current if.

1990 • 147 citations

Regulation of blood-brain barrier endothelial cells by nitric oxide.

1994 • 145 citations

A cellular mechanism for nitric oxide-mediated cholinergic control of mammalian heart rate.

1995 • 144 citations

Nitric Oxide Synthase (NOS3)–Mediated Cholinergic Modulation of Ca ²⁺ Current in Adult Rabbit Atrioventricular Nodal Cells

1996 • 134 citations

Iodine-123 metaiodobenzylguanidine scintigraphic assessment of the transplanted human heart: Evidence for late reinnervation

1995 • 133 citations

Hydroxyl radical-dependent inactivation of guanylate cyclase in cerebral arterioles by methylene blue and by LY83583.

1993 • 125 citations

Effects of NO Modulation on Cardiac Arrhythmias in the Rat Isolated Heart

1995 • 122 citations

Novel guanylyl cyclase inhibitor potently inhibits cyclic GMP accumulation in endothelial cells and relaxation of bovine pulmonary artery.

1996 • 98 citations

Hypoglycaemic and insulinotropic effects of a novel oral antidiabetic agent, (−)‐N‐(trans‐4‐isopropylcyclohexane‐carbonyl)‐<scp>d</scp>‐phenylalanine (A‐4166)

1997 • 91 citations

The onset and autonomic regulation of cardiac pacemaker activity: relevance of the f current

1995 • 89 citations

Effect of LY 83583 on relaxation induced by non-adrenergic non-cholinergic nerve stimulation and exogenous nitric oxide in the rat gastric fundus

1992 • 74 citations

Two components of the delayed rectifier potassium current, IK, in rabbit sino‐atrial node cells

1996 • 71 citations

Inhibition of nitrergic relaxations by a selective inhibitor of the soluble guanylate cyclase

1996 • 64 citations

Effects of orthotopic heart transplantation on sympathetic control mechanisms in congestive heart failure

1986 • 63 citations

Modulation of vagal actions on heart rate produced by inhibition of nitric oxide synthase in the anaesthetized ferret

1996 • 48 citations

Role of nitric oxide in the renin and heart rate responses to beta-adrenergic stimulation.

1994 • 21 citations

Effects of High Potassium and the Bradycardic Agents ZD7288 and Cesium on Heart Rate of Rabbits and Guinea Pigs

1995 • 20 citations

Clinical and hemodynamic effects of the new dilator drug molsidomine

1985 • 2 citations