Gene × Environment Interactions at the Serotonin Transporter Locus

Influence of Life Stress on Depression: Moderation by a Polymorphism in the 5-HTT Gene

2003 • 8,039 citations

Allelic Variation of Human Serotonin Transporter Gene Expression

1996 • 2,225 citations

Searching for genetic determinants in the new millennium

2000 • 1,878 citations

Problems of reporting genetic associations with complex outcomes

2003 • 1,221 citations

Social supports and serotonin transporter gene moderate depression in maltreated children

2004 • 806 citations

Brain-Derived Neurotrophic Factor–5-HTTLPR Gene Interactions and Environmental Modifiers of Depression in Children

2006 • 688 citations

Gene–environment interaction analysis of serotonin system markers with adolescent depression

2004 • 671 citations

The Interaction of Stressful Life Events and a Serotonin Transporter Polymorphism in the Prediction of Episodes of Major Depression

2005 • 652 citations

Meta-analysis of genetic association studies

2004 • 639 citations

The moderation by the serotonin transporter gene of environmental adversity in the aetiology of mental illness: review and methodological analysis

2007 • 506 citations

Epidemiological methods for studying genes and environmental factors in complex diseases

2001 • 473 citations

Early Family Environment, Current Adversity, the Serotonin Transporter Promoter Polymorphism, and Depressive Symptomatology

2006 • 432 citations

Association of a Triallelic Serotonin Transporter Gene Promoter Region (5-HTTLPR) Polymorphism With Stressful Life Events and Severity of Depression

2006 • 369 citations

Life events, first depression onset and the serotonin transporter gene

2006 • 316 citations

The relationship between stressful life events, the serotonin transporter (5-HTTLPR) genotype and major depression

2004 • 306 citations

Mental and physical distress is modulated by a polymorphism in the 5-HT transporter gene interacting with social stressors and chronic disease burden

2004 • 293 citations

Interactions Between Life Stressors and Susceptibility Genes (5-HTTLPR and BDNF) on Depression in Korean Elders

2007 • 284 citations

Social Adversity, the Serotonin Transporter (5-HTTLPR) Polymorphism and Major Depressive Disorder

2005 • 271 citations

Evidence for a Gene-Environment Interaction in Predicting Behavioral Inhibition in Middle Childhood

2005 • 264 citations

Meta-analysis of serotonin transporter polymorphisms and affective disorders

2004 • 261 citations

Development of depression: sex and the interaction between environment and a promoter polymorphism of the serotonin transporter gene

2005 • 251 citations

Gene-by-Environment (Serotonin Transporter and Childhood Maltreatment) Interaction for Anxiety Sensitivity, an Intermediate Phenotype for Anxiety Disorders

2007 • 247 citations

The Serotonin Transporter Length Polymorphism, Neuroticism, and Depression: A Comprehensive Assessment of Association

2005 • 212 citations

Stress-Related Negative Affectivity and Genetically Altered Serotonin Transporter Function

2006 • 191 citations

Effect modification and the limits of biological inference from epidemiologic data

1991 • 172 citations

Genotype × Environment Interaction in Psychopathology: Fact or Artifact?

2006 • 165 citations

The risk for depression conferred by stressful life events is modified by variation at the serotonin transporter 5HTTLPR genotype: evidence from the Spanish PREDICT-Gene cohort

2007 • 139 citations

Serotonin Transporter Gene Polymorphism (5-HTTLPR) and Anxiety Reactivity in Daily Life: A Daily Process Approach to Gene-Environment Interaction

2007 • 135 citations

Genotype × Environment Interaction in Psychopathology: Fact or Artifact?

2006 • 110 citations

Serotonin Transporter (5‐HTTLPR) Genotype, Childhood Abuse, and Suicide Attempts in Adult Psychiatric Inpatients

2006 • 73 citations

Effects of stressful life events, maternal depression and 5‐HTTLPR genotype on emotional symptoms in pre‐adolescent children

2008 • 64 citations

Depressive symptoms in mid‐pregnancy, lifetime stressors and the 5‐HTTLPR genotype

2006 • 61 citations