Bile acid-induced liver toxicity: Relation to the hydrophobic-hydrophilic balance of bile acids

The hydrophobic-hydrophilic balance of bile salts. Inverse correlation between reverse-phase high performance liquid chromatographic mobilities and micellar cholesterol-solubilizing capacities.

1982 • 375 citations

The Binding of Deoxycholate and Triton X-100 to Proteins

1973 • 371 citations

Influence of Hydroxylation and Conjugation of Bile Salts on Their Membrane-Damaging Properties-Studies on Isolated Hepatocytes and Lipid Membrane Vesicles

1984 • 290 citations

Bile Acids, Liver Injury, and Liver Disease

1972 • 268 citations

Bile acid sulfates. I. Synthesis of lithocholic acid sulfates and their identification in human bile

1971 • 224 citations

Mechanisms of Hepatic Bile Formation

1977 • 160 citations

Sulfation and Renal Excretion of Bile Salts in Patients with Cirrhosis of the Liver

1975 • 149 citations

Metabolism of steroid and amino acid moieties of conjugated bile acids in man

1972 • 146 citations

Effect of Deoxycholic Acid Ingestion on Bile Acid Metabolism and Biliary Lipid Secretion in Normal Subjects

1977 • 138 citations

Effects of bile salts on the plasma membranes of isolated rat hepatocytes

1980 • 138 citations

Pathogenesis of lithocholate- and taurolithocholate-induced intrahepatic cholestasis in rats.

1978 • 136 citations

Bile Acid Metabolism in Health and Disease

1978 • 123 citations

The Lipid composition of plasma membrane subfractions originating from the three major functional domains of the rat hepatocyte cell surface

1976 • 114 citations

Effect of dietary chenodeoxycholic acid and lithocholic acid in the rabbit

1974 • 99 citations

Efficacy and indications of ursodeoxycholic acid treatment for dissolving gallstones

1980 • 97 citations

Effects of different bile salts upon the composition and morphology of a liver plasma membrane preparation. Deoxycholate is more membrane damaging than cholate and its conjugates

1977 • 94 citations

Lithocholate metabolism during chemotherapy for gallstone dissolution. 2. Absorption and sulphation.

1976 • 90 citations

Hepatic Lesions in Chronic Inflammatory Bowel Disease

1967 • 88 citations

Bile acid metabolism in mammals. I. Bile acid-induced intrahepatic cholestasis.

1971 • 69 citations

Enzyme profiles of mammalian bile

1975 • 67 citations

Comparative effects of ursodeoxycholic acid and chenodeoxycholic acid in the rhesus monkey

1978 • 63 citations

Lithocholate metabolism during chenotherapy for gallstone dissolution. 1. Serum levels of sulphated and unsulphated lithocholates.

1976 • 62 citations

Toxicity of chenodeoxycholic acid in the nonhuman primate.

1975 • 60 citations

A Prospective Morphologic Evaluation of Hepatic Toxicity of Chenodeoxycholic Acid in Patients with Cholelithiasis: The National Cooperative Gallstone Study

1982 • 53 citations

Liver Disease in Ulcerative Colitis

1970 • 53 citations

Comparison of the effects between ursodeoxycholic and chenodeoxycholic acids on liver function and structure and on bile acid composition in the rhesus monkey

1980 • 50 citations

Bile Acids and Lipids

1982 • 47 citations

A Combination of Chenodeoxycholic Acid and Ursodeoxycholic Acid is more Effective than Either Alone in Reducing Biliary Cholesterol Saturation

1982 • 46 citations

Influence of primary bile acid feeding on cholesterol metabolism and hepatic function in the rhesus monkey.

1975 • 46 citations

Hepatotoxicity of bile acids in rabbits: ursodeoxycholic acid is less toxic than chenodeoxycholic acid.

1982 • 46 citations

Effects of sulfation patterns on intestinal transport of bile salt sulfate esters

1980 • 46 citations

Sulfation of Lithocholate as a Possible Modifier of Chenodeoxycholic Acid-induced Elevations of Serum Transaminase in Patients with Gallstones

1981 • 44 citations

Liver Cell Plasma Membrane Lipids and the Origin of Biliary Phospholipid

1975 • 41 citations

Ultrastructural evidence of intrahepatic cholestasis before and after chenodeoxycholic acid therapy in patients with cholelithiasis: the national cooperative gallstone study.

1983 • 34 citations

Portal vein bile acids in patients with severe inflammatory bowel disease

1980 • 33 citations

Ultrastructural Evidence of Intrahepatic Cholestasis Before and After Chenodeoxycholic Acid Therapy in Patients with Cholelithiasis: The National Cooperative Gallstone Study

1983 • 32 citations

Early Morphologic and Enzymatic Changes in Livers of Rats Treated with Chenodeoxycholic and Ursodeoxycholic Acids

1983 • 32 citations

Toxic Effects of Lithocholate on the Liver and Biliary Tree

1976 • 31 citations

Bile acid conjugation in the chimpanzee: effective sulfation of lithocholic acid

1978 • 28 citations

The effect of taurine administration on patients with acute hepatitis.

1983 • 28 citations

Comparative effects of ursodeoxycholic acid and chenodeoxycholic acid in the rhesus monkey

1978 • 27 citations

Enzymatic sulfation of bile salts: III. Enzymatic sulfation of taurolithocholate in human and guinea pig fetuses and adults

1978 • 25 citations

Hepatotoxic Effect of Bile Acids in Inflammatory Bowel Disease

1980 • 23 citations

The mechanism of bile salt-induced hemolysis.

2001 • 21 citations

Lithocholic acid, cholestasis, and liver disease.

1972 • 18 citations

Clinical studies on cheno- and ursodeoxycholic acid treatment for gallstone dissolution.

1980 • 15 citations

Untitled

1981 • 13 citations

Membrane Composition Affects Characteristics of Glycocholate-Induced Lysis of Erythrocytes

1979 • 9 citations

The hepatobiliary system — fundamental and pathological mechanism

1977 • 7 citations

How does bile acid pool composition regulate bile cholesterol saturation

1982 • 6 citations

Deleted Work

1955 • 0 citations

Cited By (0)

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