Survival and glial fate acquisition of neural crest cells are regulated by an interplay between the transcription factor Sox10 and extrinsic combinatorial signaling

Mammalian Neural Stem Cells

2000 • 4,689 citations

Regulatory Mechanisms in Stem Cell Biology

1997 • 1,060 citations

The transcription factor Sox10 is a key regulator of peripheral glial development

2001 • 868 citations

Sonic Hedgehog–Regulated Oligodendrocyte Lineage Genes Encoding bHLH Proteins in the Mammalian Central Nervous System

2000 • 839 citations

SOX10 mutations in patients with Waardenburg-Hirschsprung disease

1998 • 806 citations

Isolation of a stem cell for neurons and glia from the mammalian neural crest

1992 • 796 citations

Identification of a Novel Family of Oligodendrocyte Lineage-Specific Basic Helix–Loop–Helix Transcription Factors

2000 • 786 citations

Alternative Neural Crest Cell Fates Are Instructively Promoted by TGFβ Superfamily Members

1996 • 785 citations

Sox10, a Novel Transcriptional Modulator in Glial Cells

1998 • 759 citations

Glial growth factors are alternatively spliced erbB2 ligands expressed in the nervous system

1993 • 744 citations

Prospective Identification, Isolation by Flow Cytometry, and In Vivo Self-Renewal of Multipotent Mammalian Neural Crest Stem Cells

1999 • 738 citations

SOX10 mutation disrupts neural crest development in Dom Hirschsprung mouse model

1998 • 725 citations

Severe neuropathies in mice with targeted mutations in the ErbB3 receptor

1997 • 721 citations

Transient Notch Activation Initiates an Irreversible Switch from Neurogenesis to Gliogenesis by Neural Crest Stem Cells

2000 • 715 citations

Basic helix-loop-helix genes in neural development

1997 • 521 citations

rax, Hes1, and notch1 Promote the Formation of Müller Glia by Postnatal Retinal Progenitor Cells

2000 • 519 citations

Glial growth factor restricts mammalian neural crest stem cells to a glial fate

1994 • 496 citations

Progression from Extrinsic to Intrinsic Signaling in Cell Fate Specification

1999 • 495 citations

glial cells missing: a genetic switch that controls glial versus neuronal fate

1995 • 447 citations

Interaction among SOX10, PAX3 and MITF, three genes altered in Waardenburg syndrome

2000 • 445 citations

Glial cells missing: A binary switch between neuronal and glial determination in drosophila

1995 • 410 citations

The glial cells missing-1 protein is essential for branching morphogenesis in the chorioallantoic placenta

2000 • 408 citations

Helix-loop-helix factors in growth and differentiation of the vertebrate nervous system

1997 • 364 citations

Mutation of the Sry-related Sox10 gene in Dominant megacolon , a mouse model for human Hirschsprung disease

1998 • 354 citations

Transcription factor hierarchy in Waardenburg syndrome: regulation of MITF expression by SOX10 and PAX3

2000 • 336 citations

The ErbB2 and ErbB3 receptors and their ligand, neuregulin-1, are essential for development of the sympathetic nervous system

1998 • 334 citations

Mammalian achaete-scute and atonal homologs regulate neuronal versus glial fate determination in the central nervous system

2000 • 300 citations

Bone Morphogenetic Proteins Are Required In Vivo for the Generation of Sympathetic Neurons

1999 • 297 citations

Glial cell fate specification modulated by the bHLH gene Hes5in mouse retina

2000 • 269 citations

Combinatorial Signaling in the Specification of Unique Cell Fates

2000 • 260 citations

The cellular function of MASH1 in autonomic neurogenesis

1995 • 241 citations

Programmed Cell Death in Neurons: Focus on the Pathway of Nerve Growth Factor Deprivation-Induced Death of Sympathetic Neurons

1997 • 220 citations

Protein Zero Gene Expression Is Regulated by the Glial Transcription Factor Sox10

2000 • 216 citations

glide directs glial fate commitment and cell fate switch between neurones and glia

1996 • 213 citations

Isolation and characterization of mammalian homologs of the Drosophila gene glial cells missing

1998 • 201 citations

Community effects and related phenomena in development

1993 • 199 citations

Early Death of Neural Crest Cells is Responsible for Total Enteric Aganglionosis in Sox10^Dom/Sox10^Dom Mouse Embryos

1999 • 193 citations

Placental Failure in Mice Lacking the Mammalian Homolog of Glial Cells Missing, GCMa

2000 • 192 citations

Distinct isoforms of neuregulin are expressed in mesenchymal and neuronal cells during mouse development.

1994 • 180 citations

P0 and PMP22 mark a multipotent neural crest-derived cell type that displays community effects in response to TGF-β family factors

1999 • 177 citations

Role of neuregulins in glial cell development

2000 • 175 citations

Myelin deficiencies in both the central and the peripheral nervous systems associated with aSOX10 mutation

1999 • 174 citations

Sensory and Motor Neuron-derived Factor. A NOVEL HEREGULIN VARIANT HIGHLY EXPRESSED IN SENSORY AND MOTOR NEURONS

1995 • 170 citations

Postmigratory neural crest cells expressing c-RET display restricted developmental and proliferative capacities

1995 • 169 citations

Neurological Phenotype in Waardenburg Syndrome Type 4 Correlates with Novel SOX10 Truncating Mutations and Expression in Developing Brain

2000 • 161 citations

The Sox10^Dom Mouse: Modeling the Genetic Variation of Waardenburg-Shah (WS4) Syndrome

1999 • 148 citations

Independent regulation of the two Pax5 alleles during B-cell development

1999 • 142 citations

Deconstructing cell determination: proneural genes and neuronal identity

1999 • 137 citations

Lineages and transcription factors in the specification of vertebrate primary sensory neurons

1999 • 133 citations

Cell lineage determination and the control of neuronal identity in the neural crest.

1997 • 117 citations

Expression of the SOX10 gene during human development

1998 • 110 citations

Active killing of neurons during development and following stress: a role for p75NTR and Fas?

2000 • 108 citations

The Drosophila SOX-domain protein Dichaete is required for the development of the central nervous system midline

1998 • 106 citations

A Molecular Analysis of the Yemenite Deaf-Blind Hypopigmentation Syndrome: SOX10 Dysfunction Causes Different Neurocristopathies

1999 • 103 citations

The Basic Helix-Loop-Helix Genehesr2Promotes Gliogenesis in Mouse Retina

2001 • 101 citations

Peripheral neuropathy with hypomyelination, chronic intestinal pseudo-obstruction and deafness: A developmental ?neural crest syndrome? related to a SOX10 mutation

2000 • 94 citations

Transcriptional control in myelinating glia: Flavors and spices

2000 • 63 citations

The Ets Domain Transcription Factor Erm Distinguishes Rat Satellite Glia from Schwann Cells and Is Regulated in Satellite Cells by Neuregulin Signaling

2000 • 62 citations

Autonomic Neurogenesis and Apoptosis Are Alternative Fates of Progenitor Cell Communities Induced by TGFβ

2000 • 61 citations

Glia development in the embryonic CNS of Drosophila

1999 • 54 citations

Context-dependent regulation of fate decisions in multipotent progenitor cells of the peripheral nervous system

2001 • 41 citations

Embryonic gene expression resolved at the cellular level by fluorescence in situ hybridization

1999 • 25 citations