European Study Group on Diastolic Heart Failure

Pathological hypertrophy and cardiac interstitium. Fibrosis and renin-angiotensin-aldosterone system.

1991 • 2,017 citations

Role of diabetes in congestive heart failure: The Framingham study

1974 • 2,006 citations

Relation of transmitral flow velocity patterns to left ventricular diastolic function: New insights from a combined hemodynamic and Doppler echocardiographic study

1988 • 1,571 citations

Human heart: tagging with MR imaging--a method for noninvasive assessment of myocardial motion.

1988 • 1,429 citations

Evaluation of Diastolic Filling of Left Ventricle in Health and Disease: Doppler Echocardiography Is the Clinician’s Rosetta Stone

1997 • 1,271 citations

Hemodynamic determinants of the time-course of fall in canine left ventricular pressure.

1976 • 1,078 citations

Oxygen utilization and ventilation during exercise in patients with chronic cardiac failure.

1982 • 918 citations

Prevalence, clinical features and prognosis of diastolic heart failure: An epidemiologic perspective

1995 • 901 citations

Estimation of left ventricular filling pressures using two-dimensional and Doppler echocardiography in adult patients with cardiac disease

1993 • 776 citations

Evidence for Cardiomyopathy in Familial Diabetes Mellitus

1977 • 718 citations

Congestive heart failure with normal systolic function

1984 • 623 citations

Pulmonary venous flow velocities recorded by transthoracic Doppler ultrasound: Relation to left ventricular diastolic pressures

1993 • 616 citations

Increased rat cardiac angiotensin converting enzyme activity and mRNA expression in pressure overload left ventricular hypertrophy. Effects on coronary resistance, contractility, and relaxation.

1990 • 607 citations

Impaired left ventricular diastolic filling in patients with coronary artery disease: assessment with radionuclide angiography.

1981 • 585 citations

Extracellular Matrix Remodeling in Heart Failure

1997 • 560 citations

Intact systolic left ventricular function in clinical congestive heart failure

1985 • 534 citations

Abnormal left ventricular filling: An early finding in mild to moderate systemic hypertension

1984 • 530 citations

The effect of diabetes mellitus on prognosis and serial left ventricular function after acute myocardial infarction: Contribution of both coronary disease and diastolic left ventricular dysfunction to the adverse prognosis

1989 • 514 citations

Relation of pulmonary vein to mitral flow velocities by transesophageal Doppler echocardiography. Effect of different loading conditions.

1990 • 505 citations

Doppler index combining systolic and diastolic myocardial performance: Clinical value in cardiac amyloidisis

1996 • 501 citations

Left ventricular myocardial structure in aortic valve disease before, intermediate, and late after aortic valve replacement.

1989 • 483 citations

Left ventricular flow propagation during early filling is related to wall relaxation: A color M-mode Doppler analysis

1992 • 482 citations

An Index of Early Left Ventricular Filling That Combined With Pulsed Doppler Peak E Velocity May Estimate Capillary Wedge Pressure

1997 • 471 citations

Volume loading slows left ventricular isovolumic relaxation rate. Evidence of load-dependent relaxation in the intact dog heart.

1981 • 451 citations

Systolic and diastolic dysfunction in patients with clinical diagnosis of dilated cardiomyopathy. Relation to symptoms and prognosis.

1994 • 447 citations

Prognostic value of Doppler transmitral flow patterns in patients with congestive heart failure

1994 • 435 citations

Restrictive left ventricular filling pattern in dilated cardiomyopathy assessed by doppler echocardiography: Clinical, echocardiographic and hemodynamic correlations and prognostic implications

1993 • 435 citations

Echocardiographic Doppler evaluation of left ventricular diastolic function. Physics and physiology.

1991 • 422 citations

Combined influence of ventricular loading and relaxation on the transmitral flow velocity profile in dogs measured by Doppler echocardiography.

1988 • 416 citations

Noninvasive assessment of left ventricular diastolic function by pulsed doppler echocardiography in patients with hypertrophic cardiomyopathy

1987 • 415 citations

Left ventricular relaxation and filling pattern in different forms of left ventricular hypertrophy: An echocardiographic study

1980 • 407 citations

Three-dimensional left ventricular deformation in hypertrophic cardiomyopathy.

1994 • 404 citations

Left Ventricular Diastolic Dysfunction as a Cause of Congestive Heart Failure

1992 • 394 citations

Left ventricular diastolic function in hypertension: relation to left ventricular mass and systolic function

1984 • 361 citations

Doppler-derived mitral deceleration time of early filling as a strong predictor of pulmonary capillary wedge pressure in postinfarction patients with left ventricular systolic dysfunction

1994 • 359 citations

Prognostic significance of Doppler measures of diastolic function in cardiac amyloidosis. A Doppler echocardiography study.

1991 • 350 citations

Diastolic Dysfunction in Congestive Heart Failure

1991 • 349 citations

Dissociation between left ventricular untwisting and filling. Accentuation by catecholamines.

1992 • 346 citations

Relaxation and diastole of the heart

1989 • 338 citations

A comparison of the pathological spectrum of hypertensive, diabetic, and hypertensive-diabetic heart disease.

1990 • 338 citations

Doppler characterization of left ventricular diastolic function in cardiac amyloidosis

1989 • 337 citations

Diastolic failure: Pathophysiology and therapeutic implications

1993 • 321 citations

A practical guide to assessment of ventricular diastolic function using doppler echocardiography

1996 • 318 citations

Relation of regional cross-fiber shortening to wall thickening in the intact heart. Three-dimensional strain analysis by NMR tagging.

1994 • 317 citations

Determination of Left Ventricular Chamber Stiffness From the Time for Deceleration of Early Left Ventricular Filling

1995 • 310 citations

Effects of Age on Left Ventricular Dimensions and Filling Dynamics in 117 Normal Persons

1994 • 302 citations

A clinical study of left ventricular relaxation.

1980 • 294 citations

Evaluation of left ventricular systolic and diastolic dysfunction during transient myocardial ischemia produced by angioplasty

1987 • 293 citations

Changes in Diastolic Stiffness and Tone of the Left Ventricle During Angina Pectoris

1974 • 279 citations

Doppler Assessment of Pulmonary Venous Flow in Healthy Subjects and in Patients with Heart Disease

1991 • 263 citations

Analysis of left ventricular wall movement during isovolumic relaxation and its relation to coronary artery disease.

1976 • 250 citations

The Natural History of Left Ventricular Filling Abnormalities: Assessment by Two‐Dimensional and Doppler Echocardiography

1992 • 249 citations

Persistence of Restrictive Left Ventricular Filling Pattern in Dilated Cardiomyopathy: An Ominous Prognostic Sign

1997 • 247 citations

Modification of abnormal left ventricular diastolic properties by nifedipine in patients with hypertrophic cardiomyopathy.

1982 • 244 citations

Normalization of Diastolic Dysfunction in Aortic Stenosis Late After Valve Replacement

1995 • 236 citations

Effects of abnormal activation on the time course of the left ventricular pressure pulse in dilated cardiomyopathy

1992 • 236 citations

Left ventricular relaxation in the filling and nonfilling intact canine heart

1986 • 230 citations

The Rate of Change of Left Ventricular Volume in Man

1974 • 229 citations

Diagnosis and Treatment of Heart Failure Based on Left Ventricular Systolic or Diastolic Dysfunction

1994 • 223 citations

Clinical evaluation of left ventricular diastolic performance

1990 • 217 citations

Influence of collagen network on left ventricular systolic and diastolic function in aortic valve disease

1993 • 216 citations

Heart failure with normal ejection fraction. The V-HeFT study

1990 • 214 citations

Exercise capacity for survivors of cardiac transplantation or sustained medical therapy for stable heart failure.

1990 • 213 citations

Intraventricular early diastolic filling during acute myocardial ischemia, assessment by multigated color m-mode Doppler echocardiography.

1993 • 210 citations

Abnormalities of diastolic function as a potential cause of exercise intolerance in chronic heart failure.

1990 • 206 citations

Echocardiographic assessment of left ventricular filling and septal and posterior wall dynamics in idiopathic hypertrophic subaortic stenosis.

1978 • 206 citations

Evaluation of left ventricular segmental wall motion in hypertrophic cardiomyopathy with myocardial tagging.

1992 • 203 citations

Myocardial relaxation. II. Hemodynamic determinants of rate of left ventricular isovolumic pressure decline

1980 • 200 citations

Viscoelastic properties of the diastolic left ventricle in the conscious dog.

1977 • 195 citations

Left ventricular filling dynamics and diastolic function

1990 • 194 citations

Prolonged Kinetics of Recovery of Oxygen Consumption After Maximal Graded Exercise in Patients With Chronic Heart Failure

1995 • 193 citations

Noninvasive assessment of left and right ventricular filling in myocardial infarction with a two-dimensional Doppler echocardiography method

1985 • 188 citations

Left ventricular relaxation and filling in hypertrophic cardiomyopathy. An echocardiographic study.

1978 • 184 citations

Loading Manipulations Improve the Prognostic Value of Doppler Evaluation of Mitral Flow in Patients With Chronic Heart Failure

1997 • 182 citations

Exercise-induced ischemia: the influence of altered relaxation on early diastolic pressures.

1983 • 182 citations

The functional defect in amyloid heart disease

1975 • 177 citations

Validation of tagging with MR imaging to estimate material deformation.

1993 • 177 citations

Congestive heart failure: Echocardiographic insights

1983 • 175 citations

Increased regional myocardial stiffness of the left ventricle during pacing-induced angina in man.

1983 • 175 citations

Sex-dependent differences in left ventricular function and structure in chronic pressure overload

1995 • 172 citations

Restrictive Left Ventricular Diastolic Filling Identifies Patients With Heart Failure After Acute Myocardial Infarction

1992 • 170 citations

Clinical profile of restrictive cardiomyopathy.

1980 • 169 citations

Dynamics of left ventricular filling at rest and during exercise.

1983 • 166 citations

Doppler echocardiography analysis of left ventricular filling in treated hypertensive patients

1987 • 165 citations

Improved left ventricular diastolic filling in patients with coronary artery disease after percutaneous transluminal coronary angioplasty.

1982 • 165 citations

Assessment of diastolic function in normal and hypertrophied hearts: Comparison of Doppler echocardiography and M-mode echocardiography

1987 • 163 citations

Hemodynamic determinants of maximum negative dP-dt and periods of diastole

1974 • 160 citations

Paracrine modulation of heart cell function by endothelial cells

1996 • 156 citations

Left ventricular hypertrophy. Relation of structure to diastolic function in hypertension.

1984 • 154 citations

Effects of aging on asynchronous left ventricular regional function and global ventricular filling in normal human subjects

1988 • 147 citations

Diastolic filling dynamics in patients with aortic stenosis.

1986 • 140 citations

A hemodynamic and Doppler echocardiographic study of ventricular function in long-term cardiac allograft recipients. Etiology and prognosis of restrictive-constrictive physiology.

1989 • 139 citations

Marked Discordance Between Dynamic and Passive Diastolic Pressure-Volume Relations in Idiopathic Hypertrophic Cardiomyopathy

1996 • 134 citations

Logistic Time Constant of Isovolumic Relaxation Pressure–Time Curve in the Canine Left Ventricle

1995 • 129 citations

Regional left ventricular asynchrony and impaired global left ventricular filling in hypertrophic cardiomyopathy: Effect of verapamil

1987 • 128 citations

Assessment of left ventricular relaxation by Doppler echocardiography. Comparison of isovolumic relaxation time and transmitral flow velocities with time constant of isovolumic relaxation.

1990 • 124 citations

Left ventricular relaxation in patients with left ventricular hypertrophy secondary to aortic valve disease.

1982 • 124 citations

Intracardiac angiotensin-converting enzyme inhibition improves diastolic function in patients with left ventricular hypertrophy due to aortic stenosis.

1994 • 123 citations

Effects of verapamil on left ventricular systolic and diastolic function in patients with hypertrophic cardiomyopathy: pressure-volume analysis with a nonimaging scintillation probe.

1983 • 119 citations

The natural history of isolated left ventricular diastolic dysfunction

1992 • 118 citations

Pulsed Doppler assessment of left ventricular diastolic filling in coronary artery disease before and immediately after coronary angioplasty

1987 • 117 citations

Diastolic function of the heart in untreated primary hypertension.

1984 • 111 citations

Diastolic Relaxation of the Heart

1994 • 111 citations

Myocardial relaxation and passive diastolic properties in man.

1986 • 110 citations

Influence of coronary occlusion during PTCA on end-systolic and end-diastolic pressure-volume relations in humans.

1990 • 110 citations

Changes in diastolic properties of the regional myocardium during pacing-induced ischemia in human subjects

1985 • 109 citations

Deficient acceleration of left ventricular relaxation during exercise after heart transplantation.

1992 • 109 citations

Effects of Brain Natriuretic Peptide on Exercise Hemodynamics and Neurohormones in Isolated Diastolic Heart Failure

1996 • 107 citations

Comparison of the effects of nitroprusside and nifedipine on diastolic properties in patients with hypertrophic cardiomyopathy: Altered left ventricular loading or improved muscle inactivation?

1983 • 107 citations

Influence of systolic pressure profile on rate of left ventricular pressure fall

1991 • 105 citations

Pulmonary venous flow velocity pattern as assessed with transthoracic pulsed Doppler echocardiography in subjects without cardiac disease

1991 • 104 citations

Nonuniform course of left ventricular pressure fall and its regulation by load and contractile state.

1994 • 103 citations

Noninvasive measurement of rate of left ventricular relaxation by Doppler echocardiography. Validation with simultaneous cardiac catheterization.

1993 • 99 citations

Left Ventricular Diastolic Dysfunction and Heart Failure

1994 • 99 citations

Evaluation of left ventricular diastolic function.

1989 • 97 citations

Improved left ventricular filling accompanies reduced left ventricular mass during therapy of essential hypertension

1986 • 96 citations

Relaxation–Systolic Pressure Relation

1997 • 95 citations

Noninvasive Assessment of the Ventricular Relaxation Time Constant (τ) in Humans by Doppler Echocardiography

1997 • 90 citations

Effects of induced asynchrony on left ventricular diastolic function in patients with coronary artery disease

1993 • 85 citations

Doppler echocardiographic evaluation of the effect of atrial pacing-induced ischemia on left ventricular filling in patients with coronary artery disease

1988 • 84 citations

Left Ventricular Diastolic Function in Hypertension and Role of Plasma Glucose and Insulin

1996 • 80 citations

Intracoronary angiotensin-converting enzyme inhibition improves diastolic function in patients with hypertensive left ventricular hypertrophy.

1994 • 80 citations

Age Dependency of Left Ventricular Diastolic Function in Pressure Overload Hypertrophy

1997 • 77 citations

Diastolic dysfunction in heart failure

1997 • 75 citations

Exacerbation of left ventricular ischemic diastolic dysfunction by pressure-overload hypertrophy. Modification by specific inhibition of cardiac angiotensin converting enzyme.

1992 • 74 citations

Radionuclide angiographic evaluation of left ventricular diastolic function.

1991 • 74 citations

Alterations in diastolic function in response to progressive left ventricular hypertrophy

1989 • 74 citations

Isovolumic relaxation period in hypertrophic cardiomyopathy

1984 • 74 citations

Effects of Aging on Left Ventricular Relaxation in Humans

1997 • 70 citations

Significance of Diastolic Dysfunction of the Heart

1991 • 67 citations

Diastolic heart failure

1994 • 66 citations

Shortened Doppler-derived mitral A wave deceleration time: An important predictor of elevated left ventricular filling pressure

1996 • 65 citations

Left ventricular systolic and diastolic function during acute coronary artery balloon occlusion in humans

1988 • 64 citations

Time constant of isovolumic pressure fall: new numerical approaches and significance

1984 • 64 citations

Effects of dual-chamber pacing in hypertrophic cardiomyopathy on left ventricular outflow tract obstruction and on diastolic function

1996 • 62 citations

The apexcardiogram in normal older subjects and in patients with arteriosclerotic heart disease. Effect of exercise on the “a” wave

1963 • 62 citations

Abnormal exercise hemodynamics in cardiac allograft recipients 1 year after cardiac transplantation. Relation to preload reserve.

1989 • 61 citations

Continuous wave Doppler echocardiography for noninvasive assessment of left ventricular dP/dt and relaxation time constant from mitral regurgitant spectra in patients

1994 • 61 citations

The Use of Apexcardiography in the Assessment of Left Ventricular Diastolic Pressure

1970 • 60 citations

Enhancement of Left Ventricular Relaxation in the Isolated Heart by an Angiotensin-Converting Enzyme Inhibitor

1995 • 60 citations

The diastolic mechanical properties of the intact left ventricle.

1980 • 59 citations

Abnormal subendocardial function in restrictive left ventricular disease.

1994 • 58 citations

Effects of coronary venous pressure on left ventricular diastolic distensibility.

1990 • 55 citations

Myocardial Cell Dysfunction in Diabetes Mellitus: A Review of Clinical and Experimental Studies

1986 • 49 citations

Diastolic dysfunction during acute cardiac allograft rejection.

1990 • 47 citations

ACE inhibitors unmask incoordinate diastolic wall motion in restrictive left ventricular disease.

1996 • 47 citations

Noninvasive Assessment of Left Ventricular Relaxation Using Continuous-Wave Doppler Aortic Regurgitant Velocity Curve

1995 • 45 citations

Doppler echocardiographic evaluation of left ventricular diastolic filling in isolated valvular aortic stenosis

1989 • 43 citations

Influence of exercise-induced myocardial ischemia on the pattern of left ventricular diastolic filling: A Doppler echocardiographic study

1991 • 42 citations

Evaluation of Time Course of Left Ventricular Isovolumic Relaxation in Humans

1987 • 40 citations

Incipient Cardiomyopathy in Young Insulin-dependent Diabetic Patients: A Seven-year Prospective Doppler Echocardiographic Study

1996 • 40 citations

Diastolic function of the nonfilling human left ventricle

1992 • 40 citations

Changes in left ventricular free wall thickness in patients with ischaemic heart disease.

1977 • 36 citations

Recovery of systolic and diastolic left ventricular function after a 60-second coronary arterial occlusion during percutaneous transluminal coronary angioplasty for angina pectoris

1987 • 31 citations

Mechanisms of reduced left ventricular filling rate in coronary artery disease.

1983 • 27 citations

Load dependence of left ventricular diastolic pressure-volume relations during short-term coronary artery occlusion.

1991 • 27 citations

Effects of pacing-induced ischemia on early left ventricular filling and regional myocardial dynamics and their modification by nifedipine.

1987 • 26 citations

Relation of left ventricular isovolumic relaxation time and incoordination to transmitral Doppler filling patterns

1992 • 26 citations

Wide-range load shift of combined aortic valvuloplasty-arterial vasodilation slows isovolumic relaxation of the hypertrophied left ventricle.

1990 • 26 citations

Left ventricular pressure-length relation during exercise-induced ischemia

1989 • 24 citations

Cardiac mechanics and function in obese normotensive persons with normal coronary arteries

1987 • 24 citations

Left ventricular filling: relationship with arterial blood pressure, left ventricular mass, age, heart rate and body build

1991 • 24 citations

The apexcardiogram in ischemic heart disease.

1972 • 23 citations

The left atrial volume curve can be assessed from pulmonary vein and mitral valve velocity tracings

1994 • 21 citations

Noninvasive detection of exercise-induced markedly elevated left ventricular filling pressure by pulsed Doppler echocardiography in patients with coronary artery disease

1989 • 21 citations

Left ventricular systolic and diastolic function in the hypertrophied ventricle.

1990 • 18 citations

Myocardial relaxation in regionally stunned left ventricle

1996 • 17 citations

Relaxation and Diastolic Distensibility of the Regionally Ischemic Left Ventricle

1987 • 16 citations

A new approach to in situ left ventricular volume clamping in dogs

1991 • 16 citations

Reversal of constrictive/restrictive physiology with treatment of allograft rejection

1990 • 16 citations

Impact of age and gender on peak oxygen uptake in chronic heart failure

1997 • 14 citations

Paracrine coronary endothelial modulation of diastolic left ventricular function in man: Implications for diastolic heart failure

1996 • 14 citations

Influence of Pressure and Volume Overload on Diastolic Compliance

1987 • 12 citations

Abnormal Left Ventricular Diastolic Function during Cold Pressor Test in Uncomplicated Insulin-Dependent Diabetes Mellitus

1995 • 10 citations

Patterns of Diastolic Abnormalities during Isometric Stress in Patients with Systemic Hypertension

1997 • 9 citations

Relation between intraventricular pressure and volume in diastole.

1990 • 9 citations

Effects of Antihypertensive Therapy on Diastolic Dysfunction in Left Ventricular Hypertrophy

1992 • 9 citations

Ischemic and Nonischemic Patterns of Diastolic Abnormalities during Isometric Handgrip Exercise

1995 • 7 citations

Abnormal changes in transmitral flow after acute exposure to nitroglycerin and nifedipine in uncomplicated insulin-dependent diabetes mellitus: A Doppler echocardiographic study

1993 • 6 citations

Noninvasive detection of coronary artery disease by assessing diastolic abnormalities during low isometric exercise

1993 • 5 citations

Diastolic Dysfunction in Chronic Pressure and Volume Overload

1994 • 4 citations

Handgrip-apexcardiographic test: a new mode of detecting patients with silent exercise-induced myocardial ischemia.

1992 • 3 citations