A conserved domain regulates interactions of the v-fps protein-tyrosine kinase with the host cell.

PROTEIN-TYROSINE KINASES

1985 • 2,198 citations

A Noncatalytic Domain Conserved among Cytoplasmic Protein-Tyrosine Kinases Modifies the Kinase Function and Transforming Activity of Fujinami Sarcoma Virus P130^gag-fps

1986 • 478 citations

Transformation by Rous sarcoma virus: effects of src gene expression on the synthesis and phosphorylation of cellular polypeptides.

1979 • 293 citations

Four Different Classes of Retroviruses Induce Phosphorylation of Tyrosines Present in Similar Cellular Proteins

1981 • 178 citations

A strain of Fujinami sarcoma virus which is temperature-sensitive in protein phosphorylation and cellular transformation

1980 • 164 citations

Protein phosphorylation at tyrosine is induced by the v-erbB gene product in vivo and in vitro

1985 • 160 citations

Mutagenesis of Fujinami Sarcoma Virus: Evidence that tyrosine phosphorylation of P130gag-fps modulates its biological activity

1984 • 142 citations

Hormonal regulation of the rous sarcoma virus src gene via a heterologous promoter defines a threshold dose for cellular transformation

1984 • 132 citations

Identification of functional regions in the transforming protein of Fujinami sarcoma virus by in-phase insertion mutagenesis

1984 • 113 citations

Membrane association of a 36,000-dalton substrate for tyrosine phosphorylation in chicken embryo fibroblasts transformed by avian sarcoma viruses.

1983 • 89 citations

Phosphorylation of talin at tyrosine in Rous sarcoma virus-transformed cells.

1987 • 83 citations

Revertants of an ASV-transformed rat cell line have lost the complete provirus or sustained mutations insrc

1981 • 81 citations

A lysine in the ATP-binding site of P130gag-fps is essential for protein-tyrosine kinase activity.

1986 • 80 citations

Transformation-defective mutants of Rous sarcoma virus with src gene deletions of varying length

1977 • 78 citations

Amino Acid Alterations Within a Highly Conserved Region of the Rous Sarcoma Virus src Gene Product pp60^src Inactivate Tyrosine Protein Kinase Activity

1984 • 75 citations

Cytoplasmic localization of the transforming protein of Fujinami sarcoma virus: salt-sensitive association with subcellular components

1983 • 65 citations

Mapping of multiple phosphorylation sites within the structural and catalytic domains of the Fujinami avian sarcoma virus transforming protein

1983 • 59 citations

Genetic analysis of p60v-src domains involved in the induction of different cell transformation parameters

1986 • 58 citations

Enzymatic activation of Fujinami sarcoma virus gag-fps transforming proteins by autophosphorylation at tyrosine.

1987 • 43 citations

Complementation rescue of Rous sarcoma virus from transformed mammalian cells by polyethylene glycol-mediated cell fusion

1977 • 43 citations

Identification of an amino terminal domain required for the transforming activity of the Rous sarcoma virus src protein

1987 • 41 citations

Phosphorylation of Talin at Tyrosine in Rous Sarcoma Virus-Transformed Cells

1987 • 34 citations

Catalytic and non-catalytic domains of the Fujinami sarcoma virus P130gag-fps protein-tyrosine kinase distinguished by the expression of v-fps polypeptides in Escherichia coli.

1987 • 30 citations

Mutants of rous sarcoma virus with extensive deletions of the viral genome

1979 • 25 citations

Monoclonal antibodies to the transforming protein of Fujinami avian sarcoma virus discriminate between different fps-encoded proteins

1984 • 22 citations

Transformation parameters of chick embryo fibroblasts transformed by fujinami, PRCII, PRCII-p, and Y73 avian sarcoma viruses

1982 • 16 citations