The morphology but not the function of endosomes and lysosomes is altered by brefeldin A.

Brefeldin A: insights into the control of membrane traffic and organelle structure.

1992 • 1,848 citations

Rapid redistribution of Golgi proteins into the ER in cells treated with brefeldin A: Evidence for membrane cycling from Golgi to ER

1989 • 1,685 citations

The Biogenesis of Lysosomes

1989 • 1,583 citations

Molecular dissection of the secretory pathway

1992 • 985 citations

Microtubule-dependent retrograde transport of proteins into the ER in the presence of brefeldin a suggests an ER recycling pathway

1990 • 972 citations

Novel blockade by brefeldin A of intracellular transport of secretory proteins in cultured rat hepatocytes.

1986 • 847 citations

Brefeldin A's effects on endosomes, lysosomes, and the TGN suggest a general mechanism for regulating organelle structure and membrane traffic

1991 • 832 citations

Clathrin, Adaptors, and Sorting

1990 • 704 citations

Three-dimensional visualization of coated vesicle formation in fibroblasts.

1980 • 576 citations

Translocation and clustering of endosomes and lysosomes depends on microtubules.

1987 • 498 citations

Brefeldin A, a drug that blocks secretion, prevents the assembly of non-clathrin-coated buds on Golgi cisternae

1991 • 465 citations

Dissociation of a 110-kD peripheral membrane protein from the Golgi apparatus is an early event in brefeldin A action.

1990 • 384 citations

Brefeldin A causes a microtubule-mediated fusion of the trans-Golgi network and early endosomes

1991 • 378 citations

Recruitment of coat proteins onto Golgi membranes in intact and permeabilized cells: Effects of brefeldin A and G protein activators

1992 • 358 citations

Late endosomes derive from early endosomes by maturation

1991 • 311 citations

Microtubule- and motor-dependent fusion in vitro between apical and basolateral endocytic vesicles from MDCK cells

1990 • 299 citations

Phorbol esters and horseradish peroxidase stimulate pinocytosis and redirect the flow of pinocytosed fluid in macrophages.

1985 • 288 citations

A mutation that impairs the ability of lipoprotein receptors to localise in coated pits on the cell surface of human fibroblasts

1977 • 280 citations

Radial extension of macrophage tubular lysosomes supported by kinesin

1990 • 276 citations

Tubular lysosome morphology and distribution within macrophages depend on the integrity of cytoplasmic microtubules.

1987 • 270 citations

Selective inhibition of transcytosis by brefeldin A in MDCK cells

1991 • 254 citations

Lysosomal membrane dynamics: structure and interorganellar movement of a major lysosomal membrane glycoprotein.

1986 • 193 citations

Delivery of ligands from sorting endosomes to late endosomes occurs by maturation of sorting endosomes

1992 • 187 citations

Maturation models for endosome and lysosome biogenesis

1991 • 172 citations

The arguments for pre-existing early and late endosomes

1991 • 156 citations

PtK1 cells contain a nondiffusible, dominant factor that makes the Golgi apparatus resistant to brefeldin A.

1991 • 109 citations

100-kD proteins of Golgi- and trans-Golgi network-associated coated vesicles have related but distinct membrane binding properties

1992 • 109 citations

Chapter 25 Immunoperoxidase Methods for the Localization of Antigens in Cultured Cells and Tissue Sections by Electron Microscopy

1989 • 101 citations

Unusual lysosomes in aortic smooth muscle cells: presence in living and rapidly frozen cells.

1986 • 75 citations

The distribution of 215-kilodalton mannose 6-phosphate receptors within cis (heavy) and trans (light) Golgi subfractions varies in different cell types.

1987 • 52 citations

Microtubule depolymerization inhibits transport of cathepsin D from the Golgi apparatus to lysosomes

1990 • 47 citations

Effects of brefeldin A on the endocytic route. Redistribution of mannose 6-phosphate/insulin-like growth factor II receptors to the cell surface.

1991 • 41 citations

Endosomes can undergo an ATP-dependent density increase in the absence of dense lysosomes.

1990 • 29 citations

Biosynthesis of lysosomal enzymes in cells of the End3 complementation group conditionally defective in endosomal acidification

1991 • 20 citations

Tubular lysosomes and their drug reactivity in cultured resident macrophages and in cell-free medium

1990 • 8 citations