Multiplex Reverse Transcription-PCR Screening for EML4-ALK Fusion Transcripts

Identification of the transforming EML4–ALK fusion gene in non-small-cell lung cancer

2007 • 5,137 citations

Recurrent Fusion of TMPRSS2 and ETS Transcription Factor Genes in Prostate Cancer

2005 • 3,714 citations

Global Survey of Phosphotyrosine Signaling Identifies Oncogenic Kinases in Lung Cancer

2007 • 2,249 citations

Pathology and genetics of tumours of the lung , pleura, thymus and heart

2004 • 1,860 citations

The impact of translocations and gene fusions on cancer causation

2007 • 1,319 citations

Distinct classes of chromosomal rearrangements create oncogenic ETS gene fusions in prostate cancer

2007 • 829 citations

Detection of Anaplastic Lymphoma Kinase (ALK) and Nucleolar Protein Nucleophosmin (NPM)-ALK Proteins in Normal and Neoplastic Cells With the Monoclonal Antibody ALK1

1997 • 569 citations

EML4-ALK Fusion Is Linked to Histological Characteristics in a Subset of Lung Cancers

2008 • 465 citations

Identification of Novel Isoforms of theEML4-ALKTransforming Gene in Non–Small Cell Lung Cancer

2008 • 428 citations

Identification of NVP-TAE684, a potent, selective, and efficacious inhibitor of NPM-ALK

2006 • 370 citations

Fusion genes and rearranged genes as a linear function of chromosome aberrations in cancer

2004 • 358 citations

Applications of retrovirus-mediated expression cloning.

1996 • 339 citations

Translocations involving anaplastic lymphoma kinase (ALK)

2001 • 279 citations

Anaplastic lymphoma kinase proteins in growth control and cancer

2004 • 228 citations

Causes of oncogenic chromosomal translocation

2005 • 196 citations

Molecular Characterization of a New ALK Translocation Involving Moesin (MSN-ALK) in Anaplastic Large Cell Lymphoma

2001 • 160 citations

Non‐muscle myosin heavy chain (MYH9): A new partner fused to ALK in anaplastic large cell lymphoma

2003 • 132 citations

Differential effects of X-ALK fusion proteins on proliferation, transformation, and invasion properties of NIH3T3 cells

2004 • 127 citations

Applying the discovery of the Philadelphia chromosome

2007 • 115 citations

Anaplastic lymphoma kinase activity is essential for the proliferation and survival of anaplastic large-cell lymphoma cells

2005 • 109 citations

Inhibition of ALK enzymatic activity in T-cell lymphoma cells induces apoptosis and suppresses proliferation and STAT3 phosphorylation independently of Jak3

2005 • 68 citations

Unique Substrate Specificity of Anaplastic Lymphoma Kinase (ALK): Development of Phosphoacceptor Peptides for the Assay of ALK Activity

2005 • 64 citations