Uncovering subdominant cytotoxic T-lymphocyte responses in lymphocytic choriomeningitis virus-infected BALB/c mice

Allele-specific motifs revealed by sequencing of self-peptides eluted from MHC molecules

1991 • 2,447 citations

MHC ligands and peptide motifs: first listing

1995 • 1,674 citations

Virus persistence in acutely infected immunocompetent mice by exhaustion of antiviral cytotoxic effector T cells

1993 • 1,219 citations

Selection of genetic variants of lymphocytic choriomeningitis virus in spleens of persistently infected mice. Role in suppression of cytotoxic T lymphocyte response and viral persistence.

1984 • 782 citations

Isolation and analysis of naturally processed viral peptides as recognized by cytotoxic T cells

1990 • 775 citations

Cytotoxic T-cell memory without antigen

1994 • 669 citations

Prominent role of secondary anchor residues in peptide binding to HLA-A2.1 molecules

1993 • 630 citations

Biology of cloned cytotoxic T lymphocytes specific for lymphocytic choriomeningitis virus: clearance of virus in vivo

1984 • 296 citations

Virus-induced immunosuppression: immune system-mediated destruction of virus-infected dendritic cells results in generalized immune suppression

1995 • 289 citations

Peptide binding to the most frequent HLA-A class I alleles measured by quantitative molecular binding assays

1994 • 233 citations

Analysis of cytotoxic T cell responses to dominant and subdominant epitopes during acute and chronic lymphocytic choriomeningitis virus infection.

1996 • 189 citations

Mechanism of recovery from acute virus infection: treatment of lymphocytic choriomeningitis virus-infected mice with monoclonal antibodies reveals that Lyt-2+ T lymphocytes mediate clearance of virus and regulate the antiviral antibody response

1987 • 185 citations

Molecular determinants of macrophage tropism and viral persistence: importance of single amino acid changes in the polymerase and glycoprotein of lymphocytic choriomeningitis virus

1993 • 185 citations

Identification of the class I genes of the mouse major histocompatibility complex by DNA-mediated gene transfer

1982 • 156 citations

Organ-specific selection of viral variants during chronic infection.

1988 • 148 citations

Molecular analyses of a five-amino-acid cytotoxic T-lymphocyte (CTL) epitope: an immunodominant region which induces nonreciprocal CTL cross-reactivity

1989 • 138 citations

Organization and evolution of D region class I genes in the mouse major histocompatibility complex.

1986 • 116 citations

H-2Dd exploits a four residue peptide binding motif.

1993 • 98 citations

Virus-Induced Immunosuppression

1993 • 93 citations

Thymic selection and adaptability of cytotoxic T lymphocyte responses in transgenic mice expressing a viral protein in the thymus.

1994 • 89 citations

Molecular basis of organ-specific selection of viral variants during chronic infection

1991 • 83 citations

Immune therapy of a persistent and disseminated viral infection

1987 • 77 citations

Effective clearance of a persistent viral infection requires cooperation between virus-specific Lyt2+ T cells and nonspecific bone marrow-derived cells

1987 • 76 citations

Persistent and slow virus infections

1971 • 76 citations

BALB/c-H-2 db : A newH-2 mutant in BALB/cKh that identifies a locus associated with theD region

1977 • 75 citations

Product of a transferred H–2Ld gene acts as restriction element for LCMV-specific killer T cells

1982 • 67 citations

Major histocompatibility complex binding and T cell recognition of a viral nonapeptide containing a minimal tetrapeptide

1991 • 64 citations

Molecular studies of murine mutant BALB/c-H-2dm2 define a deletion of several class I genes including the entire H-2Ld gene.

1986 • 53 citations

In vivo selection of lymphocyte-tropic and macrophage-tropic variants of lymphocytic choriomeningitis virus during persistent infection

1990 • 50 citations

MHC class I and non-MHC-linked capacity for generating an anti-viral CTL response determines susceptibility to CTL exhaustion and establishment of virus persistence in mice.

1994 • 49 citations

Consequences of a single Ir-gene defect for the pathogenesis of lymphocytic choriomeningitis

1985 • 41 citations

Control of acute infection with lymphocytic choriomeningitis virus in mice that cannot present an immunodominant viral cytotoxic T lymphocyte epitope.

1992 • 39 citations