The N-terminal CUB-Epidermal Growth Factor Module Pair of Human Complement Protease C1r Binds Ca2+ with High Affinity and Mediates Ca2+-dependent Interaction with C1s

Spectroscopic Determination of Tryptophan and Tyrosine in Proteins^*

1967 • 3,423 citations

The CUB Domain

1993 • 564 citations

The Classical Complement Pathway: Activation and Regulation of the First Complement Component

1985 • 514 citations

The Baculovirus Expression System: A Laboratory Guide

1993 • 404 citations

Epidermal growth factor-like modules

1993 • 343 citations

The Baculovirus Expression System

1992 • 337 citations

Complement system proteins which interact with C3b or C4b A superfamily of structurally related proteins

1986 • 195 citations

Activation of the First Component of Complement

1987 • 160 citations

Differential elution of Clq, Cl̄r and Cl̄s from human CT bound to immune aggregates. use in the rapid purification of Cl̄ sub-components

1979 • 141 citations

Cloning and sequencing of full-length cDNA encoding the precursor of human complement component C1r

1986 • 100 citations

Analysis of the Factor VIIa Binding Site on Human Tissue Factor: Effects of Tissue Factor Mutations on the Kinetics and Thermodynamics of Binding

1995 • 83 citations

Skeletal muscle ATP-sensitive K+ channels recorded from sarcolemmal blebs of split fibers: ATP inhibition is reduced by magnesium and ADP

1991 • 82 citations

Baculovirus-mediated Expression of Truncated Modular Fragments from the Catalytic Region of Human Complement Serine Protease C1s

1998 • 80 citations

The Relative Orientation of Gla and EGF Domains in Coagulation Factor X Is Altered by Ca²⁺ Binding to the First EGF Domain. A Combined NMR−Small Angle X-ray Scattering Study^,

1996 • 79 citations

Calcium-Dependent Binding of Recoverin to Membranes Monitored by Surface Plasmon Resonance Spectroscopy in Real Time

1997 • 76 citations

Preference of calcium‐dependent interactions between calmodulin‐like domains of calpain and calpastatin subdomains

1995 • 74 citations

Ca2+ binding properties and Ca2(+)-dependent interactions of the isolated NH2-terminal alpha fragments of human complement proteases C1-r and C1-s.

1990 • 72 citations

Analysis of calcium-dependent interaction between amino-terminal conserved region of calpastatin functional domain and calmodulin-like domain of mu-calpain large subunit.

1994 • 65 citations

Amino-terminal calcium-binding domain of human complement C1.hivin.s mediates the interaction of C1.hivin.r with C1q

1990 • 61 citations

The Human Complement System in Health and Disease.

1998 • 51 citations

Solution Structure of the Epidermal Growth Factor (EGF)-like Module of Human Complement Protease C1r, an Atypical Member of the EGF Family

1998 • 48 citations

Molecular characterization of the catalytic domains of human complement serine protease C.hivin.1r

1986 • 46 citations

Structure and Assembly of the Catalytic Region of Human Complement Protease C1̄r: A Three-Dimensional Model Based on Chemical Cross-Linking and Homology Modeling

1997 • 46 citations

Chemical and functional characterization of a fragment of C1s containing the epidermal growth factor homology region

1990 • 46 citations

Structure of the catalytic region of human complement protease C.hivin.1s: Study by chemical crosslinking and three-dimensional homology modeling

1995 • 45 citations

Recombinant human complement subcomponent C1s lacking .beta.-hydroxyasparagine, sialic acid, and one of its two carbohydrate chains still reassembles with C1q and C1r to form a functional C1 complex

1992 • 40 citations

Activation of human complement serine-proteinase C1r is down-regulated by a Ca2+-dependent intramolecular control that is released in the C1 complex through a signal transmitted by C1q

1994 • 34 citations

Ca2+ Binding to the First Epidermal Growth Factor Module of Coagulation Factor VIIa Is Important for Cofactor Interaction and Proteolytic Function

1997 • 33 citations

Expression of Hemolytically Active Human Complement Component Clr Proenzyme in Insect Cells Using a Baculovirus Vector

1989 • 30 citations

Analysis of the N‐linked oligosaccharides of human C1s using electrospray ionisation mass spectrometry

1995 • 28 citations

Domain structure, stability, and interactions of human complement C1.lovin.s: characterization of a derivative lacking most of the B chain

1988 • 27 citations

Calcium-sensitive thermal transitions and domain structure of human complement subcomponent C1.hivin.r

1987 • 27 citations

Ca2+ Binding to the First Epidermal Growth Factor-like Domain of Factor VIIa Increases Amidolytic Activity and Tissue Factor Affinity

1997 • 25 citations

Calcium-dependent interactions between Gla and EGF domains in human coagulation factor IX

1994 • 24 citations

Chemical synthesis and characterization of the epidermal growth factor‐like module of human complement protease Clr

1997 • 21 citations

Ca2+-Linked Association of Human Complement C1s.hivin. and C1r.hivin.

1994 • 20 citations

Expression and characterization of a 159 amino acid, N-terminal fragment of human complement component Cls

1997 • 18 citations

Functional effects of domain deletions in a multidomain serine protease, Clr

1996 • 15 citations

Effect of lactoperoxidase-catalyzed iodination on the calcium-dependent interactions of human C.hivin.1s. Location of the iodination sites

1991 • 14 citations

Differential accessibility of the carbohydrate moieties of C.hivin.1s-C.hivin.1r-C.hivin.1r-C.hivin.1s, the catalytic subunit of human C.hivin.1

1988 • 11 citations

The Production and Purification of Functional Decorin in a Baculovirus System

1997 • 10 citations