Physical Chemical Studies of the Structure and Function of Dna Binding (Helix-Destabilizing) Proteins

Prediction of protein conformation

1974 • 3,327 citations

Transfer of proteins across membranes. I. Presence of proteolytically processed and unprocessed nascent immunoglobulin light chains on membrane-bound ribosomes of murine myeloma.

1975 • 3,026 citations

Structure of Chromatin

1977 • 1,276 citations

DNA gyrase: an enzyme that introduces superhelical turns into DNA.

1976 • 1,175 citations

Sequence-specific recognition of double helical nucleic acids by proteins.

1976 • 1,123 citations

Chemical Modification of Proteins

2012 • 1,097 citations

β-turns in proteins

1977 • 960 citations

[11] DNA-cellulose chromatography

1971 • 842 citations

Physiological Studies of Conditional Lethal Mutants of Bacteriophage T4D

1963 • 808 citations

T4 Bacteriophage Gene 32: A Structural Protein in the Replication and Recombination of DNA

1970 • 793 citations

Interaction between DNA and an Escherichia coli protein ω

1971 • 749 citations

Enzymatic Synthesis of Deoxyribonucleic Acid

1962 • 621 citations

Genetic Regulation: The Lac Control Region

1975 • 523 citations

The Nucleotide Sequence of the lac Operator

1973 • 480 citations

Filamentous bacterial viruses

1969 • 454 citations

Restriction Endonuclease

1976 • 405 citations

A DNA-Unwinding Protein Isolated from Escherichia coli: Its Interaction with DNA and with DNA Polymerases

1972 • 355 citations

The deoxyribonucleic acid unwinding protein of Escherichia coli. Properties and functions in replication.

1975 • 322 citations

Studies with DNA-cellulose Chromatography. I. DNA-binding Proteins from Escherichia coli

1968 • 320 citations

Isolation and characterization of gene 5 protein of filamentous bacterial viruses

1972 • 292 citations

Characterization by electron microscopy of the complex formed between T4 bacteriophage gene 32-protein and DNA

1972 • 256 citations

Interpretation of monovalent and divalent cation effects on the lac repressor-operator interaction

1977 • 251 citations

DNA-binding Proteins specific for Cells infected by Adenovirus

1973 • 247 citations

Crystallization of proteins from polyethylene glycol.

1976 • 242 citations

Stimulation of T4 bacteriophage DNA polymerase by the protein product of T4 gene 32

1971 • 230 citations

A mechanism of duplex DNA replication revealed by enzymatic studies of phage phi X174: catalytic strand separation in advance of replication.

1977 • 223 citations

Multienzyme Systems of DNA Replication

1974 • 222 citations

Lac Repressor

1973 • 215 citations

Fluorotyrosine alkaline phosphatase: Internal mobility of individual tyrosines and the role of chemical shift anisotropy as a 19F nuclear spin relaxation mechanism in proteins

1975 • 213 citations

Purification and physical characterization of nucleic acid helix-unwinding proteins from calf thymus.

1976 • 211 citations

Detection of prokaryotic signal peptidase in an Escherichia coli membrane fraction: endoproteolytic cleavage of nascent f1 pre-coat protein.

1978 • 209 citations

DNA "melting" proteins. II. Effects of bacteriophage T4 gene 32-protein binding on the conformation and stability of nucleic acid structures.

1976 • 206 citations

Micrococcus luteus DNA gyrase: active components and a model for its supercoiling of DNA.

1978 • 206 citations

Conversion of the M13 Viral Single Strand to the Double-stranded Replicative Forms by Purified Proteins

1974 • 202 citations

Recent excitement in the DNA replication problem

1977 • 193 citations

DNA "melting" proteins. IV. Fluorescence measurements of binding parameters for bacteriophage T4 gene 32-protein to mono-, oligo-, and polynucleotides.

1976 • 192 citations

Filamentous bacterial viruses.

1969 • 185 citations

Ring‐current effects in the nmr of nucleic acids: A graphical approach

1976 • 177 citations

Properties of the isolated gene 5 protein of bacteriophage fd

1972 • 165 citations

The structural gene for deoxyribonucleic acid polymerase in bacteriophages T4 and T5.

1965 • 157 citations

Role of coliphage M13 gene 5 in single-stranded DNA production

1971 • 149 citations

Chemical Modification of Proteins

1976 • 146 citations

Circular dichroism and ultraviolet absorption of a deoxyribonucleic acid binding protein of filamentous bacteriophage

1973 • 143 citations

The Amino-Acid Sequence of lac Repressor

1973 • 143 citations

Coupling of late transcription to viral replication in bacteriophage T4 development

1970 • 143 citations

Ten proteins required for conversion of phiX174 single-stranded DNA to duplex form in vitro. Resolution and reconstitution.

1975 • 141 citations

Dominance interactions in Escherichia coli cells mixedly infected with bacteriophage T4D wild-type and amber mutants and their possible implications as to type of gene-product function: Catalytic vs. stoichiometric

1968 • 138 citations

Reinvestigation of a region of the fd bacteriophage coat protein sequence

1974 • 136 citations

The RNA primer synthesized by primase to initiate phage G4 DNA replication.

1978 • 136 citations

Deoxyribonucleic Acid Polymerase of Bacteriophage T7

1971 • 132 citations

Filamentous bacterial viruses

1974 • 132 citations

Incorporation of uracil-14C into nucleic acids in Escherichia coli infected with bacteriophage T4 and T4 amber mutants

1967 • 131 citations

Structure and assembly of filamentous bacterial viruses

1975 • 129 citations

Molecular mechanisms of genetic recombination in bacteriophage

1966 • 129 citations

Fluorine-19 nuclear magnetic resonance study of fluorotyrosine alkaline phosphatase: the influence of zinc on protein structure and a conformational change induced by phosphate binding

1976 • 126 citations

Purification and Properties of the Escherichia coli Deoxyribonucleic Acid-unwinding Protein

1974 • 124 citations

Chemical modifications of functional residues of fd gene 5 DNA-binding protein

1975 • 124 citations

Chromosomal Proteins and their Role in the Regulation of Gene Expression

1975 • 120 citations

Starting and Stopping Sequences for the RNA Polymerase

1976 • 119 citations

Complex of bacteriophage M13 single-stranded DNA and gene 5 protein

1974 • 119 citations

Proteins binding to DNA and their Relation to Growth in Cultured Mammalian Cells

1971 • 117 citations

X-ray diffraction and electron microscope studies on the structure of the small filamentous bacteriophage fd

1966 • 112 citations

Nucleic acid helix-coil transitions mediated by helix-unwinding proteins from calf thymus.

1976 • 109 citations

Single-stranded DNA structure and DNA polymerase activity in the presence of nucleic acid helix-unwinding proteins from calf thymus.

1976 • 109 citations

Asymmetric orientation of phage M13 coat protein in Escherichia coli cytoplasmic membranes and in synthetic lipid vesicles.

1976 • 108 citations

Physicochemical properties of DNA binding proteins. Gene 32 protein of T4 and Escherichia coli unwinding protein

1975 • 106 citations

Evidence for a major conformational change of coat protein in assembly of fl bacteriophage

1976 • 99 citations

Catalysis of DNA reassociation by the Escherichia coli DNA binding protein

1977 • 92 citations

An RNA transcribed from DNA at the origin of phage fd single strand to replicative form conversion.

1978 • 91 citations

Deoxyribonucleic acid synthesis in Escherichia coli infected with some deoxyribonucleic acid polymerase-less mutants of bacteriophage T4

1966 • 91 citations

Molecular Recombination in T4 Bacteriophage Deoxyribonucleic Acid II. Single-Strand Breaks and Exposure of Uncomplemented Areas as a Prerequisite for Recombination

1967 • 91 citations

Studies on a mammalian cell protein (P8) with affinity for DNA in vitro

1973 • 89 citations

Regulation of coliphage f1 single-stranded DNA synthesis by a DNA-binding protein

1973 • 88 citations

Proteins Made in the Mammalian Cell Cycle

1971 • 87 citations

DNA "melting" proteins. III. Fluorescence "mapping" of the nucleic acid binding site of bacteriophage T4 gene 32-protein.

1976 • 85 citations

A Single-Strand-Specific DNA-Binding Protein from Mouse Cells that Stimulates DNA Polymerase.. Its Modification by Phosphorylation

1977 • 84 citations

Gene V protein of fd bacteriophage. Dimer formation and the role of tyrosyl groups in DNA binding.

1975 • 81 citations

Filamentous bacterial viruses

1974 • 80 citations

The amino acid sequence of a DNA binding protein, the gene 5 product of fd filamentous bacteriophage

1974 • 79 citations

A DNA-binding protein in meiotic cells of Lilium

1971 • 78 citations

T7 RNA polymerase: promoter structure and polymerase binding

1979 • 78 citations

Primary structure and sidechain interactions of PFL filamentous bacterial virus coat protein

1975 • 77 citations

Requirement of a Functional Gene 32 Product of Bacteriophage T4 in UV Repair

1973 • 77 citations

A DNA-Binding Protein Induced by Bacteriophage T7

1973 • 74 citations

Conformational states of a hydrophobic protein. The coat protein of fd bacteriophage

1978 • 73 citations

Structure of gene 5 protein-oligodeoxynucleotide complexes as determined by proton, ¹⁹F, and ³¹P nuclear magnetic resonance

1976 • 72 citations

Gene 5 protein of bacteriophage fd: A dimer which interacts Co-operatively with DNA

1976 • 71 citations

Stimulation of T7 DNA polymerase by a new phage-coded protein

1973 • 70 citations

T4 gene 32 protein model for control of activity at replication fork

1976 • 66 citations

A deoxyribonucleic acid unwinding protein isolated from regenerating rat liver. Physical and functional properties.

1978 • 66 citations

Structure of a promoter for T7 RNA polymerase.

1977 • 66 citations

Structural changes in the T4 gene 32 protein induced by DNA polynucleotides.

1978 • 66 citations

Studies of the self-association of bacteriophage T4 gene 32 protein by equilibrium sedimentation

1975 • 65 citations

The isolation and properties of a DNA-unwinding protein from Ustilago maydis

1975 • 64 citations

Molecular weight of single-stranded fd bacteriophage DNA. High speed equilibrium sedimentation and light scattering measurements

1974 • 63 citations

The amino acid sequence of gene 5 protein of bacteriophage M 13

1974 • 63 citations

A Deoxyribonucleic Acid-Binding Protein Induced by Bacteriophage T7

1974 • 60 citations

Studies on DNA Unwinding

1977 • 59 citations

Meiotic Protein in Spermatocytes of Mammals

1971 • 55 citations

A DNA fragment from the origin of single-strand to double-strand DNA replication of bacteriophage fd.

1976 • 55 citations

Adenovirus DNA replication. III. DNA binding proteins in the cytoplasm and in a nuclear membrane complex isolated from uninfected and adenovirus 2 infected cells

1975 • 53 citations

Tyrosyl-base-phenylalanyl intercalation in gene 5 protein-DNA complexes: proton nuclear magnetic resonance of selectively deuterated gene 5 protein

1978 • 46 citations

Denaturation of T4 DNA by an in vitro processed gene 32‐protein

1974 • 44 citations

Iodination of Escherichia coli lac repressor. Effect of tyrosine modification on repressor activity

1975 • 42 citations

Interaction of RNA Polymerase with the DNA Template

1976 • 41 citations

T7 RNA polymerase. Conformation, functional groups, and promoter binding

1975 • 39 citations

Photo-induced cross-linkage of gene-5 protein and bacteriophage fd DNA⁺

1975 • 39 citations

DNA-binding proteins in young and senescent normal human fibroblasts

1975 • 37 citations

The existence of random coil N‐terminal peptides — ‘tails’ — in native histone complexes

1976 • 37 citations

Study of Intracellular Collagen Precursors using DNA-Cellulose Chromatography

1972 • 36 citations

Function of gene 32-protein, a new protein essential for the genetic recombination and replication of T4 bacteriophage DNA.

1970 • 35 citations

Self-Association of Gene-32 Protein of Bacteriophage T4

1972 • 34 citations

Evidence for a structural change in the substrate preceding hydrolysis of a chymotrypsin acyl enzyme: Application of the resonance Raman labelling technique to a dynamic biochemical system

1976 • 30 citations

Replication of Bacteriophage M‐13

1973 • 28 citations

Circular dichroism study of the interaction between T4 gene 32 protein and polynucleotides

1978 • 28 citations

Synthesis of DNA-binding proteins during the cell cycle of WI-38 cells

1974 • 25 citations

Investigation of the conformational and self-aggregational processes of histones using hydrogen and carbon-13 nuclear magnetic resonance

1975 • 25 citations

Synthesis of DNA-binding protein in WI-38 cells stimulated to synthesize DNA by medium replacement

1974 • 24 citations

Oligonucleotides and the quaternary structure of gene‐5 protein from filamentous bacteriophage

1974 • 22 citations

Some properties of a DNA-unwinding protein unique to lymphocytes from chronic lymphocytic leukemia.

1975 • 20 citations

A phosphorylatable DNA-binding protein associated with a lipoprotein fraction from rat spermatocyte nuclei*1

1977 • 19 citations

DNA unwinding component of the nonhistone chromatin proteins.

1976 • 17 citations

DNA binding site of the helix destabilizing protein gp32 from bacteriophage T4

1978 • 13 citations

A comparison of DNA binding proteins from normal and virus‐transformed mouse cells

1973 • 11 citations

Molecular Approaches to the Interaction of Nucleic Acids with “Melting” Proteins

1977 • 11 citations

In Vitro DNA Replication Catalyzed by Six Purified T4 Bacteriophage Proteins

1977 • 10 citations

Gene-V Product of Bacteriophage fd: Structure of a DNA-unwinding Protein and Its Complexes with DNA

1979 • 8 citations

Partial purification and properties of a DNA-binding protein from nuclei of cells infected with polyoma virus

1976 • 8 citations

Chromosomal proteins and their role in the regulation of gene expression : proceedings of the Florida Colloquium on Molecular Biology, March 13-14, 1975

1975 • 8 citations

Bacteriophage T4D-induced proteinase

1974 • 7 citations

Plasmids and phages

1977 • 5 citations

Isolation and characterization of a DNA-binding non-histone protein from Tetrahymena pyriformis

1975 • 5 citations

Species-specific cellular DNA-binding proteins expressed in mouse cells transformed by chemical carcinogens.

1978 • 4 citations

Synthesis of A DNA binding protein in normal and transformed cells

1974 • 3 citations