Vaccination with recombinant heat shock protein 60 from Histoplasma capsulatum protects mice against pulmonary histoplasmosis

A Rapid and Sensitive Method for the Quantitation of Microgram Quantities of Protein Utilizing the Principle of Protein-Dye Binding

1976 • 225,752 citations

Single-Step Method of RNA Isolation by Acid Guanidinium Thiocyanate–Phenol–Chloroform Extraction

1987 • 64,270 citations

Sequence from picomole quantities of proteins electroblotted onto polyvinylidene difluoride membranes.

1987 • 5,066 citations

Protein folding in the cell

1992 • 4,138 citations

Heat shock proteins and the immune response

1990 • 944 citations

Polypeptide chain binding proteins: Catalysts of protein folding and related processes in cells

1989 • 884 citations

Cloning of the mycobacterial epitope recognized by T lymphocytes in adjuvant arthritis

1988 • 838 citations

Identification, developmental regulation, and response to heat shock of two antigenically related forms of a major nuclear envelope protein in Drosophila embryos: application of an improved method for affinity purification of antibodies using polypeptides immobilized on nitrocellulose blots

1984 • 668 citations

Stress proteins, infection, and immune surveillance

1989 • 477 citations

Stress proteins are immune targets in leprosy and tuberculosis.

1988 • 446 citations

Vaccination against autoimmune mouse diabetes with a T-cell epitope of the human 65-kDa heat shock protein.

1991 • 384 citations

Chlamydial disease pathogenesis. The 57-kD chlamydial hypersensitivity antigen is a stress response protein.

1989 • 334 citations

SYNOVIAL FLUID T CELL REACTIVITY AGAINST 65 kD HEAT SHOCK PROTEIN OF MYCOBACTERIA IN EARLY CHRONIC ARTHRITIS

1988 • 311 citations

T lymphocytes from healthy individuals with specificity to self-epitopes shared by the mycobacterial and human 65-kilodalton heat shock protein.

1989 • 237 citations

Antifolding activity of hsp60 couples protein import into the mitochondrial matrix with export to the intermembrane space

1992 • 233 citations

Enumeration of T cells reactive with Mycobacterium tuberculosis organisms and specific for the recombinant mycobacterial 64‐kDa protein

1987 • 216 citations

Protection against streptococcal cell wall-induced arthritis by pretreatment with the 65-kD mycobacterial heat shock protein.

1989 • 211 citations

A mycobacterial 65-kD heat shock protein induces antigen-specific suppression of adjuvant arthritis, but is not itself arthritogenic.

1990 • 188 citations

Recognition of a mycobacteria-specific epitope in the 65-kD heat-shock protein by synovial fluid-derived T cell clones.

1990 • 168 citations

Antigenic relatedness of a strongly immunogenic 65 kDA mycobacterial protein antigen with a similarly sized ubiquitous bacterial common antigen

1988 • 152 citations

Mapping of T cell epitopes using recombinant antigens and synthetic peptides.

1987 • 152 citations

Mycobacterium tuberculosis expresses two chaperonin-60 homologs.

1993 • 135 citations

Molecular cloning of a Chinese hamster mitochondrial protein related to the “chaperonin” family of bacterial and plant proteins

1989 • 99 citations

Immunochemical characterization of a protein associated with Mycobacterium leprae cell wall

1985 • 87 citations

Major cytoplasmic membrane protein of Legionella pneumophila, a genus common antigen and member of the hsp 60 family of heat shock proteins, induces protective immunity in a guinea pig model of Legionnaires' disease.

1993 • 81 citations

7 Stress Proteins and Infectious Diseases

1990 • 81 citations

Protective efficacy of a 62-kilodalton antigen, HIS-62, from the cell wall and cell membrane of Histoplasma capsulatum yeast cells

1991 • 78 citations

Antigenicity and immunogenicity of an extract from the cell wall and cell membrane of Histoplasma capsulatum yeast cells

1991 • 54 citations

Prevention of adjuvant arthritis in rats by a nonapeptide from the 65-kD mycobacterial heat-shock protein

1990 • 50 citations

Heterologous expression of the 65-kilodalton antigen of Mycobacterium leprae and murine T-cell responses to the gene product

1988 • 41 citations

Recognition of Histoplasma capsulatum yeast-cell antigens by human lymphocytes and human T-cell clones

1992 • 11 citations