Detection and identification of single molecules in solution

Optical detection and spectroscopy of single molecules in a solid

1989 • 1,198 citations

Fluorescence Microscopy: Reduced Photobleaching of Rhodamine and Fluorescein Protein Conjugates by n -Propyl Gallate

1982 • 851 citations

Subattomole Amino Acid Analysis by Capillary Zone Electrophoresis and Laser-Induced Fluorescence

1988 • 510 citations

Detection of single fluorescent molecules

1990 • 473 citations

Optical microscopic observation of single small molecules

1976 • 279 citations

High-sensitivity fluorescence detector for fluorescein isothiocyanate derivatives of amino acids separated by capillary zone electrophoresis

1989 • 256 citations

Single-molecule fluorescence detection: autocorrelation criterion and experimental realization with phycoerythrin.

1989 • 172 citations

A demonstration of one-atom detection

1977 • 171 citations

Quantum efficiency independence of the time integrated emission from a fluorescent molecule

1976 • 169 citations

Laser-induced fluorescence of flowing samples as an approach to single-molecule detection in liquids

1984 • 161 citations

High-Speed DNA Sequencing: An Approach Based Upon Fluorescence Detection of Single Molecules

1989 • 156 citations

Attogram Detection Limit for Aqueous Dye Samples by Laser-Induced Fluorescence

1983 • 143 citations

Single-molecule detection of Rhodamine 6G in ethanolic solutions using continuous wave laser excitation

1991 • 124 citations

Single-molecule detection limits in levitated microdroplets

1991 • 105 citations

Sub-picoliter detection with the sheath flow cuvette

1985 • 100 citations

Interaction of capillary zone electrophoresis with a sheath flow cuvette detector

1990 • 98 citations

Rapid DNA sequencing based upon single molecule detection

1991 • 65 citations

Ultrasensitive laser-induced fluorescence detection in hydrodynamically focused flows

1987 • 52 citations

A method for improving light collection by 600% from square cross section flow cytometry chambers

1985 • 34 citations

Molecular calibration in flow cytometry with sub-attogram detection limit

1986 • 23 citations

Laser-Induced Fluorescence Detection of Rhodamine-6G at 6 × 10⁻¹⁵ M

1991 • 16 citations