Characterization of the Mycobacterium tuberculosis H37Rv alkyl hydroperoxidase AhpC points to the importance of ionic interactions in oligomerization and activity

Basic local alignment search tool

1990 • 87,358 citations

MOLSCRIPT: a program to produce both detailed and schematic plots of protein structures

1991 • 14,222 citations

Basic Local Alignment Search Tool

1990 • 12,947 citations

Improved methods for building protein models in electron density maps and the location of errors in these models

1991 • 12,831 citations

Deciphering the biology of Mycobacterium tuberculosis from the complete genome sequence

1998 • 7,572 citations

CLUSTAL: a package for performing multiple sequence alignment on a microcomputer

1988 • 3,446 citations

The catalase—peroxidase gene and isoniazid resistance of Mycobacterium tuberculosis

1992 • 1,287 citations

Ellman's reagent: 5,5′-dithiobis(2-nitrobenzoic acid)—a reexamination

1979 • 997 citations

Thioredoxin-dependent peroxide reductase from yeast.

1994 • 940 citations

Hepatic Microsomal Ethanol Oxidation

1972 • 603 citations

Deciphering the biology of Mycobacterium tuberculosis from the complete genome sequence

1998 • 542 citations

Characterization of a Mammalian Peroxiredoxin That Contains One Conserved Cysteine

1998 • 439 citations

Compensatory ahp C Gene Expression in Isoniazid-Resistant Mycobacterium tuberculosis

1996 • 422 citations

OxyR, a positive regulator of hydrogen peroxide-inducible genes in Escherichia coli and Salmonella typhimurium, is homologous to a family of bacterial regulatory proteins.

1989 • 415 citations

An Alkyl Hydroperoxide Reductase from Salmonella typhimurium Involved in the Defense of DNA against Oxidative Damage

1989 • 337 citations

Crystal structure of decameric 2-Cys peroxiredoxin from human erythrocytes at 1.7Å resolution

2000 • 296 citations

An alkyl hydroperoxide reductase induced by oxidative stress in Salmonella typhimurium and Escherichia coli: genetic characterization and cloning of ahp

1989 • 261 citations

Crystal structure of a multifunctional 2-Cys peroxiredoxin heme-binding protein 23 kDa/proliferation-associated gene product

1999 • 255 citations

Roles for the Two Cysteine Residues of AhpC in Catalysis of Peroxide Reduction by Alkyl Hydroperoxide Reductase from Salmonella typhimurium

1997 • 182 citations

Mycobacterium tuberculosis is a natural mutant with an inactivated oxidative‐stress regulatory gene:implications for sensitivity to isoniazid

1995 • 181 citations

General and oxidative stress responses in Bacillus subtilis: cloning, expression, and mutation of the alkyl hydroperoxide reductase operon

1996 • 149 citations

ahpC, a gene involved in isoniazid resistance of the Mycobacterium tuberculosis complex

1996 • 148 citations

[51] Bifunctional reagents

1983 • 146 citations

The AhpC and AhpD Antioxidant Defense System of Mycobacterium tuberculosis

2000 • 137 citations

Glutathione-Linked Thiol Peroxidase Activity of Human Serum Albumin: A Possible Antioxidant Role of Serum Albumin in Blood Plasma

1996 • 119 citations

Oxidative stress response and its role in sensitivity to isoniazid in mycobacteria: characterization and inducibility of ahpC by peroxides in Mycobacterium smegmatis and lack of expression in M. aurum and M. tuberculosis

1996 • 115 citations

Antisense RNA to ahpC, an oxidative stress defence gene involved in isoniazid resistance, indicates that AhpC of Mycobacterium bovis has virulence properties

1998 • 109 citations

Biosynthesis of mycothiol: elucidation of the sequence of steps in Mycobacterium smegmatis

1997 • 80 citations

Stimulation of Peroxidase Activity by Decamerization Related to Ionic Strength: AhpC Protein from Amphibacillus xylanus

1999 • 59 citations

[26] Chemical cross-linking of histones

1989 • 34 citations

Reaction Mechanism of Amphibacillus xylanus NADH Oxidase/Alkyl Hydroperoxide Reductase Flavoprotein

1996 • 33 citations