Homologous recombination in plant cells after Agrobacterium-mediated transformation.

A Revised Medium for Rapid Growth and Bio Assays with Tobacco Tissue Cultures

1962 • 66,242 citations

Rapid and efficient site-specific mutagenesis without phenotypic selection.

1985 • 7,573 citations

Replication of an origin-containing derivative of plasmid RK2 dependent on a plasmid function provided in trans

1979 • 3,210 citations

Introduction of a Chimeric Chalcone Synthase Gene into Petunia Results in Reversible Co-Suppression of Homologous Genes in trans.

1990 • 2,386 citations

Site-directed mutagenesis by gene targeting in mouse embryo-derived stem cells

1987 • 2,368 citations

Transformation of yeast.

1978 • 2,267 citations

A binary plant vector strategy based on separation of vir- and T-region of the Agrobacterium tumefaciens Ti-plasmid

1983 • 1,758 citations

Disruption of the proto-oncogene int-2 in mouse embryo-derived stem cells: a general strategy for targeting mutations to non-selectable genes

1988 • 1,690 citations

Disruption of the Dictyostelium Myosin Heavy Chain Gene by Homologous Recombination

1987 • 984 citations

Insertion of DNA sequences into the human chromosomal β-globin locus by homologous recombination

1985 • 978 citations

High frequency targeting of genes to specific sites in the mammalian genome

1986 • 619 citations

Reversible methylation and inactivation of marker genes in sequentially transformed tobacco plants

1989 • 544 citations

The sulfonylurea herbicide sulfometuron methyl is an extremely potent and selective inhibitor of acetolactate synthase in Salmonella typhimurium.

1984 • 387 citations

Gene targeting in plants

1988 • 370 citations

BASIC PROCESSES UNDERLYING AGROBACTERIUM-MEDIATED DNA TRANSFER TO PLANT CELLS

1988 • 289 citations

The molecular basis of sulfonylurea herbicide resistance in tobacco

1988 • 276 citations

Rapid and Efficient Site-Specific Mutagenesis without Phenotypic Selection

1989 • 233 citations

Targeted mutation of the Hprt gene in mouse embryonic stem cells.

1988 • 226 citations

A chimaeric hygromycin resistance gene as a selectable marker in plant cells

1985 • 209 citations

Recombinant fragment assay for gene targetting based on the polymerase chain reaction

1988 • 192 citations

Homologous recombination in the Dictyostelium alpha-actinin gene leads to an altered mRNA and lack of the protein.

1987 • 166 citations

Targeted transformation of Ascobolus immersus and de novo methylation of the resulting duplicated DNA sequences.

1989 • 158 citations

Locations and stability of Agrobacterium-mediated T-DNA insertions in the Lycopersicon genome

1986 • 137 citations

Targeted homologous recombination at the endogenous adenine phosphoribosyltransferase locus in Chinese hamster cells.

1989 • 98 citations

A molecular genetic analysis of insertions in the bronze locus in maize

1985 • 92 citations

The effect of site specific methylation on restriction endonuclease digestion

1985 • 84 citations

Recovery of Agrobacterium tumefaciens T-DNA molecules from whole plants early after transfer

1989 • 67 citations

Targeted Transformation of Ascobolus immersus and De Novo Methylation of the Resulting Duplicated DNA Sequences

1989 • 57 citations

Accurate modification of a chromosomal plasmid by homologous recombination in human cells.

1987 • 54 citations

Expression of tandem gene fusions in transgenic tobacco plants

1988 • 29 citations

Basic Processes Underlying Agrobacterium-Mediated DNA Transfer To Plant Cells

1988 • 18 citations

Genetic Engineering of Filamentous Fungi

1989 • 6 citations