Back to search

New semisynthetic pneumocandins with improved efficacies against Pneumocystis carinii in the rat

Data up to Jan 2025

Published1995
Citations44
References15

Total Citations Per Year

Abstract

References (15)

Pneumocandins from Zalerion arboricola. I. Discovery and isolation.

1992 • 122 citations

Synthesis and Antifungal Activity of Novel Cationic Pneumocandin Bo Derivatives

1994 • 109 citations

In vitro antifungal activities and in vivo efficacies of 1,3-beta-D-glucan synthesis inhibitors L-671,329, L-646,991, tetrahydroechinocandin B, and L-687,781, a papulacandin

1992 • 94 citations

Cilofungin (LY121019) inhibits Candida albicans (1-3)-beta-D-glucan synthase activity

1988 • 85 citations

Evaluation of water-soluble pneumocandin analogs L-733560, L-705589, and L-731373 with mouse models of disseminated aspergillosis, candidiasis, and cryptococcosis

1995 • 80 citations

Efficacy of cilofungin alone and in combination with amphotericin B in a murine model of disseminated aspergillosis

1991 • 75 citations

Synthesis, stability, and biological evaluation of water-soluble prodrugs of a new echinocandin lipopeptide. Discovery of a potential clinical agent for the treatment of systemic candidiasis and Pneumocystis carinii pneumonia (PCP)

1992 • 70 citations

Pneumocandins from Zalerion arboricola. IV. Biological evaluation of natural and semisynthetic pneumocandins for activity against Pneumocystis carinii and Candida species.

1992 • 58 citations

In vitro evaluation of the pneumocandin antifungal agent L-733560, a new water-soluble hybrid of L-705589 and L-731373

1995 • 52 citations

Use of beta-1,3-glucan-specific antibody to study the cyst wall of Pneumocystis carinii and effects of pneumocandin B0 analog L-733,560

1994 • 40 citations

Antipneumocystis activity of water-soluble lipopeptide L-693,989 in rats

1992 • 31 citations

Aerosolized L-693,989 for Pneumocystis carinii prophylaxis in rats

1994 • 15 citations

ChemInform Abstract: Chemical and Structure‐Activity Studies of the Echinocandin Lipopeptides

1993 • 13 citations

Comparative study of antipneumocystis agents in rats by using a Pneumocystis carinii-specific DNA probe to quantitate infection

1992 • 9 citations

Deleted Work

1955 • 0 citations

Cited By (0)

Loading...
New semisynthetic pneumocandins with improved efficacies against Pneumocystis carinii in… (1995) – Antimicrobial Agents and Chemotherapy | Metascience Observatory Explorer