GENETIC CONTROL OF DRUG LEVELS AND OF THE INDUCTION OF DRUG‐METABOLIZING ENZYMES IN MAN: INDIVIDUAL VARIABILITY IN THE EXTENT OF ALLOPURINOL AND NORTRIPTYLINE INHIBITION OF DRUG METABOLISM

Pharmacological implications of microsomal enzyme induction.

1967 • 2,883 citations

Species, strain and sex differences in metabolism of hexobarbitone, amidopyrine, antipyrine and aniline

1958 • 372 citations

Steady-state plasma levels of nortriptyline in twins: Influence of genetic factors and drug therapy

1969 • 361 citations

THE USE OF ANTIPYRINE IN THE MEASUREMENT OF TOTAL BODY WATER IN MAN

1949 • 346 citations

STUDIES ON THE ABSORPTION, DISTRIBUTION AND EXCRETION OF INDOMETHACIN IN VARIOUS SPECIES

1966 • 318 citations

The physiological disposition of phenylbutazone (butazolidin) in man and a method for its estimation in biological material.

1953 • 240 citations

Genetic Control of Drug Levels in Man: Antipyrine

1968 • 225 citations

Genetic control of the phenobarbital-induced shortening of plasma antipyrine half-lives in man

1969 • 224 citations

Cigarette Smoking: Stimulatory Effect on Metabolism of 3,4-Benzpyrene by Enzymes in Human Placenta

1968 • 194 citations

Determinants of the response to oral anticoagulant drugs in man.

1970 • 193 citations

Genetic Control of Drug Levels in Man: Phenylbutazone

1968 • 178 citations

Impairment of Drug Metabolism in Man by Allopurinol and Nortriptyline

1970 • 161 citations

Genetic control of dicumarol levels in man

1968 • 156 citations

Allopurinol: Alteration in Pyrimidine Metabolism in Man

1970 • 151 citations

Genetic basis of morphological variation: An evaluation and application of the twin study method.

1959 • 108 citations

The Treatment of Severe Myasthenia Gravis with Immunosuppressive Agents

1969 • 106 citations

The physiological disposition of dicumarol in man.

1950 • 105 citations

Dose-dependence of drug plasma level decline in dogs.

1967 • 98 citations

Methylphenidate Interaction With Both Anticonvulsants and Ethyl Biscoumacetate

1969 • 97 citations

Factors Altering the Responsiveness of Mice to Hexobarbital

1968 • 96 citations

A comparative study of the metabolism of desmethylimipramine, nortriptyline, and oxyphenylbutazone in man

1969 • 69 citations

Physicochemical and Biochemical Aspects of Pharmacology

1967 • 68 citations

Methylphenidate interaction with both anticonvulsants and ethyl biscoumacetate

1969 • 66 citations

The effect of caffeine on drug metabolism

1968 • 47 citations

THE INHIBITION OF TRYPTOPHAN PYRROLASE BY ALLOPURINOL, AN INHIBITOR OF XANTHINE OXIDASE

1967 • 47 citations

The effect of phenyramidol on the metabolism of bishydroxycoumarin.

1966 • 45 citations

Strain and age variations in hexobarbital response.

1967 • 41 citations

Stimulatory effect of nicotine on the metabolism of meprobamate

1966 • 34 citations

Time course differences in the metabolism of drugs by hepatic microsomes from rats, rabbits and mice.

1966 • 33 citations

Factors influencing the hexobarbital sleeping time and zoxazolamine paralysis time in mice

1968 • 32 citations

GUANETHIDINE AND RELATED AGENTS. II. METABOLISM BY HEPATIC MICROSOMES AND ITS INHIBITION BY DRUGS

1970 • 26 citations

Sex and Strain Differences in Basal and Induced Aniline Hydroxylase and Ethylmorphine N-Demethylase Activities from Domestic and Wild Rats

1969 • 24 citations

Application of Gas Chromatography to Toxicology

1963 • 10 citations

Strain differences in uptake, pool size and turnover rate of norepinephrine in hearts of mice

1970 • 5 citations