15 Design and Analysis of Cross-Over Trials

Generalized Linear Models

2005 • 21,170 citations

Longitudinal data analysis using generalized linear models

1986 • 17,084 citations

The Statistical Analysis of Failure Time Data.

1981 • 10,224 citations

Longitudinal Data Analysis for Discrete and Continuous Outcomes

1986 • 7,710 citations

Statistical Methods in Cancer Research

1980 • 6,825 citations

Nonparametric Statistical Methods

1999 • 6,387 citations

Models for Longitudinal Data: A Generalized Estimating Equation Approach

1988 • 4,384 citations

Small Sample Inference for Fixed Effects from Restricted Maximum Likelihood

1997 • 4,193 citations

An Approximate Distribution of Estimates of Variance Components

1946 • 4,173 citations

Note on the sampling error of the difference between correlated proportions or percentages

1947 • 3,814 citations

Maximum Likelihood Estimation of Misspecified Models

1983 • 3,727 citations

Recovery of inter-block information when block sizes are unequal

1971 • 3,597 citations

Nonparametric Statistical Methods.

1974 • 2,779 citations

Analysis of Binary Data

2008 • 2,760 citations

Residuals and Influence in Regression

1984 • 2,664 citations

Chi-Square Tests with One Degree of Freedom; Extensions of the Mantel-Haenszel Procedure

1963 • 2,648 citations

A comparison of the Two One-Sided Tests Procedure and the Power Approach for assessing the equivalence of average bioavailability

1987 • 2,396 citations

Clinical pharmacokinetics; concepts and applications

1989 • 2,266 citations

Meta-analyses involving cross-over trials: methodological issues

2002 • 2,169 citations

Fundamentals of Clinical Trials

2015 • 2,168 citations

Tests for Linear Trends in Proportions and Frequencies

1955 • 2,021 citations

Analysis of Categorical Data by Linear Models

1969 • 1,545 citations

Some Theorems on Quadratic Forms Applied in the Study of Analysis of Variance Problems, I. Effect of Inequality of Variance in the One-Way Classification

1954 • 1,494 citations

The two‐period cross‐over clinical trial.

1979 • 1,402 citations

Estimates of Location Based on Rank Tests

1963 • 1,168 citations

Experimental Designs Balanced for the Estimation of Residual Effects of Treatments

1949 • 1,056 citations

The Two-Period Change-Over Design and Its Use in Clinical Trials

1965 • 786 citations

Partial Proportional Odds Models for Ordinal Response Variables

1990 • 738 citations

Models for Discrete Longitudinal Data

2006 • 691 citations

Biased estimates of treatment effect in randomized experiments with nonlinear regressions and omitted covariates

1984 • 647 citations

A General Methodology for the Analysis of Experiments with Repeated Measurement of Categorical Data

1977 • 620 citations

Constructions and Combinatorial Problems in Design of Experiments

1973 • 599 citations

Some Theorems on Quadratic Forms Applied in the Study of Analysis of Variance Problems, II. Effects of Inequality of Variance and of Correlation Between Errors in the Two-Way Classification

1954 • 560 citations

A Comparison of Cluster-Specific and Population-Averaged Approaches for Analyzing Correlated Binary Data

1991 • 536 citations

Linear Mixed Models in Practice

1997 • 529 citations

Analysis of Longitudinal Data

2003 • 529 citations

Design and Analysis of Cross-Over Trials

2003 • 445 citations

Experimental Design: Theory and Application.

1956 • 441 citations

Misspecified proportional hazard models

1986 • 365 citations

A Method for Comparing Profiles of Repeated Measurements

1987 • 306 citations

Statistical Design and Analysis of Experiments

1999 • 302 citations

Classification and Analysis of Partially Balanced Incomplete Block Designs with Two Associate Classes

1952 • 286 citations

The performance of the two‐stage analysis of two‐treatment, two‐period crossover trials

1989 • 270 citations

Complete Counterbalancing of Immediate Sequential Effects in a Latin Square Design

1958 • 259 citations

Tables for An Approximate Test for Outliers in Linear Models

1975 • 239 citations

Repeated Measurements Designs, II

1978 • 181 citations

Balanced Repeated Measurements Designs

1980 • 178 citations

An exact test for comparing matched proportions in crossover designs

1969 • 177 citations

Bayesian Methods in Practice: Experiences in the Pharmaceutical Industry

1986 • 167 citations

A critique of recent research on the two-treatment crossover design

1989 • 162 citations

A Double Change-Over Design for Dairy Cattle Feeding Experiments

1941 • 145 citations

Power of the two one-sided tests procedure in bioequivalence

1990 • 143 citations

Elementary Medical Statistics

1965 • 142 citations

Semiparametric inference in a model for association in bivanate survival data

1986 • 139 citations

Cross-over Trials in Clinical Research

2003 • 122 citations

The Comparison of Success Rates in Cross-Over Trials in the Presence of an Order Effect

1981 • 118 citations

A small sample confidence interval approach to assess individual bioequivalence

2000 • 116 citations

Optimal Design and Refinement of the Linera Model with Applications to Repeated Measurements Designs

1983 • 115 citations

Analysis of Repeated Categorical Measurements with Conditional Likelihood Methods

1989 • 114 citations

Cyclic change-over designs

1969 • 113 citations

Extra-Period Latin-Square Change-Over Designs

1957 • 112 citations

A case study on the choice, interpretation and checking of multilevel models for longitudinal binary outcomes

2001 • 111 citations

Two-Treatment Crossover Designs for Estimating a Variety of Effects

1981 • 110 citations

Optimal crossover designs in the presence of carryover effects.

1983 • 108 citations

Optimality of Balanced Uniform Repeated Measurements Designs

1984 • 104 citations

Occupational stress among student nurses: A natural experiment.

1982 • 103 citations

Pharmacokinetics: Processes and Mathematics

1986 • 101 citations

A survey of models for repeated ordered categorical response data

1989 • 93 citations

A Two-Period Design with t 2 Experimental Units

1968 • 90 citations

Three-Period Crossover Designs for Two Treatments

1984 • 87 citations

A Bayesian Approach to Bioequivalence for the 2 x 2 Changeover Design

1981 • 85 citations

Quasi-Complete Latin Squares: Construction and Randomization

1984 • 84 citations

The analysis of data from 2 × 2 cross‐over trials with baseline measurements

1987 • 76 citations

Encyclopedia of Biopharmaceutical Statistics

2001 • 75 citations

THE CONSTRUCTION OF BALANCED DESIGNS FOR EXPERIMENTS INVOLVING SEQUENCES OF TREATMENTS

1952 • 73 citations

A Variational Approach to Optimal Two-Treatment Crossover Designs: Application to Carryover-Effect Models

1985 • 70 citations

Experimental Designs Balanced for Pairs of Residual Effect

1950 • 68 citations

3 Optimal crossover designs

1996 • 64 citations

Optimal crossover designs for the comparison of two treatments in the presence of carryover effects and autocorrelated errors

1987 • 62 citations

The analysis of matched proportions

1971 • 60 citations

Bayesian Approach to Bioequivalence Assessment: An Example

1983 • 58 citations

Recent Developments in Crossover Designs

1988 • 56 citations

Repeated measurements designs for a model with self and simple mixed carryover effects

2002 • 51 citations

Tests of significance in reversal or switchback trials

1938 • 51 citations

Optimal Two-Period Repeated Measurements Designs

1990 • 50 citations

Latin Squares to Balance Immediate Residual, and Other Order, Effects

1961 • 49 citations

Change-Over Designs with Complete Balance for First Residual Effects

1964 • 49 citations

Elementary Medical Statistics

1964 • 49 citations

Serially balanced sequences in bioassay

1956 • 47 citations

Use of baseline measurements in the two-period crossover design

1983 • 46 citations

Repeated measurements designs - a review

1990 • 46 citations

Change-Over Trials

1951 • 46 citations

The analysis of change-over trials

1950 • 45 citations

Optimal repeated measurements designs under interaction

1987 • 44 citations

Generalized cyclic designs in factorial experiments

1973 • 43 citations

Experimental designs in which each subject is used repeatedly.

1972 • 40 citations

Two-Factor Experiments in Non-Orthogonal Designs

1972 • 38 citations

Balanced repeated measurements designs

1983 • 37 citations

A Note on the Use of Nonparametric Methods in the Statistical Analysis of the Two-Period Changeover Design

1982 • 34 citations

ELEMENTARY MEDICAL STATISTICS: 2nd Edition

1964 • 34 citations

Cross-over designs in bioassay

1956 • 34 citations

Robust and realistic approaches to carry-over

1998 • 33 citations

Applications of Bayesian Software: Two Examples

1987 • 26 citations

Repeated Measurements Designs

1989 • 25 citations

199. Note: On the Analysis of Simple Cross-Overs with Unequal Numbers of Replicates

1964 • 22 citations

Serially Balanced Sequences

1955 • 21 citations

On Two Tests for Comparing Matched Proportions

1971 • 21 citations

Bioequivalence and Statistics in Clinical Pharmacology

2006 • 21 citations

Methods of Construction and Analysis of Serially Balanced Sequences

1957 • 21 citations

236. Note: The Analysis of Changeover Designs with Complete Balance for First Residual Effects

1967 • 20 citations

Quenouille's changeover designs

1973 • 19 citations

Some non‐parametric and categorical data analyses for a change‐over design study and discussion of apparent carry‐over effects

1983 • 18 citations

A Review of Higher Order Crossover Designs

1984 • 18 citations

Designs for sequences of treatments with carry-over effects.

1966 • 18 citations

The construction of nearly balanced and nearly strongly balanced uniform cross-over designs

2005 • 16 citations

The construction of good change-over designs when there are fewer units than treatments

1991 • 16 citations

CrossOver: an algorithm for the construction of efficient cross‐over designs

2004 • 16 citations

Some new row-complete Latin squares

1980 • 16 citations

SEQUENTIALLY BALANCED THREE-SQUARES CROSS-OVER DESIGNS

1996 • 15 citations

On Variance Estimation in Crossover Designs

1987 • 15 citations

Changeover Designs and Factorial Structure

1985 • 15 citations

Partially Balanced Change-Over Designs Based on M-Associate Class PBIB Designs

1980 • 14 citations

Some Remarks on the Analysis of Cross-Over Trials with a Binary Response

1985 • 14 citations

Changeover designs balanced for the linear component of first residual effects

1968 • 14 citations

An Example of the Use of Extended Cross-Over Designs in the Comparison of NPH Insulin Mixtures

1953 • 13 citations

Growth Curves in Two-Period Change Over Models

1981 • 13 citations

A new class of change-over designs for factorial experiments

1987 • 12 citations

A Change-Over Design for Testing a Treatment Factor at Four Equally Spaced Levels

1967 • 11 citations

Construction of sequentially counterbalanced designs formed from two Latin squares.

1999 • 9 citations

A 2×2 Factorial Design for Double Reversal Feeding Experiments

1944 • 9 citations

Using Bricks to Build Block Designs

1985 • 7 citations

The Gain in Efficiency Resulting from the Use of Balanced Designs

1938 • 6 citations

Deleted Work

1955 • 0 citations