Pre-B-cell colony-enhancing factor, whose expression is up-regulated in activated lymphocytes, is a nicotinamide phosphoribosyltransferase, a cytosolic enzyme involved in NAD biosynthesis

NITRIC OXIDE: A Physiologic Messenger Molecule

1994 • 2,299 citations

PSORT: a program for detecting sorting signals in proteins and predicting their subcellular localization

1999 • 2,159 citations

Poly(ADP-ribosyl)ation reactions in the regulation of nuclear functions

1999 • 1,753 citations

A quick and simple method for the quantitation of lactate dehydrogenase release in measurements of cellular cytotoxicity and tumor necrosis factor (TNF) activity

1988 • 1,288 citations

Nitric Oxide Activation of Poly(ADP-Ribose) Synthetase in Neurotoxicity

1994 • 1,138 citations

Cloning and characterization of the cDNA encoding a novel human pre-B-cell colony-enhancing factor.

1994 • 945 citations

A novel secretory pathway for interleukin-1 beta, a protein lacking a signal sequence.

1990 • 770 citations

The Plasticity of Dendritic Cell Responses to Pathogens and Their Components

2001 • 760 citations

Human macrophage activation programs induced by bacterial pathogens

2002 • 697 citations

Poly(ADP-ribosyl)ation reactions in the regulation of nuclear functions

1999 • 597 citations

Gene regulation mediated by calcium signals in T lymphocytes

2001 • 572 citations

Resistance to endotoxic shock as a consequence of defective NF-kappa B activation in poly (ADP-ribose) polymerase-1 deficient mice

1999 • 569 citations

A Derivative of NADP Mobilizes Calcium Stores Insensitive to Inositol Trisphosphate and Cyclic ADP-ribose

1995 • 479 citations

The Secretory Route of the Leaderless Protein Interleukin 1β Involves Exocytosis of Endolysosome-related Vesicles

1999 • 457 citations

Physiology and pathophysiology of poly(ADP‐ribosyl)ation *

2001 • 333 citations

Signatures of the Immune Response

2001 • 315 citations

Activation-induced cell death (apoptosis) of mature peripheral T lymphocytes

1993 • 314 citations

Regulation of calcium signalling in T lymphocytes by the second messenger cyclic ADP-ribose

1999 • 308 citations

New functions of a long‐known molecule

2000 • 289 citations

Cloning and Characterization of the cDNA Encoding a Novel Human pre-B-Cell Colony-enhancing Factor

1994 • 245 citations

Enzymology of Nad ⁺ Synthesis

1999 • 234 citations

Activation changes the spectrum but not the diversity of genes expressed by T cells

1999 • 227 citations

Widespread occurrence in animal tissues of an enzyme catalyzing the conversion of NAD+ into a cyclic metabolite with intracellular Ca2+-mobilizing activity

1989 • 191 citations

p38 MAPK signalling cascades: ancient roles and new functions

2000 • 190 citations

Nicotinic Acid Adenine Dinucleotide Phosphate (Naadp+) Is an Essential Regulator of T-Lymphocyte Ca2+-Signaling

2000 • 177 citations

Identification of a Plasmid-Encoded Gene from Haemophilus ducreyi Which Confers NAD Independence

2001 • 158 citations

Nitric Oxide: A Physiologic Messenger Molecule

1994 • 154 citations

A cellular survival switch: poly(ADP‐ribosyl)ation stimulates DNA repair and silences transcription

2001 • 122 citations

Glucocorticoids Attenuate T Cell Receptor Signaling

2001 • 119 citations

Nicotinamide Mononucleotide Pyrophosphorylase Activity in Animal Tissues

1966 • 107 citations

Multiple aspects of Rab protein action in the secretory pathway: Focus on Rab3 and Rab6

2000 • 93 citations

Augmentation in Expression of Activation-Induced Genes Differentiates Memory from Naive CD4+ T Cells and Is a Molecular Mechanism for Enhanced Cellular Response of Memory CD4+ T Cells

2001 • 68 citations

Global Expression Analysis of Extracellular Matrix–Integrin Interactions in Monocytes

2000 • 67 citations

Global analysis of neutrophil gene expression

2000 • 59 citations

Construction of Actinobacillus pleuropneumoniae-Escherichia coli shuttle vectors: expression of antibiotic-resistance genes

1995 • 41 citations

Antigen-Experienced T Cells Undergo a Transient Phase of Unresponsiveness Following Optimal Stimulation

1999 • 30 citations

A rapid procedure for assaying nicotinamide phosphoribosyltransferase

1980 • 24 citations

Induction of the pyridine nucleotide synthesis pathway in mitogen-stimulated human T-lymphocytes*1

1987 • 20 citations

Pyridine Nucleotide Synthesis

1972 • 20 citations

Evidence for a physiologically active nicotinamide phosphoribosyl transferase in cultured human fibroblasts

1982 • 19 citations

Mechanism of rat liver nicotinamide mononucleotide pyrophosphorylase

1969 • 17 citations

Nicotinamide Mononucleotide Determination of its Enzymatic Formation in vitro and its Physiological Rôle for the Biosynthesis of Nicotinamide‐Adenine Dinucleotide in Mice

1971 • 16 citations

Determination of nicotinamide phosphoribosyltransferase activity in human erythrocytes: High-performance liquid chromatography-linked method

1992 • 11 citations