Stromal cell derived factor-1: its influence on invasiveness and migration of breast cancer cells in vitro, and its association with prognosis and survival in human breast cancer

Global cancer statistics

2011 • 55,498 citations

Involvement of chemokine receptors in breast cancer metastasis

2001 • 5,203 citations

HIV-1 Entry Cofactor: Functional cDNA Cloning of a Seven-Transmembrane, G Protein-Coupled Receptor

1996 • 4,184 citations

The Role of Tumoral FOXP3 on Cell Proliferation, Migration, and Invasion in Gastric Cancer

2017 • 4,003 citations

Global cancer statistics

1999 • 3,388 citations

Function of the chemokine receptor CXCR4 in haematopoiesis and in cerebellar development

1998 • 2,496 citations

The Biology of Chemokines and their Receptors

2000 • 2,416 citations

The chemokine receptor CXCR4 is essential for vascularization of the gastrointestinal tract

1998 • 1,535 citations

Stromal Cell–Derived Factor-1 Effects on Ex Vivo Expanded Endothelial Progenitor Cell Recruitment for Ischemic Neovascularization

2003 • 1,147 citations

Molecular cloning and structure of a pre-B-cell growth-stimulating factor.

1994 • 818 citations

Signal Sequence Trap: a Cloning Strategy for Secreted Proteins and Type I Membrane Proteins

1993 • 722 citations

Structure and Chromosomal Localization of the Human Stromal Cell-Derived Factor 1 (SDF1) Gene

1995 • 629 citations

NF-κ B Promotes Breast Cancer Cell Migration and Metastasis by Inducing the Expression of the Chemokine Receptor CXCR4

2003 • 624 citations

Vascular Endothelial Growth Factor and Basic Fibroblast Growth Factor Induce Expression of CXCR4 on Human Endothelial Cells

1999 • 545 citations

Upregulation of CXCR4 is essential for HER2-mediated tumor metastasis

2004 • 519 citations

The Stromal Derived Factor–1/CXCL12–CXC Chemokine Receptor 4 Biological Axis in Non–Small Cell Lung Cancer Metastases

2003 • 455 citations

The chemokine receptor CXCR4 is required for outgrowth of colon carcinoma micrometastases.

2003 • 431 citations

Vascular endothelial growth factor promotes breast carcinoma invasion in an autocrine manner by regulating the chemokine receptor CXCR4.

2002 • 428 citations

Expression of stromal cell-derived factor 1 and CXCR4 ligand receptor system in pancreatic cancer: a possible role for tumor progression.

2000 • 422 citations

A Possible Role for CXCR4 and Its Ligand, the CXC Chemokine Stromal Cell-Derived Factor-1, in the Development of Bone Marrow Metastases in Neuroblastoma

2001 • 419 citations

Role of organ selectivity in the determination of metastatic patterns of B16 melanoma.

1980 • 417 citations

CXCR4–SDF-1 signaling is active in rhabdomyosarcoma cells and regulates locomotion, chemotaxis, and adhesion

2002 • 308 citations

Significance of Axillary Lymph Node Metastasis in Primary Breast Cancer

1999 • 292 citations

Stromal Cell-Derived Factor 1, a Novel Target of Estrogen Receptor Action, Mediates the Mitogenic Effects of Estradiol in Ovarian and Breast Cancer Cells

2003 • 290 citations

Regulation of CXCR4-mediated chemotaxis and chemoinvasion of breast cancer cells

2004 • 273 citations

CXCR4: chemokine receptor extraordinaire

2000 • 273 citations

Expression pattern of CXC chemokine receptor-4 is correlated with lymph node metastasis in human invasive ductal carcinoma

2003 • 261 citations

Recent trends in breast cancer incidence and mortality

2002 • 243 citations

A novel CXC chemokine PBSF/SDF-1 and its receptor CXCR4: their functions in development, hematopoiesis and HIV infection

1998 • 226 citations

Differential expression of the CCN family members Cyr61, CTGF and Nov in human breast cancer

2004 • 174 citations

Expression of peroxisome‐proliferator activated receptor‐gamma (PPARγ) and the PPARγ co‐activator, PGC‐1, in human breast cancer correlates with clinical outcomes

2003 • 164 citations

The role of chemoattraction in cancer metastases

2001 • 138 citations

Stromal Cell-Derived Factor-1α Promotes Melanoma Cell Invasion across Basement Membranes Involving Stimulation of Membrane-Type 1 Matrix Metalloproteinase and Rho GTPase Activities

2004 • 138 citations

Expression of Stromal-Derived Factor-1 Is Decreased by IL-1 and TNF and in Dermal Wound Healing

2001 • 136 citations

The elevated level of CXCR4 is correlated with nodal metastasis of human breast cancer

2005 • 129 citations

Selective secretion of chemoattractants for haemopoietic progenitor cells by bone marrow endothelial cells: a possible role in homing of haemopoietic progenitor cells to bone marrow

1999 • 123 citations

Activated leukocyte cell adhesion molecule in breast cancer: prognostic indicator

2004 • 119 citations

Regulation of the expression of E-cadherin on human cancer cells by gamma-linolenic acid (GLA).

1995 • 109 citations

Antagonistic effect of NK4, a novel hepatocyte growth factor variant, on in vitro angiogenesis of human vascular endothelial cells.

1999 • 94 citations

Stromal cells in lymph nodes attractB‐lymphoma cells via production ofstromal cell‐derived factor‐1

2000 • 75 citations

Genetic manipulation of stromal cell-derived factor-1 attests the pivotal role of the autocrine SDF-1-CXCR4 pathway in the aggressiveness of breast cancer cells

2005 • 66 citations

Production of Stromal Cell-Derived Factor-1 (SDF-1)and Expression of CXCR4 in Human Bone Marrow Endothelial Cells

2003 • 39 citations

Reduced Expression of Stromal-Derived Factor 1 in Autonomous Thyroid Adenomas and Its Regulation in Thyroid-Derived Cells¹

2001 • 36 citations

Prognostic Indicators in Early Breast Cancer

1993 • 26 citations