Back to search

Permanent Effects of Neonatal Estrogen Exposure in Rats on Reproductive Hormone Levels, Sertoli Cell Number, and the Efficiency of Spermatogenesis in Adulthood1

Data up to Jan 2025

Published1999
Citations254
References45

Total Citations Per Year

Abstract

References (45)

Are oestrogens involved in falling sperm counts and disorders of the male reproductive tract?

1993 • 1,887 citations

Generation and reproductive phenotypes of mice lacking estrogen receptor β

1998 • 1,680 citations

Male reproductive health and environmental xenoestrogens.

1996 • 1,383 citations

A role for oestrogens in the male reproductive system

1997 • 872 citations

Targeted disruption of the estrogen receptor gene in male mice causes alteration of spermatogenesis and infertility.

1996 • 827 citations

Proliferation of sertoli cells in fetal and postnatal rats: A quantitative autoradiographic study

1982 • 537 citations

Degeneration of germ cells in normal, hypophysectomized and hormone treated hypophysectomized rats

1977 • 445 citations

Serum inhibin B levels reflect Sertoli cell function in normal men and men with testicular dysfunction.

1996 • 387 citations

Male Reproductive Health and Environmental Xenoestrogens

1996 • 361 citations

Inhibin-B: a likely candidate for the physiologically important form of inhibin in men.

1996 • 317 citations

Inhibin B as a Serum Marker of Spermatogenesis: Correlation to Differences in Sperm Concentration and Follicle-Stimulating Hormone Levels. A Study of 349 Danish Men1

1997 • 301 citations

Expression of oestrogen receptor beta (ER beta) occurs in multiple cell types, including some germ cells, in the rat testis

1998 • 273 citations

In utero exposure to diethylstilbestrol: Adverse effects on the reproductive tract and reproductive performance in male and female offspring

1982 • 268 citations

Immunolocalisation of oestrogen receptor-α within the testis and excurrent ducts of the rat and marmoset monkey from perinatal life to adulthood

1997 • 263 citations

Adult testicular enlargement induced by neonatal hypothyroidism is accompanied by increased Sertoli and germ cell numbers.

1993 • 242 citations

Ontogeny of Estrogen Receptor-β Expression in Rat Testis**This work was supported by grants from the Swedish Medical Research Council (MFR K98–04P-12596–01A) and the Loo och Hans Ostermans Stiftelse (to G.G.J.M.K.) and a grant from the European Union (EU-PL95–1223; to B.v.d.B., P.T.v.d.S., and J.-Å.G.).

1999 • 227 citations

The Roles of Oestrogen in the Male

1998 • 221 citations

Inhibin B as a Serum Marker of Spermatogenesis: Correlation to Differences in Sperm Concentration and Follicle-Stimulating Hormone Levels. A Study of 349 Danish Men

1997 • 218 citations

Effect of neonatal exposure to estrogenic compounds on development of the excurrent ducts of the rat testis through puberty to adulthood.

1999 • 217 citations

A radioimmunoassay for testosterone in various biological fluids without chromatography

1978 • 200 citations

Inhibin A and inhibin B are inversely correlated to follicle-stimulating hormone, yet are discordant during the follicular phase of the rat estrous cycle, and inhibin A is expressed in a sexually dimorphic manner.

1996 • 189 citations

Abnormalities in Functional Development of the Sertoli Cells in Rats Treated Neonatally with Diethylstilbestrol: A Possible Role for Estrogens in Sertoli Cell Development1

1998 • 189 citations

Theory and practice of stereological techniques applied to the estimation of cell number and nuclear volume in the testis

1995 • 188 citations

Cell‐cell interactions in the control of spermatogenesis as studied using leydig cell destruction and testosterone replacement

1990 • 181 citations

Long-term Effects of Perinatal Exposure to Sex Steroids and Diethylstilbestrol on the Reproductive System of Male Mammals

1983 • 168 citations

Spontaneous degeneration of germ cells in normal rat testis: assessment of cell types and frequency during the spermatogenic cycle

1992 • 160 citations

Significance of Apoptosis in the Temporal and Stage-Specific Loss of Germ Cells in the Adult Rat after Gonadotropin Deprivation1

1997 • 152 citations

Expression of cytochrome P450 17alpha-hydroxylase/C17-20 lyase in the fetal rat testis is reduced by maternal exposure to exogenous estrogens.

1996 • 149 citations

Developmental hormonal profiles accompanying the neonatal hypothyroidism-induced increase in adult testicular size and sperm production in the rat.

1992 • 133 citations

Inhibin B Levels in Plasma of the Male Rat from Birth to Adulthood: Effect of Experimental Manipulation of Sertoli Cell Number

1999 • 131 citations

A matter of death and life: the significance of germ cell death during spermatogenesis

1998 • 117 citations

The Pre- and Postnatal Influence of Hormones and Neurotransmitters on Sexual Differentiation of the Mammalian Hypothalamus

1991 • 112 citations

Immunoexpression of Aquaporin-1 in the Efferent Ducts of the Rat and Marmoset Monkey during Development, Its Modulation by Estrogens, and Its Possible Role in Fluid Resorption*

1998 • 110 citations

Is FSH Required for Adult Spermatogenesis?

1994 • 100 citations

Inhibin B secretion in males with gonadotropin-releasing hormone (GnRH) deficiency before and during long-term GnRH replacement: relationship to spontaneous puberty, testicular volume, and prior treatment--a clinical research center study.

1996 • 95 citations

Estrogen Receptor in the Ductuli Efferentes, Epididymis, and Testis of Rhesus and Cynomolgus Macaques1

1990 • 85 citations

ALTERED SEXUAL DEVELOPMENT IN MALE RATS AFTER OESTROGEN ADMINISTRATION DURING THE NEONATAL PERIOD

1975 • 84 citations

The challenge posed by endocrine-disrupting chemicals.

1997 • 82 citations

Effects of Dietary 17β-Estradiol Exposure on Serum Hormone Concentrations and Testicular Parameters in Male Crl:CD BR Rats,

1998 • 80 citations

Determination of Sertoli cell numbers in the developing rat testis by stereological methods

1989 • 76 citations

Effects of Neonatal Administration of Diethylstilbestrol in Male Hamsters: Disruption of Reproductive Function in Adults after Apparently Normal Pubertal Development1

1998 • 61 citations

Neonatal exposure of male rats to estradiol benzoate causes rete testis dilation and backflow impairment of spermatogenesis

1998 • 52 citations

Cellular localisation of messenger RNAs in rat testis: application of digoxigenin-labelled ribonucleotide probes to embedded tissue

1993 • 51 citations

Developmental and Physiological Effects of Estrogen Receptor Gene Disruption in Mice

1997 • 45 citations

Possible role of changes in post-natal gonadotrophin concentrations on permanent impairment of the reproductive system in neonatally oestrogenized male rats

1990 • 26 citations

Cited By (0)

No citing papers found in database

Permanent Effects of Neonatal Estrogen Exposure in Rats on Reproductive Hormone Levels,… (1999) – Endocrinology | Metascience Observatory Explorer