Immunomodulation by various nitrosoureas and its effect on the survival of the murine host bearing a syngeneic tumor.

Cyclophosphamide-facilitated adoptive immunotherapy of an established tumor depends on elimination of tumor-induced suppressor T cells.

1982 • 640 citations

1,3-Bis(2-Chloroethyl)-1-Nitrosourea (Bcnu) And Other Nitrosoureas In Cancer Treatment: A Review

1973 • 167 citations

Cooperation between cyclophosphamide tumoricidal activity and host antitumor immunity in the cure of mice bearing large MOPC-315 tumors.

1981 • 100 citations

Importance of timing in cyclophosphamide therapy of MOPC-315 tumor-bearing mice.

1980 • 92 citations

Nitrosoureas: a review of experimental antitumor activity.

1976 • 91 citations

Chlorozotocin, 2-(3-(2-chloroethyl)-3-nitrosoureido)-D-glucopyranose, an antitumor agent with modified bone marrow toxicity.

1975 • 73 citations

Host-mediated therapeutic effects produced by appropriately timed administration of bleomycin on a rat fibrosarcoma.

1985 • 46 citations

Nitrosoureas in central nervous system tumors.

1973 • 43 citations

The role of suppressor T cells in BCNU-mediated rejection of a syngeneic tumor.

1985 • 37 citations

Normal Lyt-1+2- T cells have the unique capacity to respond to syngeneic autoreactive T cells. Demonstration of a T cell network.

1985 • 33 citations

Expression of the J11d marker on peripheral T lymphocytes of MRL-lpr/lpr mice.

1988 • 30 citations

Differential effects of BCNU on T cell, macrophage, natural killer and lymphokine-activated killer cell activities in mice bearing a syngeneic tumor

1988 • 23 citations

Chemotherapy of mice bearing syngeneic tumors with 1,3-bis (2-chloroethyl)-1-nitrosourea is effective only in normal, but not in irradiated or nude, mice: Role of L3T4+ (CD4+) and Lyt-2+ (CD8+) T cells

1988 • 15 citations

Ability of cyclophosphamide in the absence of cross-linking activity to exert the immunomodulatory effect required for the cure of mice bearing a large MOPC-315 tumor.

1986 • 14 citations

Host resistance to tumor after cure of advanced LSA lymphoma by treatment with BCNU and chlorozotocin.

1979 • 12 citations