Avirulence of rough mutants of Shigella flexneri: requirement of O antigen for correct unipolar localization of IcsA in the bacterial outer membrane

DNA sequencing with chain-terminating inhibitors

1977 • 69,181 citations

Experiments in molecular genetics

1972 • 28,260 citations

A comprehensive set of sequence analysis programs for the VAX

1984 • 14,824 citations

“Western Blotting”: Electrophoretic transfer of proteins from sodium dodecyl sulfate-polyacrylamide gels to unmodified nitrocellulose and radiographic detection with antibody and radioiodinated protein A

1981 • 8,657 citations

A sensitive silver stain for detecting lipopolysaccharides in polyacrylamide gels

1982 • 3,066 citations

Experiments With Gene Fusions

1984 • 2,487 citations

Morphological heterogeneity among Salmonella lipopolysaccharide chemotypes in silver-stained polyacrylamide gels

1983 • 1,971 citations

Involvement of a plasmid in the invasive ability of Shigella flexneri

1982 • 733 citations

Identification of icsA, a plasmid locus of Shigella flexneri that governs bacterial intra- and intercellular spread through interaction with F-actin.

1989 • 724 citations

EPITHELIAL CELL PENETRATION AS AN ESSENTIAL STEP IN THE PATHOGENESIS OF BACILLARY DYSENTERY

1964 • 628 citations

Structure and sequence of the rfb (O antigen) gene cluster of Salmonella serovar typhimurium (strain LT2)

1991 • 346 citations

Entry of Shigella flexneri into HeLa cells: evidence for directed phagocytosis involving actin polymerization and myosin accumulation

1987 • 327 citations

A genetic determinant required for continuous reinfection of adjacent cells on large plasmid in S. flexneri 2a

1986 • 312 citations

Cloning of plasmid DNA sequences involved in invasion of HeLa cells by Shigella flexneri

1985 • 306 citations

Intracellular and cell-to-cell spread of Listeria monocytogenes involves interaction with F-actin in the enterocytelike cell line Caco-2

1990 • 301 citations

Alterations in the pathogenicity of Escherichia coli K-12 after transfer of plasmid and chromosomal genes from Shigella flexneri

1983 • 299 citations

Unipolar localization and ATPase activity of IcsA, a Shigella flexneri protein involved in intracellular movement

1993 • 293 citations

Genetic basis of virulence in Shigella species

1991 • 293 citations

Experimental keratoconjunctivitis shigellosa.

1957 • 263 citations

Plaque formation by virulent Shigella flexneri

1985 • 253 citations

Alterations in the Outer Membrane of the Cell Envelope of Heptose-Deficient Mutants of Escherichia coli

1974 • 242 citations

virG, a plasmid-coded virulence gene of Shigella flexneri: identification of the virG protein and determination of the complete coding sequence

1989 • 240 citations

icsB: a Shigella flexneri virulence gene necessary for the lysis of protrusions during intercellular spread

1992 • 178 citations

Evidence that glutamic acid 167 is an active-site residue of Shiga-like toxin I.

1988 • 153 citations

Biosynthesis of enterobacterial common antigen in Escherichia coli. Biochemical characterization of Tn10 insertion mutants defective in enterobacterial common antigen synthesis.

1990 • 136 citations

The Lipopolysaccharide of Shigella Bacteria as a Virulence Factor

1991 • 115 citations

Function of the rfb gene cluster and the rfe gene in the synthesis of O antigen by Shigella dysenteriae 1

1993 • 114 citations

Structure and biology of Shigella flexneri O antigens

1987 • 112 citations

UTP: alpha-D-glucose-1-phosphate uridylyltransferase of Escherichia coli: isolation and DNA sequence of the galU gene and purification of the enzyme

1994 • 103 citations

Lipopolysaccharide structure required for in vitro trimerization of Escherichia coli OmpF porin

1991 • 99 citations

Temperature regulation of Shigella virulence: identification of the repressor gene virR, an analogue of hns, and partial complementation by tyrosyl transfer RNA (tRNA₁^Tyr)

1992 • 98 citations

Involvement of lipopolysaccharide in the secretion of Escherichia coli α haemolysin and Erwinia chrysanthemi proteases

1993 • 86 citations

Bacillus subtilis gtaB encodes UDP-glucose pyrophosphorylase and is controlled by stationary-phase transcription factor sigma B

1993 • 83 citations

In vitro trimerization of OmpF porin secreted by spheroplasts of Escherichia coli.

1990 • 80 citations

Virulence‐associated chromosomal loci of Shigella flexneri identified by random Tn5 insertion mutagenesis

1991 • 79 citations

A small plasmid in Shigella dysenteriae 1 specifies one or more functions essential for O antigen production and bacterial virulence

1984 • 76 citations

Role of the rfe gene in the synthesis of the O8 antigen in Escherichia coli K-12

1994 • 75 citations

Effects of galU mutation on flagellar formation in Escherichia coli

1977 • 68 citations

HeLa cell invasiveness and O antigen of Shigella flexneri as separate and prerequisite attributes of virulence to evoke keratoconjunctivitis in guinea pigs

1983 • 68 citations

Identification of Shigella invasion genes by isolation of temperature-regulated inv::lacZ operon fusions

1989 • 65 citations

Nucleotide sequence of the rhamnose biosynthetic operon of Shigella flexneri 2a and role of lipopolysaccharide in virulence

1994 • 63 citations

Polarized cells, polar actions

1993 • 57 citations

Multicopy suppression: an approach to understanding intracellular functioning of the protein export system

1992 • 56 citations

Assembly of an in vitro synthesized Escherichia coli outer membrane porin into its stable trimeric configuration.

1990 • 54 citations

[38] UDP-glucose pyrophosphorylase (crystalline) from liver

1966 • 45 citations

Rough mutant of Shigella flexneri 2a that penetrates tissue culture cells but does not evoke keratoconjunctivitis in guinea pigs

1977 • 39 citations

Nucleotide sequence and expression analysis of the Acetobacter xylinum uridine diphosphoglucose pyrophosphorylase gene

1991 • 36 citations

Chromosomal location of the gene determining uridine diphoglucose formation in Escherichia coli K-12.

1966 • 30 citations