Mapping antigenic sites on the major outer membrane protein of Chlamydia trachomatis with synthetic peptides

A simple method for displaying the hydropathic character of a protein

1982 • 22,471 citations

Prediction of protein antigenic determinants from amino acid sequences.

1981 • 3,715 citations

Use of peptide synthesis to probe viral antigens for epitopes to a resolution of a single amino acid.

1984 • 1,467 citations

Synthetic peptide vaccine design: synthesis and properties of a high-density multiple antigenic peptide system.

1988 • 1,241 citations

Three-Dimensional Structure of an Antigen-Antibody Complex at 2.8 Å Resolution

1986 • 1,173 citations

Strategies for epitope analysis using peptide synthesis

1987 • 887 citations

Correlation between segmental mobility and the location of antigenic determinants in proteins

1984 • 590 citations

Immunologic Relationship Between Genital Tric, Lymphogranuloma Venereum, and Related Organisms in a New Microtiter Indirect Immunofluorescence Test

1970 • 551 citations

A synthetic vaccine protects humans against challenge with asexual blood stages of Plasmodium falciparum malaria

1988 • 413 citations

Improved immunogenicity of a peptide epitope after fusion to hepatitis B core protein

1987 • 335 citations

Mapping antigenic domains expressed by Chlamydia trachomatis major outer membrane protein genes.

1988 • 323 citations

Location of ‘continuous’ antigenic determinants in the protruding regions of proteins.

1986 • 285 citations

Diversity of Chlamydia trachomatis major outer membrane protein genes

1987 • 275 citations

Nucleotide and deduced amino acid sequences for the four variable domains of the major outer membrane proteins of the 15 Chlamydia trachomatis serovars

1989 • 269 citations

Monoclonal antibodies to Chlamydia trachomatis: antibody specificities and antigen characterization.

1982 • 258 citations

Protective monoclonal antibodies recognize epitopes located on the major outer membrane protein of Chlamydia trachomatis.

1987 • 253 citations

Chemistry of Antibody Binding to a Protein

1987 • 251 citations

High-resolution mapping of serovar-specific and common antigenic determinants of the major outer membrane protein of Chlamydia trachomatis.

1988 • 172 citations

Antigen-antibody interaction. Synthetic peptides define linear antigenic determinants recognized by monoclonal antibodies directed to the cytoplasmic carboxyl terminus of rhodopsin.

1988 • 149 citations

Stimulation of choleragen enzymatic activities by GTP and two soluble proteins purified from bovine brain.

1988 • 141 citations

Trachoma Vaccine Studies in Monkeys

1967 • 132 citations

In vitro neutralization of Chlamydia trachomatis with monoclonal antibody to an epitope on the major outer membrane protein

1984 • 125 citations

Synthetic peptides: a next generation of vaccines?

1987 • 100 citations

Epitope Mapping of Foot-and-Mouth Disease Virus with Neutralizing Monoclonal Antibodies

1989 • 98 citations

A Critical Evaluation of Methods for Prediction of Protein Secondary Structures

1988 • 94 citations

Protective role of magnesium in the neutralization by antibodies of Chlamydia trachomatis infectivity

1988 • 75 citations

Epitope mapping with solid‐phase peptides: identification of type‐, subspecies‐, species‐ and genus‐reactive antibody binding domains on the major outer membrane protein of Chlamydia trachomatis

1988 • 74 citations

Neutralization of Chlamydia trachomatis cell culture infection by serovar-specific monoclonal antibodies

1985 • 69 citations

Field Studies of Protection from Infection by Experimental Trachoma Virus Vaccine in Preschool-Aged Children on Taiwan.

1963 • 61 citations

Molecular cloning and expression of Chlamydia trachomatis major outer membrane protein antigens in Escherichia coli

1985 • 48 citations

Use of synthetic peptides to map the antigenic determinants of glycoprotein D of herpes simplex virus

1988 • 47 citations

Computer prediction of potential immunogenic determinants from protein amino acid sequence

1987 • 45 citations

Antigenic structure of sperm whale myoglobin. I. Partition of specificities between antibodies reactive with peptides and native protein.

1982 • 39 citations

Antigenic analysis of the major outer membrane protein of Chlamydia trachomatis with murine monoclonal antibodies

1986 • 38 citations

Antigenic structure of sperm whale myoglobin. II. Characterization of antibodies preferentially reactive with peptides arising in response to immunization with the native protein.

1982 • 34 citations

Static accessibility model of protein antigenicity: the case of scorpion neurotoxin

1986 • 29 citations

The major outer membrane protein of Chlamydia trachomatis: critical binding site and conformation determine the specificity of antibody binding to viable chlamydiae

1989 • 14 citations

Identification of conserved regions for species and subspecies specific epitopes on the major outer membrane protein of Chlamydia trachomatis

1987 • 6 citations