Acute graft versus host disease

Two types of murine helper T cell clone. I. Definition according to profiles of lymphokine activities and secreted proteins.

1986 • 7,504 citations

1994 Consensus Conference on Acute GVHD Grading.

1995 • 4,743 citations

Bone Marrow Transplant

2001 • 3,479 citations

Nonmyeloablative Stem Cell Transplantation and Cell Therapy as an Alternative to Conventional Bone Marrow Transplantation With Lethal Cytoreduction for the Treatment of Malignant and Nonmalignant Hematologic Diseases

1998 • 1,984 citations

Nonmyeloablative Stem Cell Transplantation and Cell Therapy as an Alternative to Conventional Bone Marrow Transplantation With Lethal Cytoreduction for the Treatment of Malignant and Nonmalignant Hematologic Diseases

1998 • 1,765 citations

Methotrexate and Cyclosporine Compared with Cyclosporine Alone for Prophylaxis of Acute Graft versus Host Disease after Marrow Transplantation for Leukemia

1986 • 1,453 citations

Mesenchymal Stem Cells for Treatment of Therapy-Resistant Graft-versus-Host Disease

2006 • 1,126 citations

Analysis of 462 Transplantations from Unrelated Donors Facilitated by the National Marrow Donor Program

1993 • 873 citations

Marrow Transplantation from Related Donors Other Than HLA-Identical Siblings

1985 • 844 citations

The primacy of the gastrointestinal tract as a target organ of acute graft-versus-host disease: rationale for the use of cytokine shields in allogeneic bone marrow transplantation

2000 • 702 citations

Impact of HLA class I and class II high-resolution matching on outcomes of unrelated donor bone marrow transplantation: HLA-C mismatching is associated with a strong adverse effect on transplantation outcome

2004 • 694 citations

Stable Mixed Hematopoietic Chimerism in DLA-Identical Littermate Dogs Given Sublethal Total Body Irradiation Before and Pharmacological Immunosuppression After Marrow Transplantation

1997 • 633 citations

Phase 3 study comparing methotrexate and tacrolimus with methotrexate and cyclosporine for prophylaxis of acute graft-versus-host disease after marrow transplantation from unrelated donors.

2000 • 574 citations

Summary of the Guidelines for Preventing Opportunistic Infections among Hematopoietic Stem Cell Transplant Recipients

2001 • 569 citations

Allogeneic marrow transplantation in patients with acute myeloid leukemia in first remission: a randomized trial of two irradiation regimens [see comments]

1990 • 525 citations

Results of allogeneic bone marrow transplants for leukemia using donors other than HLA-identical siblings.

1997 • 484 citations

Allogeneic marrow transplantation in patients with acute myeloid leukemia in first remission: a randomized trial of two irradiation regimens [see comments]

1990 • 446 citations

Acute and Chronic Graft-Versus-Host Disease After Allogeneic Peripheral-Blood Stem-Cell and Bone Marrow Transplantation: A Meta-Analysis

2001 • 430 citations

Comparison of chronic graft-versus-host disease after transplantation of peripheral blood stem cells versus bone marrow in allogeneic recipients: long-term follow-up of a randomized trial

2002 • 414 citations

How I treat refractory acute GVHD

2007 • 400 citations

Response of 443 patients to steroids as primary therapy for acute graft-versus-host disease: Comparison of grading systems

2002 • 391 citations

Pathophysiologic mechanisms of acute graft-vs.-host disease

1999 • 348 citations

RISK FACTORS FOR ACUTE GRAFT-VERSUS-HOST DISEASE IN HISTOCOMPATIBLE DONOR BONE MARROW TRANSPLANTATION

1991 • 271 citations

Successful Allogeneic Transplantation of T-Cell–Depleted Bone Marrow from Closely HLA-Matched Unrelated Donors

1990 • 267 citations

Allogeneic Marrow Stem-Cell Transplantation From Human Leukocyte Antigen–Identical Siblings Versus Human Leukocyte Antigen–Allelic–Matched Unrelated Donors (10/10) in Patients With Standard-Risk Hematologic Malignancy: A Prospective Study From the French Society of Bone Marrow Transplantation and Cell Therapy

2006 • 265 citations

Tumor necrosis factor-α blockade for the treatment of acute GVHD

2004 • 260 citations

Nonmyeloablative transplantation with or without alemtuzumab: comparison between 2 prospective studies in patients with lymphoproliferative disorders

2002 • 253 citations

How I treat chronic graft-versus-host disease

2001 • 252 citations

Gastrointestinal graft-versus-host disease in man

1979 • 251 citations

Risk Factors for Acute Graft-Versus-Host Disease After Allogeneic Blood Stem Cell Transplantation

1999 • 231 citations

The Pathophysiology of Acute Graft-versus-Host Disease

2003 • 231 citations

Early treatment of acute graft-versus-host disease with high- or low-dose 6-methylprednisolone : a multicenter randomized trial from the Italian Group for Bone Marrow Transplantation

1998 • 220 citations

The effect of intensified extracorporeal photochemotherapy on long-term survival in patients with severe acute graft-versus-host disease.

2006 • 213 citations

Acute and chronic graft-versus-host disease after ablative and nonmyeloablative conditioning for allogeneic hematopoietic transplantation

2004 • 211 citations

Prospective evaluation of 2 acute graft-versus-host (GVHD) grading systems: a joint Societe Francaise de Greffe de Moelle et Therapie Cellulaire (SFGM-TC), Dana Farber Cancer Institute (DFCI), and International Bone Marrow Transplant Registry (IBMTR) prospective study

2005 • 204 citations

Infliximab use in patients with severe graft-versus-host disease and other emerging risk factors of non-Candida invasive fungal infections in allogeneic hematopoietic stem cell transplant recipients: a cohort study

2003 • 187 citations

Differential use of Fas ligand and perforin cytotoxic pathways by donor T cells in graft-versus-host disease and graft-versus-leukemia effect

2001 • 187 citations

SIROLIMUS (RAPAMYCIN) FOR THE TREATMENT OF STEROID-REFRACTORY ACUTE GRAFT-VERSUS-HOST DISEASE1

2001 • 186 citations

Selective depletion of CD8+ T lymphocytes for prevention of graft- versus-host disease after allogeneic bone marrow transplantation

1990 • 180 citations

Selective depletion of CD8+ T lymphocytes for prevention of graft- versus-host disease after allogeneic bone marrow transplantation

1990 • 166 citations

Poor outcome in steroid-refractory graft-versus-host disease with antithymocyte globulin treatment

2002 • 154 citations

Increasingly frequent diagnosis of acute gastrointestinal graft-versus-host disease after allogeneic hematopoietic cell transplantation

2004 • 152 citations

Effect of HLA class II gene disparity on clinical outcome in unrelated donor hematopoietic cell transplantation for chronic myeloid leukemia: the US National Marrow Donor Program Experience

2001 • 151 citations

Cyclosporine v methotrexate for graft-v-host disease prevention in patients given marrow grafts for leukemia: long-term follow-up of three controlled trials

1988 • 142 citations

Pillars Article: Two Types of Murine Helper T Cell Clone. I. Definition According to Profiles of Lymphokine Activities and Secreted Proteins. J. Immunol., 1986, 136: 2348–2357.

2005 • 142 citations

Donor T cell–derived TNF is required for graft-versus-host disease and graft-versus-tumor activity after bone marrow transplantation

2003 • 132 citations

Pentostatin in Steroid-Refractory Acute Graft-Versus-Host Disease

2005 • 121 citations

Acute lung injury after allogeneic stem cell transplantation: is the lung a target of acute graft-versus-host disease?

2004 • 114 citations

Hepatitic variant of graft-versus-host disease after donor lymphocyte infusion

2002 • 112 citations

A survey of the prophylaxis and treatment of acute GVHD in Europe: a report of the European Group for Blood and Marrow Transplantation (EBMT)

1997 • 111 citations

Prognostic value of apoptotic cells and infiltrating neutrophils in graft-versus-host disease of the gastrointestinal tract in humans: TNF and Fas expression

2003 • 101 citations

Hyperacute GVHD: risk factors, outcomes, and clinical implications

2006 • 100 citations

Previous donor pregnancy as a risk factor for acute graft‐versus‐host disease in patients with aplastic anaemia treated by allogeneic marrow transplantation

1990 • 99 citations

Influence of T-cell depletion on chronic graft-versus-host disease: results of a multicenter randomized trial in unrelated marrow donor transplantation

2005 • 98 citations

PREDNISONE THERAPY FOR ACUTE GRAFT-VERSUS-HOST DISEASE

1993 • 87 citations

Risk assessment in haematopoietic stem cell transplantation: Histocompatibility

2007 • 75 citations

A novel reduced intensity regimen for allogeneic hematopoietic stem cell transplantation associated with a reduced incidence of graft-versus-host disease

2004 • 66 citations

HIGH-DOSE METHYLPREDNISOLONE TREATMENT FOR ACUTE GRAFT-VERSUS-HOST DISEASE AFTER BONE MARROW TRANSPLANTATION IN ADULTS

1984 • 58 citations

High dose bolus methylprednisolone for the treatment of acute graft versus host disease

1983 • 54 citations

Clinical “cytokine storm” as revealed by monocyte intracellular flow cytometry: correlation of tumor necrosis factor α with severe gut graft-versus-host disease

2004 • 43 citations

Review article: management of hepatic disease following haematopoietic cell transplant

2006 • 43 citations

Accumulation and Activation-Induced Release of Preformed Fas (CD95) Ligand During the Pathogenesis of Experimental Graft-Versus-Host Disease

2001 • 41 citations

Outcomes of unrelated cord blood transplants and allogeneic-related hematopoietic stem cell transplants in children with high-risk acute lymphocytic leukemia

2004 • 41 citations

Nonmyeloablative Hematopoietic Stem Cell Transplant for X-Linked Hyper-Immunoglobulin M Syndrome With Cholangiopathy

2004 • 41 citations

Surveillance of cytomegalovirus infection in haematopoietic stem cell transplantation patients

2003 • 32 citations

Hepatitic pattern of graft versus host disease in children

2006 • 26 citations

Skin biopsy in allogeneic and autologous bone marrow transplant patients: a histologic and immunohistochemical study and review of the literature.

1995 • 24 citations

Immunogenomics of unrelated hematopoietic cell transplantation

2006 • 21 citations

Graft failure and graft-vs-host disease after subtotal T-cell-depleted marrow transplantation: correlations with marrow hematopoietic and lymphoid subsets.

1994 • 10 citations