Avian influenza A (H5N1)

Evolution and ecology of influenza A viruses

1992 • 4,023 citations

Evolution and ecology of influenza A viruses.

1992 • 2,193 citations

Strategies for containing an emerging influenza pandemic in Southeast Asia

2005 • 1,851 citations

Characterization of a Novel Influenza A Virus Hemagglutinin Subtype (H16) Obtained from Black-Headed Gulls

2005 • 1,559 citations

Human influenza A H5N1 virus related to a highly pathogenic avian influenza virus

1998 • 1,386 citations

Characterization of an Avian Influenza A (H5N1) Virus Isolated from a Child with a Fatal Respiratory Illness

1998 • 1,351 citations

Genesis of a highly pathogenic and potentially pandemic H5N1 influenza virus in eastern Asia

2004 • 1,337 citations

Containing Pandemic Influenza at the Source

2005 • 1,199 citations

Avian influenza A virus (H7N7) associated with human conjunctivitis and a fatal case of acute respiratory distress syndrome

2004 • 1,080 citations

Clinical features and rapid viral diagnosis of human disease associated with avian influenza A H5N1 virus

1998 • 1,047 citations

Molecular Basis for the Generation in Pigs of Influenza A Viruses with Pandemic Potential

1998 • 1,007 citations

Receptor determinants of human and animal influenza virus isolates: Differences in receptor specificity of the H3 hemagglutinin based on species of origin

1983 • 908 citations

Induction of proinflammatory cytokines in human macrophages by influenza A (H5N1) viruses: a mechanism for the unusual severity of human disease?

2002 • 893 citations

Probable Person-to-Person Transmission of Avian Influenza A (H5N1)

2005 • 875 citations

Avian Influenza A (H5N1) in 10 Patients in Vietnam

2004 • 841 citations

Transmission of H7N7 avian influenza A virus to human beings during a large outbreak in commercial poultry farms in the Netherlands

2004 • 822 citations

Re-emergence of fatal human influenza A subtype H5N1 disease

2004 • 816 citations

Transmissibility of 1918 pandemic influenza

2004 • 804 citations

H5N1 virus outbreak in migratory waterfowl

2005 • 802 citations

Detection of Antibody to Avian Influenza A (H5N1) Virus in Human Serum by Using a Combination of Serologic Assays

1999 • 800 citations

Avian-to-human transmission of the PB1 gene of influenza A viruses in the 1957 and 1968 pandemics

1989 • 791 citations

Receptor Specificity in Human, Avian, and Equine H2 and H3 Influenza Virus Isolates

1994 • 784 citations

Human and avian influenza viruses target different cell types in cultures of human airway epithelium

2004 • 765 citations

Genetic Characterization of the Pathogenic Influenza A/Goose/Guangdong/1/96 (H5N1) Virus: Similarity of Its Hemagglutinin Gene to Those of H5N1 Viruses from the 1997 Outbreaks in Hong Kong

1999 • 727 citations

The Structure and Receptor Binding Properties of the 1918 Influenza Hemagglutinin

2004 • 713 citations

Molecular characterization of H9N2 influenza viruses: Were they the donors of the “internal” genes of H5N1 viruses in Hong Kong?

1999 • 711 citations

Initial Genetic Characterization of the 1918 “Spanish” Influenza Virus

1997 • 706 citations

Single amino acid substitutions in influenza haemagglutinin change receptor binding specificity

1983 • 676 citations

On the origin of the human influenza virus subtypes H2N2 and H3N2

1978 • 675 citations

Are We Ready for Pandemic Influenza?

2003 • 662 citations

The Surface Glycoproteins of H5 Influenza Viruses Isolated from Humans, Chickens, and Wild Aquatic Birds Have Distinguishable Properties

1999 • 607 citations

Origin and evolution of the 1918 “Spanish” influenza virus hemagglutinin gene

1999 • 600 citations

The evolution of H5N1 influenza viruses in ducks in southern China

2004 • 528 citations

Fatal Avian Influenza A (H5N1) in a Child Presenting with Diarrhea Followed by Coma

2005 • 518 citations

Role of domestic ducks in the propagation and biological evolution of highly pathogenic H5N1 influenza viruses in Asia

2005 • 505 citations

Encephalitis and Encephalopathy Associated with an Influenza Epidemic in Japan

2002 • 495 citations

Avian Influenza H5N1 in Tigers and Leopards

2004 • 487 citations

Structure of the Uncleaved Human H1 Hemagglutinin from the Extinct 1918 Influenza Virus

2004 • 477 citations

Outbreak of Avian Influenza A(H5N1) Virus Infection in Hong Kong in 1997

2002 • 476 citations

Enhanced virulence of influenza A viruses with the haemagglutinin of the 1918 pandemic virus

2004 • 457 citations

Avian H5N1 Influenza in Cats

2004 • 445 citations

Influenza virus strains selectively recognize sialyloligosaccharides on human respiratory epithelium; the role of the host cell in selection of hemagglutinin receptor specificity

1993 • 441 citations

Pathology of fatal human infection associated with avian influenza A H5N1 virus

2001 • 432 citations

Reemerging H5N1 Influenza Viruses in Hong Kong in 2002 Are Highly Pathogenic to Ducks

2004 • 410 citations

Avian Influenza A Viruses Differ from Human Viruses by Recognition of Sialyloligosaccharides and Gangliosides and by a Higher Conservation of the HA Receptor-Binding Site

1997 • 400 citations

H5N1 influenza: A protean pandemic threat

2004 • 396 citations

Human Disease from Influenza A (H5N1), Thailand, 2004

2005 • 379 citations

Potential for transmission of avian influenza viruses to pigs

1994 • 377 citations

Human Illness from Avian Influenza H7N3, British Columbia

2004 • 376 citations

Emergence of multiple genotypes of H5N1 avian influenza viruses in Hong Kong SAR

2002 • 374 citations

Cellular transcriptional profiling in influenza A virus-infected lung epithelial cells: The role of the nonstructural NS1 protein in the evasion of the host innate defense and its potential contribution to pandemic influenza

2002 • 370 citations

Safety and immunogenicity of a recombinant hemagglutinin vaccine for H5 influenza in humans

2001 • 326 citations

Replication of avian influenza viruses in humans

1991 • 319 citations

Receptor binding properties of human and animal H1 influenza virus isolates

1989 • 305 citations

Case‐Control Study of Risk Factors for Avian Influenza A (H5N1) Disease, Hong Kong, 1997

1999 • 289 citations

Risk of Influenza A (H5N1) Infection among Poultry Workers, Hong Kong, 1997–1998

2002 • 285 citations

Cross‐Reactivity to Highly Pathogenic Avian Influenza H5N1 Viruses after Vaccination with Nonadjuvanted and MF59‐Adjuvanted Influenza A/Duck/Singapore/97 (H5N3) Vaccine: A Potential Priming Strategy

2005 • 282 citations

Sequence of the 1918 pandemic influenza virus nonstructural gene (NS) segment and characterization of recombinant viruses bearing the 1918 NS genes

2001 • 278 citations

Influenza A H5N1 Replication Sites in Humans

2005 • 265 citations

Specification of Receptor-Binding Phenotypes of Influenza Virus Isolates from Different Hosts Using Synthetic Sialylglycopolymers: Non-Egg-Adapted Human H1 and H3 Influenza A and Influenza B Viruses Share a Common High Binding Affinity for 6′-Sialyl(N-acetyllactosamine)

1997 • 255 citations

Comparison of Efficacies of RWJ-270201, Zanamivir, and Oseltamivir against H5N1, H9N2, and Other Avian Influenza Viruses

2001 • 244 citations

Characterization of Highly Pathogenic H5N1 Avian Influenza A Viruses Isolated from South Korea

2005 • 243 citations

Antibody Response in Individuals Infected with Avian Influenza A (H5N1) Viruses and Detection of Anti‐H5 Antibody among Household and Social Contacts

1999 • 243 citations

Responsiveness to a pandemic alert: use of reverse genetics for rapid development of influenza vaccines

2004 • 240 citations

Evolution of the H3 influenza virus hemagglutinin from human and nonhuman hosts

1992 • 227 citations

Molecular characterization of the complete genome of human influenza H5N1 virus isolates from Thailand

2005 • 218 citations

Influenza A pandemics of the 20th century with special reference to 1918: virology, pathology and epidemiology

2000 • 212 citations

Replication of avian influenza A viruses in mammals

1981 • 207 citations

Characterization of H5N1 Influenza Viruses That Continue To Circulate in Geese in Southeastern China

2002 • 204 citations

Evidence of an absence: the genetic origins of the 1918 pandemic influenza virus

2004 • 200 citations

Studies of H5N1 Influenza Virus Infection of Pigs by Using Viruses Isolated in Vietnam and Thailand in 2004

2005 • 200 citations

Virus-neutralizing antibodies of immunoglobulin G (IgG) but not of IgM or IgA isotypes can cure influenza virus pneumonia in SCID mice

1995 • 200 citations

Virulence May Determine the Necessary Duration and Dosage of Oseltamivir Treatment for Highly Pathogenic A/Vietnam/1203/04 Influenza Virus in Mice

2005 • 173 citations

Confronting the avian influenza threat: vaccine development for a potential pandemic

2004 • 173 citations

The neuraminidase inhibitor GS4104 (oseltamivir phosphate) is efficacious against A/Hong Kong/156/97 (H5N1) and A/Hong Kong/1074/99 (H9N2) influenza viruses

2000 • 167 citations

DNA Vaccine Expressing Conserved Influenza Virus Proteins Protective Against H5N1 Challenge Infection in Mice

2002 • 162 citations

Continued Circulation in China of Highly Pathogenic Avian Influenza Viruses Encoding the Hemagglutinin Gene Associated with the 1997 H5N1 Outbreak in Poultry and Humans

2000 • 161 citations

Characterization of Influenza A/HongKong/156/97 (H5N1) Virus in a Mouse Model and Protective Effect of Zanamivir on H5N1 Infection in Mice

1998 • 150 citations

Baculovirus-derived hemagglutinin vaccines protect against lethal influenza infections by avian H5 and H7 subtypes

1999 • 139 citations

From lethal virus to life-saving vaccine: developing inactivated vaccines for pandemic influenza

2004 • 138 citations

DNA Vaccine Encoding Hemagglutinin Provides Protective Immunity against H5N1 Influenza Virus Infection in Mice

1999 • 134 citations

Recombinant Influenza A Virus Vaccines for the Pathogenic Human A/Hong Kong/97 (H5N1) Viruses

1999 • 130 citations

Atypical Avian Influenza (H5N1)

2004 • 127 citations

Influenza-associated encephalopathy in Japan

2002 • 103 citations

Avian Influenza — A Challenge to Global Health Care Structures

2004 • 102 citations

Lack of H5N1 Avian Influenza Transmission to Hospital Employees, Hanoi, 2004

2005 • 92 citations

Avirulent Avian Influenza Virus as a Vaccine Strain against a Potential Human Pandemic

1999 • 90 citations

The Global Agenda on Influenza Surveillance and Control

2003 • 83 citations

Neurotropism of the 1997 Hong Kong H5N1 influenza virus in mice

2003 • 79 citations

Neurovirulence in Mice of H5N1 Influenza Virus Genotypes Isolated from Hong Kong Poultry in 2001

2003 • 76 citations

Failure to Detect Hemagglutination-Inhibiting Antibodies with Intact Avian Influenza Virions

1982 • 69 citations

Efficacy of H5 Influenza Vaccines Produced by Reverse Genetics in a Lethal Mouse Model

2005 • 68 citations

Seroprevalence of Anti-H5 Antibody among Thai Health Care Workers after Exposure to Avian Influenza (H5N1) in a Tertiary Care Center

2004 • 60 citations

Efficacy of Zanamivir against Avian Influenza A Viruses That Possess Genes Encoding H5N1 Internal Proteins and Are Pathogenic in Mammals

2001 • 59 citations

Latex Agglutination Test for Monitoring Antibodies to Avian Influenza Virus Subtype H5N1

2005 • 24 citations

Influenza A pandemics of the 20th century with special reference to 1918: virology, pathology and epidemiology

2000 • 21 citations

DNA Vaccine Expressing Conserved Influenza Virus Proteins Protective Against H5N1 Challenge Infection in Mice

2002 • 14 citations