Lysophosphatidic Acid Induces Focal Adhesion Assembly through Rho/Rho-Associated Kinase Pathway in Human Ovarian Cancer Cells

Rho GTPases and the Actin Cytoskeleton

1998 • 6,129 citations

Integrins and Signal Transduction Pathways: the Road Taken

1995 • 3,002 citations

Regulation of Myosin Phosphatase by Rho and Rho-Associated Kinase (Rho-Kinase)

1996 • 2,843 citations

Phosphorylation and Activation of Myosin by Rho-associated Kinase (Rho-kinase)

1996 • 1,964 citations

Rho-stimulated contractility drives the formation of stress fibers and focal adhesions.

1996 • 1,614 citations

Tumor Cell Interactions with the Extracellular Matrix During Invasion and Metastasis

1993 • 1,523 citations

Signaling through focal adhesion kinase

1999 • 1,169 citations

Autophosphorylation of the Focal Adhesion Kinase, ppl25^FAK, Directs SH2-Dependent Binding of pp60^src

1994 • 1,168 citations

High resistance to cisplatin in human ovarian cancer cell lines is associated with marked increase of glutathione synthesis.

1992 • 912 citations

Autophosphorylation of the focal adhesion kinase, pp125FAK, directs SH2-dependent binding of pp60src.

1994 • 844 citations

Bidirectional signaling between the cytoskeleton and integrins

1999 • 765 citations

Lysophosphatidic Acid as a Potential Biomarker for Ovarian and Other Gynecologic Cancers

1998 • 642 citations

An essential part for Rho–associated kinase in the transcellular invasion of tumor cells

1999 • 609 citations

Regulation and Functions of Rho-Associated Kinase

2000 • 500 citations

The Molecular Architecture of Focal Adhesions

1995 • 479 citations

Myosin light chain kinase-regulated endothelial cell contraction: the relationship between isometric tension, actin polymerization, and myosin phosphorylation.

1995 • 451 citations

Lysophosphatidic Acid Receptors

2000 • 404 citations

Induced Focal Adhesion Kinase (FAK) Expression in FAK-Null Cells Enhances Cell Spreading and Migration Requiring Both Auto- and Activation Loop Phosphorylation Sites and Inhibits Adhesion-Dependent Tyrosine Phosphorylation of Pyk2

1999 • 395 citations

Characterization of an ovarian cancer activating factor in ascites from ovarian cancer patients.

1995 • 325 citations

Biology of tumour metastasis

1992 • 312 citations

Platelets and cancer metastasis: A causal relationship?

1992 • 289 citations

Molecular Cloning Of Human Paxillin, a Focal Adhesion Protein Phosphorylated by P210BCR/ABL

1995 • 275 citations

Lysophosphatidic Acid Induction of Vascular Endothelial Growth Factor Expression in Human Ovarian Cancer Cells

2001 • 245 citations

Inhibition of BAD phosphorylation either at serine 112 via extracellular signal-regulated protein kinase cascade or at serine 136 via Akt cascade sensitizes human ovarian cancer cells to cisplatin.

2000 • 245 citations

Stress fiber organization regulated by MLCK and Rho-kinase in cultured human fibroblasts

2001 • 236 citations

Induction of in Vitro Tumor Cell Invasion of Cellular Monolayers by Lysophosphatidic Acid or Phospholipase D

1993 • 185 citations

Small GTP-binding Protein Rho Stimulates the Actomyosin System, Leading to Invasion of Tumor Cells

1998 • 160 citations

Cell motility mediated by rho and rho-associated protein kinase plays a critical role in intrahepatic metastasis of human hepatocellular carcinoma

1999 • 159 citations

Tyrosine phosphorylation of paxillin alpha is involved in temporospatial regulation of paxillin-containing focal adhesion formation and F-actin organization in motile cells.

2000 • 122 citations

Prospective on ovarian cancer: Why prevent?

1995 • 111 citations

Tyrosine Phosphorylation of Paxillin α Is Involved in Temporospatial Regulation of Paxillin-containing Focal Adhesion Formation and F-actin Organization in Motile Cells

2000 • 103 citations

Myosin Light Chain Phosphorylation in Neutrophil-Stimulated Coronary Microvascular Leakage

2002 • 95 citations

Dual mechanisms for lysophospholipid induction of proliferation of human breast carcinoma cells.

1999 • 92 citations

Lysophosphatidic acid induces tyrosine phosphorylation and activation of MAP‐kinase and focal adhesion kinase in cultured Swiss 3T3 cells

1993 • 78 citations

The Rho-ADP-ribosylating C3 exoenzyme from Clostridium botulinum and related C3-like transferases

2001 • 72 citations

Involvement of Focal Adhesion Kinase in Inhibition of Motility of Human Breast Cancer Cells by Sphingosine 1-Phosphate

1999 • 70 citations

Phosphorylation of Paxillin via the ERK Mitogen-activated Protein Kinase Cascade in EL4 Thymoma Cells

2000 • 59 citations

Human and rat alveolar macrophages express multiple EDG receptors

2001 • 52 citations

Involvement of phosphorylation of tyr‐31 and tyr‐118 of paxillin in MM1 cancer cell migration

2001 • 52 citations

Involvement of small GTPases Rho and Rac in the invasion of rat ascites hepatoma cells.

1999 • 33 citations

Calyculin‐A induces focal adhesion assembly and tyrosine phosphorylation of p125^Fak, p130^Cas, and paxillin in Swiss 3T3 cells

2001 • 33 citations