In VivoPertussis Toxin Administration: Effects on the Function and Levels of G_iαProteins and Their Messenger Ribonucleic Acids

A Rapid and Sensitive Method for the Quantitation of Microgram Quantities of Protein Utilizing the Principle of Protein-Dye Binding

1976 • 225,752 citations

Molecular Cloning: A Laboratory Manual

2001 • 133,517 citations

G PROTEINS: TRANSDUCERS OF RECEPTOR-GENERATED SIGNALS

1987 • 6,374 citations

A highly sensitive adenylate cyclase assay

1974 • 4,213 citations

G proteins and dual control of adenylate cyclase

1984 • 1,811 citations

Roles of G protein subunits in transmembrane signalling

1988 • 794 citations

Signal transduction by guanine nucleotide binding proteins

1987 • 362 citations

Antibodies directed against synthetic peptides distinguish between GTP-binding proteins in neutrophil and brain.

1987 • 356 citations

The G protein-gated atrial K+ channel is stimulated by three distinct GIα-subunits

1988 • 306 citations

P2-purinergic receptors are coupled to two signal transduction systems leading to inhibition of cAMP generation and to production of inositol trisphosphate in rat hepatocytes.

1987 • 213 citations

Cyclic AMP stabilizes the mRNA for phosphoenolpyruvate carboxykinase (GTP) against degradation.

1988 • 165 citations

Localization of mRNAs encoding the α‐subunits of signal‐transducing G‐proteins within rat brain and among peripheral tissues

1987 • 130 citations

Modification of the rat adipocyte A1 adenosine receptor-adenylate cyclase system during chronic exposure to an A1 adenosine receptor agonist: alterations in the quantity of GS alpha and Gi alpha are not associated with changes in their mRNAs.

1989 • 120 citations

Cholera toxin ADP-ribosylates the islet-activating protein substrate in adipocyte membranes and alters its function.

1985 • 81 citations

The glucocorticoid dexamethasone inhibits synthesis of interferon by decreasing the level of its mRNA.

1988 • 75 citations

The new cardiotonic agent sulmazole is an A1 adenosine receptor antagonist and functionally blocks the inhibitory regulator, Gi.

1988 • 74 citations

Multiple components of the A1 adenosine receptor-adenylate cyclase system are regulated in rat cerebral cortex by chronic caffeine ingestion.

1988 • 72 citations

Molecular cloning of a new human G protein Evidence for two G_iα‐like protein families

1987 • 70 citations

Reciprocal modulation of agonist and antagonist binding to A1 adenosine receptors by guanine nucleotides is mediated via a pertussis toxin-sensitive G protein.

1988 • 52 citations

Kinetics of adenosinediphosphoribosylation of elongation factor 2 in cells exposed to diphtheria toxin

1981 • 44 citations

Chronic Exposure to Pertussis Toxin Alters Muscarinic Receptor‐Mediated Regulation of Cyclic AMP Metabolism in Neuroblastoma × Glioma NG108–15 Hybrid Cells

1988 • 7 citations