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Hypoxic Sensitizers — Implications for Radiation Therapy

Data up to Jan 2025

Published1979
Citations209
References31

Total Citations Per Year

Abstract

References (31)

Radiation and High-Dose Metronidazole in Supratentorial Glioblastomas

1976 • 309 citations

Clinical testing of the radiosensitizer Ro 07-0582: Experience with multiple doses

1977 • 264 citations

Electron Affinic Sensitization: V. Radiosensitization of Hypoxic Bacteria and Mammalian Cells in Vitro by Some Nitroimidazoles and Nitropyrazoles

1974 • 229 citations

Hydrated electrons and radiobiological sensitisation

1963 • 211 citations

Electron-affinic Sensitization

1969 • 207 citations

Hypoxic Sensitizers: Radiobiological Studies at the Cellular Level

1975 • 205 citations

Mode of Action of Nitrofurazone

1970 • 193 citations

Selective chemotherapy of noncycling cells in an in vitro tumor model.

1974 • 170 citations

Radiosensitizers of hypoxic cells in solid tumours

1976 • 168 citations

CHEMICAL RADIOSENSITIZATION OF HYPOXIC CELLS

1973 • 166 citations

Selective Radiosensitization of the Hypoxic Cells of Mouse Tumors with the Nitroimidazoles Metronidazole and Ro 7-0582

1975 • 128 citations

Clinical testing of the radiosensitiser Ro-07-0582 I. dose tolerance, serum and tumour concentrations

1976 • 125 citations

Metronidazole (“Flagyl”). A radiosensitizer of hypoxic cells

1974 • 118 citations

Clinical Phase I Study of the Hypoxic Cell Radiosensitizer RO-07-0582, A 2-Nitroimidazole Derivative

1977 • 116 citations

Tests of Two Electron-Affinic Radiosensitizers in Vivo Using Regrowth of an Experimental Carcinoma

1975 • 115 citations

Radiosensitization of Mammalian Cells byP-nitroacetophenone

1973 • 107 citations

Chemotherapeutic Properties of Heterocyclic Compounds: Monocyclic Compounds with Five-Membered Rings

1973 • 105 citations

Metronidazole (‘Flagyl’): Mechanisms of Radiosensitization

1974 • 103 citations

Nitrofurans as radiosensitizers of hypoxic mammalian cells.

1972 • 99 citations

Hypoxic Cells in anin VitroTumour Model

1973 • 96 citations

Effectiveness of nitrofuran derivatives in sensitizing hypoxic mammalian cells to X rays

1973 • 95 citations

Phase 1 Study of High-Dose Metronidazole: A SpecificIn VivoandIn VitroRadiosensitizer of Hypoxic Cells

1975 • 81 citations

In vivotesting of hypoxic radiosensitizers using the KHT murine tumour assayed by the lung-colony technique

1975 • 73 citations

Metronidazole (Flagyl): characterization as a cytotoxic drug specific for hypoxic tumour cells

1976 • 70 citations

Radiation Chemical Studies with Nitrofurazone as Related to Its Mechanism of Radiosensitization

1973 • 47 citations

Tumor and Normal Tissue Response to Metronidazole and Irradiation in Mice

1974 • 43 citations

Serum concentration measurements in man of the radiosensitizer Ro-07-0582: some preliminary results

1975 • 40 citations

The Response of a Transplantable Tumor to Fractionated Irradiation: 1. X Rays and the Hypoxic Cell Radiosensitizer Ro-07-0582

1976 • 40 citations

Radiosensitization of Mammalian Cells byp-Nitroacetophenone

1972 • 39 citations

Radiosensitization of C3H mouse mammary tumours using fractionated doses of X rays with the drug Ro-07–0582

1976 • 30 citations

Chemotherapy of Cancer

1978 • 6 citations

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Hypoxic Sensitizers — Implications for Radiation Therapy (1979) – New England Journal of Medicine | Metascience Observatory Explorer