The omega/lambda 5 surrogate immunoglobulin light chain is expressed on the surface of transitional B lymphocytes in murine bone marrow.

Molecular components of the B-cell antigen receptor complex of the IgM class

1990 • 401 citations

The proteins encoded by the VpreB and lambda 5 pre-B cell-specific genes can associate with each other and with mu heavy chain.

1990 • 352 citations

A second gene, VpreB in the lambda 5 locus of the mouse, which appears to be selectively expressed in pre-B lymphocytes.

1987 • 306 citations

λ5, a new light-chain-related locus selectively expressed in pre-B lymphocytes

1986 • 302 citations

B lymphocyte lineage-restricted expression of mb-1, a gene with CD3-like structural properties.

1988 • 283 citations

Transmission and expression of a specific pair of rearranged immunoglobulin μ and κ genes in a transgenic mouse line

1985 • 244 citations

Immunoglobulin synthesis by lymphoid cells transformed in vitro by Abelson murine leukemia virus

1979 • 243 citations

The products of pre-B cell-specific genes (lambda 5 and VpreB) and the immunoglobulin mu chain form a complex that is transported onto the cell surface.

1990 • 221 citations

A novel 34-kd protein co-isolated with the IgM molecule in surface IgM-expressing cells.

1988 • 209 citations

Evidence that murine pre-B cells synthesise μ heavy chains but no light chains

1979 • 208 citations

B lymphocyte antigen receptors (mIg) are non-covalently associated with a disulfide linked, inducibly phosphorylated glycoprotein complex.

1990 • 208 citations

B29: a member of the immunoglobulin gene superfamily exclusively expressed on beta-lineage cells.

1988 • 197 citations

Formation of disulphide-linked µ2ω2 tetramers in pre-B cells by the 18K ω-immunoglobulin light chain

1987 • 179 citations

Regulated progression of a cultured pre-B-cell line to the B-cell stage

1985 • 174 citations

A transgenic immunoglobulin Mu gene prevents rearrangement of endogenous genes

1985 • 169 citations

Two new acute lymphoblastic leukemia cell lines with early B-cell phenotypes

1982 • 141 citations

Feedback inhibition of immunoglobulin gene rearrangement by membrane mu, but not by secreted mu heavy chains.

1988 • 138 citations

Mu heavy chains can associate with a pseudo-light chain complex (ψL) in human pre-B cell lines

1989 • 105 citations

Frequent lambda light chain gene rearrangement and expression in a Ly-1 B lymphoma with a productive kappa chain allele.

1986 • 78 citations

Isolation of a cDNA copy of an RNA species expressed in murine pre-B cells.

1986 • 78 citations

Two types of mu chain complexes are expressed during differentiation from pre-B to mature B cells.

1990 • 76 citations

Immunoglobulin lambda light-chain-related genes 14.1 and 16.1 are expressed in pre-B cells and may encode the human immunoglobulin omega light-chain protein.

1989 • 71 citations

Myristoylation and the post-translational acquisition of hydrophobicity by the membrane immunoglobulin heavy-chain polypeptide in B lymphocytes.

1987 • 59 citations

Independent control of immunoglobulin heavy and light chain expression in a murine pre-B-cell line

1981 • 58 citations

The Omega and Iota Surrogate Immunoglobulin Light Chains

1988 • 56 citations

Allelic exclusion in transgenic mice carrying mutant human IgM genes.

1988 • 42 citations

Bone marrow pre-B lymphocytes synthesize immunoglobulin mu chains of membrane type with different properties and intracellular pathways.

1985 • 31 citations

Two new acute lymphoblastic leukemia cell lines with early B-cell phenotypes

1982 • 21 citations

Analysis of surface mu-chain expression in human lymphoblastoid cell lines that do not produce light chains.

1984 • 16 citations