Closing in on Genes for Manic-Depressive Illness and Schizophrenia

The Future of Genetic Studies of Complex Human Diseases

1996 • 5,355 citations

Genetic dissection of complex traits: guidelines for interpreting and reporting linkage results

1995 • 5,291 citations

Genetic Dissection of Complex Traits

1994 • 3,497 citations

Effect of Chlorpromazine or Haloperidol on Formation of 3‐Methoxytyramine and Normetanephrine in Mouse Brain

1963 • 2,148 citations

Linkage strategies for genetically complex traits. I. Multilocus models.

1990 • 1,335 citations

Linkage of a neurophysiological deficit in schizophrenia to a chromosome 15 locus

1997 • 1,142 citations

A Family Study of Schizoaffective, Bipolar I, Bipolar II, Unipolar, and Normal Control Probands

1982 • 995 citations

Linkage strategies for genetically complex traits. II. The power of affected relative pairs.

1990 • 886 citations

Recent Advances in the Molecular Biology of Dopamine Receptors

1993 • 768 citations

Mendelian Inheritance in Man: A Catalog of Human Genes and Genetic Disorders

1998 • 693 citations

The affected-pedigree-member method of linkage analysis.

1988 • 493 citations

A potential vulnerability locus for schizophrenia on chromosome 6p24–22: evidence for genetic heterogeneity

1995 • 465 citations

An international two–stage genome–wide search for schizophrenia susceptibility genes

1995 • 385 citations

Chromosome 18 DNA markers and manic-depressive illness: evidence for a susceptibility gene.

1994 • 378 citations

Evidence for linkage of bipolar disorder to chromosome 18 with a parent-of-origin effect.

1995 • 347 citations

Genome screening by searching for shared segments: mapping a gene for benign recurrent intrahepatic cholestasis

1994 • 325 citations

A possible vulnerability locus for bipolar affective disorder on chromosome 21q22.3

1994 • 320 citations

Evaluation of a susceptibility gene for schizophrenia on chromosome 6p by multipoint affected sib–pair linkage analysis

1995 • 279 citations

A locus for bipolar affective disorder on chromosome 4p

1996 • 272 citations

Genetic mapping using haplotype, association and linkage methods suggests a locus for severe bipolar disorder (BPI) at 18q22-q23

1996 • 260 citations

Evidence for a susceptibility locus for schizophrenia on chromosome 6pter–p22

1995 • 251 citations

The generalized sib pair IBD distribution: its use in the detection of linkage

1978 • 244 citations

Dopamine D4 receptor repeat: analysis of different native and mutant forms of the human and rat genes.

1994 • 238 citations

Affected-sib-pair interval mapping and exclusion for complex genetic traits: Sampling considerations

1996 • 225 citations

High-resolution genetic mapping of complex traits.

1995 • 220 citations

A manic depressive history

1996 • 211 citations

Linkage disequilibrium mapping of a type 1 diabetes susceptibility gene (IDDM7) to chromosome 2q31–q33

1995 • 211 citations

Genes with triplet repeats: candidate mediators of neuropsychiatric disorders

1993 • 187 citations

Eye tracking dysfunction is a putative phenotypic susceptibility marker of schizophrenia and maps to a locus on chromosome 6p in families with multiple occurrence of the disease

1996 • 185 citations

Trinucleotide repeat expansion in neurological disease

1994 • 185 citations

Additional support for schizophrenia linkage on chromosomes 6 and 8: A multicenter study

1996 • 184 citations

No Structural Mutation in the Dopamine D2 Receptor Gene in Alcoholism or Schizophrenia

1994 • 182 citations

Mapping quantitative trait loci with extreme discordant sib pairs: sampling considerations.

1996 • 176 citations

A genome-wide search for chromosomal loci linked to bipolar affective disorder in the Old Order Amish

1996 • 173 citations

Association of dopamine D2 receptor molecular variant with schizophrenia

1994 • 172 citations

Chromosome 18 DNA markers and manic-depressive illness : evidence for a susceptibility gene

1994 • 169 citations

Mendelian inheritance in man: A catalog of human genes and genetic disorders

1996 • 145 citations

Allelic association between a Ser-9-Gly polymorphism in the dopamine D3 receptor gene and schizophrenia

1996 • 144 citations

Functional Analysis of the Human D2 Dopamine Receptor Missense Variants

1996 • 125 citations

Affected-sib-pair analyses reveal support of prior evidence for a susceptibility locus for bipolar disorder, on 21q.

1996 • 124 citations

Distribution of a novel mutation in the first exon of the human dopamine D4 receptor gene in psychotic patients

1993 • 124 citations

A Linkage Study of Bipolar Illness

1997 • 118 citations

Candidate genes in psychiatry: An epidemiological perspective

1993 • 108 citations

Multifactorial inheritance in type 1 diabetes

1995 • 95 citations

Two-Locus Admixture Linkage Analysis of Bipolar and Unipolar Affective Disorder Supports the Presence of Susceptibility Loci on Chromosomes 11p15 and 21q22

1997 • 93 citations

Linkage analysis of families with bipolar illness and chromosome 18 markers

1996 • 79 citations

Commentary:The role of meta-analysis in linkage studies of complex traits

1997 • 60 citations

Analysis of chromosome 18 DNA markers in multiplex pedigrees with manic depression

1996 • 57 citations

No Abnormality in the Gene for the G Protein Stimulatory α Subunit in Patients With Bipolar Disorder

1997 • 50 citations

1996 William Allan Award Address. Algorithms and inferences: the challenge of multifactorial diseases.

1997 • 41 citations

Searching for susceptibility genes in schizophrenia by genetic linkage analysis.

1996 • 35 citations

No structural mutation in the dopamine D2 receptor gene in alcoholism or schizophrenia. Analysis using denaturing gradient gel electrophoresis

1994 • 34 citations

Improvement of the power to detect complex disease genes by regional inference procedures

1997 • 19 citations

Molecular Genetic Approaches to the Analysis and Diagnosis of Human Inherited Disease: An Overview

1992 • 19 citations

Description of the Genetic Analysis Workshop 10 bipolar disorder linkage data sets

1997 • 17 citations

Allelic association between a Ser-9-Gly polymorphism in the dopamine D3 receptor gene and schizophrenia

1996 • 16 citations

Linkage studies of bipolar disorder to chromosome 18 markers

1996 • 11 citations

The dopamine hypothesis of schizophrenia

1990 • 6 citations

Bipolar disorder and chromosome 18: An analysis of multiple data sets

1997 • 4 citations

Genetics of Psychiatric Disorders

2014 • 3 citations

Description of the Genetic Analysis Workshop 10 bipolar disorder linkage data sets

1997 • 2 citations

Improvement of the power to detect complex disease genes by regional inference procedures

1997 • 2 citations

Recent developments in genetics of bipolar illness.

1995 • 2 citations