Evidence for Decreased DARPP-32 in the Prefrontal Cortex of Patients With Schizophrenia

Electrophoretic transfer of proteins from polyacrylamide gels to nitrocellulose sheets: procedure and some applications.

1979 • 54,907 citations

Parallel Organization of Functionally Segregated Circuits Linking Basal Ganglia and Cortex

1986 • 8,208 citations

Dopamine Receptor Binding Predicts Clinical and Pharmacological Potencies of Antischizophrenic Drugs

1976 • 2,224 citations

Gene Expression for Glutamic Acid Decarboxylase Is Reduced Without Loss of Neurons in Prefrontal Cortex of Schizophrenics

1995 • 1,007 citations

Abnormally High Neuronal Density in the Schizophrenic Cortex

1995 • 866 citations

Beyond the Dopamine Receptor

1999 • 742 citations

Prefrontal Dopamine D₁Receptors and Working Memory in Schizophrenia

2002 • 724 citations

Decreased prefrontal dopamine D1 receptors in schizophrenia revealed by PET

1997 • 707 citations

Brain receptors for antipsychotic drugs and dopamine: direct binding assays.

1975 • 695 citations

Altered Distribution of Nicotinamide-Adenine Dinucleotide Phosphate—Diaphorase Cells in Frontal Lobe of Schizophrenics Implies Disturbances of Cortical Development

1993 • 660 citations

DARPP-32, a dopamine- and adenosine 3':5'-monophosphate-regulated phosphoprotein enriched in dopamine-innervated brain regions. III. Immunocytochemical localization

1984 • 652 citations

DARPP-32, a dopamine-regulated neuronal phosphoprotein, is a potent inhibitor of protein phosphatase-1

1984 • 610 citations

Modulation of calcium currents by a D1 dopaminergic protein kinase/phosphatase cascade in rat neostriatal neurons

1995 • 542 citations

Dopamine D1 receptor mutant mice are deficient in striatal expression of dynorphin and in dopamine-mediated behavioral responses

1994 • 490 citations

DARPP-32: Regulator of the Efficacy of Dopaminergic Neurotransmission

1998 • 474 citations

Selective alterations in gene expression for NMDA receptor subunits in prefrontal cortex of schizophrenics

1996 • 440 citations

Bidirectional Regulation of DARPP-32 Phosphorylation by Dopamine

1997 • 416 citations

Glutamate receptor expression in schizophrenic brain

2000 • 401 citations

Association of ketamine-induced psychosis with focal activation of the prefrontal cortex in healthy volunteers

1997 • 393 citations

Activation of NMDA receptors induces dephosphorylation of DARPP-32 in rat striatal slices

1990 • 356 citations

A dopamine- and cyclic AMP-regulated phosphoprotein enriched in dopamine-innervated brain regions

1983 • 342 citations

A Dopamine/D1 Receptor/Protein Kinase A/Dopamine- and cAMP-Regulated Phosphoprotein (M_r32 kDa)/Protein Phosphatase-1 Pathway Regulates Dephosphorylation of the NMDA Receptor

1998 • 322 citations

Regulation of Phosphorylation of the GluR1 AMPA Receptor in the Neostriatum by Dopamine and PsychostimulantsIn Vivo

2000 • 303 citations

DARPP-32, a dopamine- and adenosine 3':5'-monophosphate-regulated phosphoprotein enriched in dopamine-innervated brain regions. I. Regional and cellular distribution in the rat brain

1984 • 303 citations

Inhibition by dopamine of (Na+ + K+)ATPase activity in neostriatal neurons through D1 and D2 dopamine receptor synergism

1990 • 286 citations

A calcium/calmodulin-dependent protein kinase from mammalian brain that phosphorylates Synapsin I: partial purification and characterization

1983 • 265 citations

Evidence for a compromised dorsolateral prefrontal cortical parallel circuit in schizophrenia

2000 • 206 citations

Regulation of the phosphorylation of the dopamine- and cAMP-regulated phosphoprotein of 32 kDa in vivo by dopamine D ₁ , dopamine D ₂ , and adenosine A _2A receptors

2000 • 193 citations

A common action of clozapine, haloperidol, and remoxipride on D1- and D2-dopaminergic receptors in the primate cerebral cortex.

1994 • 175 citations

Significant reductions in synapsin but not synaptophysin specific activity in the brains of some schizophrenics

1993 • 157 citations

Dopamine D1 receptor modulates the voltage‐gated sodium current in rat striatal neurones through a protein kinase A.

1995 • 154 citations

D₁ Dopamine Receptor Activation Reduces GABA_A Receptor Currents in Neostriatal Neurons Through a PKA/DARPP-32/PP1 Signaling Cascade

2000 • 147 citations

Down-regulation of the D1 and D5 dopamine receptors in the primate prefrontal cortex by chronic treatment with antipsychotic drugs.

1997 • 129 citations

Immunocytochemical localization of DARPP‐32, a dopamine and cyclic‐ AMP‐regulated phosphoprotein, in the primate brain

1992 • 81 citations

DARPP‐32, a phosphoprotein enriched in dopaminoceptive neurons bearing dopamine D1 receptors: DIstribution in the cerebral cortex of the newborn and adult rhesus monkey

1990 • 71 citations

Age-related abnormalities in expression of mRNAs encoding synapsin 1A, synapsin 1B, and synaptophysin in the temporal cortex of schizophrenics

1997 • 49 citations

A method for fixation of previously fresh-frozen human adult and fetal brains that preserves histological quality and immunoreactivity

1992 • 45 citations

Schizophrenia: elevated mRNA for calcium-calmodulin-dependent protein kinase IIβ in frontal cortex

2000 • 31 citations

Distribution of messenger RNAs for D1 dopamine receptors and DARPP-32 in striatum and cerebral cortex of the cynomolgus monkey: Relationship to D1 dopamine receptors

1995 • 29 citations

Chronic Treatment of Rats with SCH‐23390 or Raclopride Does Not Affect the Concentrations of DARPP‐32 or Its mRNA in Dopamine‐Innervated Brain Regions

1990 • 28 citations

Protein phosphorylation systems in postmortem human brain

1989 • 11 citations