Effects of gender and menopausal status on the association of apolipoprotein E phenotype with plasma lipoprotein levels. Results from the Framingham Offspring Study.

Estimation of the Concentration of Low-Density Lipoprotein Cholesterol in Plasma, Without Use of the Preparative Ultracentrifuge

1972 • 31,801 citations

Gene Dose of Apolipoprotein E Type 4 Allele and the Risk of Alzheimer's Disease in Late Onset Families

1993 • 8,888 citations

Dextran sulfate-Mg2+ precipitation procedure for quantitation of high-density-lipoprotein cholesterol.

1982 • 2,206 citations

Apolipoprotein E polymorphism and atherosclerosis.

1988 • 2,007 citations

AN INVESTIGATION OF CORONARY HEART DISEASE IN FAMILIES

1979 • 1,607 citations

Effects of Postmenopausal Estrogen Replacement on the Concentrations and Metabolism of Plasma Lipoproteins

1991 • 1,158 citations

Lipoprotein receptors and cholesterol homeostasis

1983 • 755 citations

Role of the apolipoprotein E polymorphism in determining normal plasma lipid and lipoprotein variation.

1985 • 714 citations

Abnormal lipoprotein receptor-binding activity of the human E apoprotein due to cysteine-arginine interchange at a single site.

1982 • 674 citations

Increased binding of low density lipoprotein to liver membranes from rats treated with 17 alpha-ethinyl estradiol.

1979 • 571 citations

Human very low density lipoprotein apolipoprotein E isoprotein polymorphism is explained by genetic variation and posttranslational modification

1981 • 568 citations

Automated enzymatic standardized lipid analyses for plasma and lipoprotein fractions

1987 • 529 citations

The apolipoprotein E polymorphism: a comparison of allele frequencies and effects in nine populations.

1991 • 507 citations

Lipoprotein(a) is an independent risk factor for myocardial infarction at a young age

1990 • 431 citations

Apolipoprotein E polymorphism in the Finnish population: gene frequencies and relation to lipoprotein concentrations.

1987 • 410 citations

Polymorphism of apolipoprotein E

1979 • 405 citations

Effect of gender, age, and lipid status on low density lipoprotein subfraction distribution. Results from the Framingham Offspring Study.

1987 • 395 citations

Abnormal in vivo metabolism of apolipoprotein E4 in humans.

1986 • 343 citations

Familial apolipoprotein E deficiency.

1986 • 300 citations

Type III Hyperlipoproteinemia Associated with Apolipoprotein E Deficiency

1981 • 272 citations

Genetics of the apolipoprotein E system in man.

1980 • 268 citations

The Biochemical, Clinical, and Genetic Features of Type III Hyperlipoproteinemia

1975 • 260 citations

Effects of age, gender, and menopausal status on plasma low density lipoprotein cholesterol and apolipoprotein B levels in the Framingham Offspring Study.

1994 • 254 citations

Polymorphism at the Apoprotein‐E locus in relation to risk of coronary disease

1984 • 254 citations

Simultaneous effects of the apolipoprotein E polymorphism on apolipoprotein E, apolipoprotein B, and cholesterol metabolism.

1988 • 252 citations

Relation of apolipoprotein E phenotype to myocardial infarction and mortality from coronary artery disease

1993 • 249 citations

Apolipoprotein C-I modulates the interaction of apolipoprotein E with beta-migrating very low density lipoproteins (beta-VLDL) and inhibits binding of beta-VLDL to low density lipoprotein receptor-related protein.

1990 • 239 citations

Defects in the low density lipoprotein receptor gene affect lipoprotein (a) levels: multiplicative interaction of two gene loci associated with premature atherosclerosis.

1989 • 239 citations

LDL particle size distribution. Results from the Framingham Offspring Study.

1992 • 229 citations

Clearance of chylomicron remnants by the low density lipoprotein receptor-related protein/alpha 2-macroglobulin receptor

1991 • 210 citations

Apolipoprotein E phenotypes in Finnish youths: a cross-sectional and 6-year follow-up study.

1990 • 205 citations

The use of measured genotype information in the analysis of quantitative phenotypes in man. II. The role of the apolipoprotein E polymorphism in determining levels, variability, and covariability of cholesterol, betalipoprotein, and triglycerides in a sample of unrelated individuals

1987 • 205 citations

Overexpression of human low density lipoprotein receptors leads to accelerated catabolism of Lp(a) lipoprotein in transgenic mice.

1990 • 188 citations

Apolipoprotein E phenotyping with a single gel method: application to the study of informative matings.

1983 • 178 citations

Cholesterol absorption, elimination, and synthesis related to LDL kinetics during varying fat intake in men with different apoprotein E phenotypes.

1992 • 175 citations

Apolipoprotein E phenotypes in patients with myocardial infarction

1984 • 156 citations

Chylomicron remnant clearance from the plasma is normal in familial hypercholesterolemic homozygotes with defined receptor defects.

1990 • 151 citations

Influence of apolipoprotein E polymorphism on apolipoprotein B-100 metabolism in normolipemic subjects.

1991 • 146 citations

Influences of common variants of apolipoprotein E on measures of lipid metabolism in a sample selected for health.

1991 • 143 citations

Enzyme-linked immunosorbent assay for human plasma apolipoprotein B

1987 • 119 citations

Apo E allele frequencies in younger (age 42–50) vs older (age 65–90) women

1993 • 114 citations

Serum lipoprotein(a) in patients heterozygous for familial hypercholesterolemia, their relatives, and unrelated control populations.

1991 • 109 citations

Effects of estrogen replacement on plasma lipoproteins and apolipoproteins in postmenopausal, dyslipidemic women

1992 • 105 citations

Effects of apoprotein E polymorphism on serum lipoprotein concentration.

1985 • 82 citations

Impact of apolipoprotein E polymorphism in determining interindividual variation in total cholesterol and low density lipoprotein cholesterol in Hispanics and non-Hispanic whites

1993 • 81 citations

Apolipoprotein E polymorphism affects plasma levels of lipoprotein(a)

1991 • 79 citations

Effects of low dose oral contraceptives on very low density and low density lipoprotein metabolism.

1993 • 76 citations

Bias of the contribution of single-locus effects to the variance of a quantitative trait.

1986 • 71 citations

Differences in apolipoproteins and low-density lipoprotein subfractions in postmenopausal women on and off estrogen therapy: Results from the Framingham Offspring Study

1990 • 59 citations

Phenotypic effects of apolipoprotein structural variation on lipid profiles. III. Contribution of apolipoprotein E phenotype to prediction of total cholesterol, apolipoprotein B, and low density lipoprotein cholesterol in the healthy women study.

1990 • 57 citations

Effectiveness of Diet and Drugs in the Treatment of Patients with Elevated Lp(a) Levels

1990 • 52 citations

Gender differences in a Type 2 (non-insulin-dependent) diabetic population with respect to apolipoprotein E phenotype frequencies

1993 • 18 citations