Investigation of the Effect of Growth Environment on the Stability of Low-copy-number Plasmids in Escherichia coli.

Multimerization of high copy number plasmids causes instability: Cole 1 encodes a determinant essential for plasmid monomerization and stability

1984 • 443 citations

Partitioning of bacterial plasmids during cell division: a cis-acting locus that accomplishes stable plasmid inheritance

1980 • 335 citations

Transcription from efficient promoters can interfere with plasmid replication and diminish expression of plasmid specified genes.

1982 • 281 citations

Specific-purpose plasmid cloning vectors I. Low copy number, temperature-sensitive, mobilization-defective pSC101-derived containment vectors

1981 • 198 citations

The Influence of the Growth Environment on the Stability of a Drug Resistance Plasmid in Escherichia coli K12

1979 • 189 citations

Maintenance and genetic stability of vector plasmids pBR322 and pBR325 in Escherichia coli K12 strains grown in a chemostat

1981 • 141 citations

Maintenance of some ColE1-type plasmids in chemostat culture

1980 • 126 citations

Replication of R-factor R1 in Scherichia coli K-12 at different growth rates

1975 • 108 citations

The use of a partition locus to increase stability of tryptophan-operon-bearing plasmids in Escherichia coli

1983 • 91 citations

Stability of a cloned gene in yeast grown in chemostat culture

1983 • 88 citations

Persistence of the pBR 322 plasmid in Escherichia coli K 12 grown in chemostat cultures

1980 • 80 citations

A Mathematical Method for Analysing Plasmid Stability in Micro-organisms

1987 • 72 citations

Phenotypic Stability of trp Operon Recombinant Plasmids in Escherichia coli

1980 • 64 citations

Isolation and characterization of new copy mutants of plasmid R1, and identification of a polypeptide involved in copy number control

1981 • 64 citations

Persistence of pBR322-related plasmids inEscherichia coligrown in chemostat cultures

1984 • 61 citations

Survival of R-factor carryingEscherichia coliin mixed cultures in the chemostat

1977 • 51 citations

Investigation of the Instability of Plasmids Directing the Expression of Met-Prochymosin in Escherichia coli

1985 • 49 citations

Dual-origin plasmid vectors whose origin of replication is controlled by the coliphage lambda promoter pL

1984 • 36 citations

Loss of The Multi-Copy Resistance Plasmid pBR 325 from Escherichia Coli GY 2354 pBR 325 during Continuous Cultivation

1980 • 11 citations

Survival of R-factor carrying Escherichia coli in mixed cultures in the chemostat

1977 • 5 citations