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Metronidazole (Flagyl): Degradation by the Intestinal Flora

Data up to Jan 2025

Published1976
Citations25
References30

Total Citations Per Year

Abstract

References (30)

Intestinal Bacteria And The Hydrolysis Of Glycosidic Bonds

1971 • 320 citations

Radiation and High-Dose Metronidazole in Supratentorial Glioblastomas

1976 • 309 citations

ASSOCIATION OF GERMFREE MICE WITH BACTERIA ISOLATED FROM NORMAL MICE

1965 • 241 citations

The mode of action of metronidazole in Trichomonas vaginalis and other micro-organisms

1974 • 195 citations

Mode of Action of Nitrofurazone

1970 • 193 citations

Bactericidal Activity of Five Antimicrobial Agents against Bacteroides fragilis

1972 • 157 citations

ALTERATIONS IN THE MOUSE CECUM AND ITS FLORA PRODUCED BY ANTIBACTERIAL DRUGS

1968 • 140 citations

The Selective Toxicity of Antimicrobial Nitroheterocyclic Drugs

1973 • 127 citations

Metronidazole (“Flagyl”). A radiosensitizer of hypoxic cells

1974 • 118 citations

Radiosensitization of anoxic cells by metronidazole

1973 • 118 citations

Susceptibility of Anaerobic Bacteria to Metronidazole: Relative Resistance of Non-Spore-Forming Gram-Positive Baccilli

1975 • 108 citations

The Mode of Action of Metronidazole against Trichomonas vaginalis

1970 • 88 citations

Phase 1 Study of High-Dose Metronidazole: A SpecificIn VivoandIn VitroRadiosensitizer of Hypoxic Cells

1975 • 81 citations

Reduction of niridazole by rat liver xanthine oxidase

1971 • 74 citations

Metronidazole (Flagyl): characterization as a cytotoxic drug specific for hypoxic tumour cells

1976 • 70 citations

Effect of metronidazole on hydrogen production by Clostridium acetobutylicum

1972 • 62 citations

Metabolism of trinitrotoluene (TNT) in vitro.

1946 • 59 citations

“High-dose” metronidazole: a preliminary pharmacological study prior to its investigational use in clinical radiotherapy trials

1974 • 59 citations

Human studies with "high dose" metronidazole: a non-toxic radiosensitizer of hypoxic cells

1975 • 58 citations

METABOLISM OF THE NITROFURANS

1951 • 58 citations

The effect of iron deficiency on the stomach of the rat

1961 • 50 citations

Metronidazole (Flagyl): iron catalysed reaction with sulphydryl groups and tumour radiosensitisation

1975 • 49 citations

The effect of Flagyl on xanthine oxidase and alcohol dehydrogenase

1966 • 27 citations

Enlargement of the caecum in the rat in iron deficiency

1962 • 20 citations

Medium for the propagation and assay of lactic and other phages.

1974 • 20 citations

METRONIDAZOLE AND TISSUE ZINC/IRON RATIO IN CANCER THERAPY

1976 • 15 citations

Effects of Oral Chlortetracycline on Diarrhea and on the Dry Weights of Cleaned Intestinal Organs in Rats Fed Two Different Diets

1958 • 13 citations

METRONIDAZOLE AND IRON IN CANCER THERAPY

1976 • 12 citations

Metronidazole (flagyl), a radiosensitiser of possible clinical use in cancer chemotherapy: Some biochemical and pharmacological considerations

1976 • 10 citations

ACUTE DRUG ADMINISTRATION AND CANCER CONTROL

1974 • 6 citations

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Metronidazole (Flagyl): Degradation by the Intestinal Flora (1976) – Xenobiotica | Metascience Observatory Explorer