Metabolic studies of a podophyllotoxin derivative (VP16) in the isolated perfused liver

Effect of VP-16-213 on the intracellular degradation of DNA in HeLa cells

1976 • 197 citations

Activity of a new glycosidic lignan derivative (VP 16-213) related to podophyllotoxin in experimental tumors

1973 • 184 citations

Pharmacokinetics of high-dose etoposide (VP-16-213) administered to cancer patients.

1984 • 149 citations

Cure of Mice bearing Advanced Plasma Cell Tumours with Aniline Mustard : the Relationship between Glucuronidase Activity and Tumour Sensitivity

1966 • 139 citations

VM 26 and VP 16–213: A comparative analysis

1977 • 122 citations

Pharmacokinetics of VP16-213 given by different administration methods

1982 • 121 citations

Pharmacokinetics of teniposide (VM26) and etoposide (VP16-213) in children with cancer

1982 • 107 citations

Analysis of the anticancer drugs VP 16-213 and VM 26 and their metabolites by high-performance liquid chromatography

1980 • 90 citations

The clinical pharmacology of VM26 and VP16-213

1982 • 60 citations

High-performance liquid chromatography determination of 4′-demethyl-epipodophyllotoxin-9-(4,6-O-ethylidene β-d-glucopyranoside) (VP 16-213) in human plasma

1981 • 57 citations

Comparative cytotoxic and cytokinetic effects of the epipodophyllotoxins 4'-demethylepipodophyllotoxin-9-(4,6-O-2-ethylidene-beta-D-glucopyranoside) and 4'-demethylepipodophyllotoxin-9-(4,6-O-2-thenylidene-beta-D-glucopyranoside) and their metabolites on human leukemic lymphoblasts.

1983 • 43 citations

Pharmacokinetics of VP16-213 in Lewis lung carcinoma bearing mice

1982 • 28 citations

ETOPOSIDE: A NEW ANTI-CANCER AGENT

1981 • 26 citations

Flow-cytometric analysis of DNA distribution after VP16-213 treatment of Lewis lung carcinoma

1983 • 17 citations

Cytotoxicity of aniline mustard glucuronide alone or in a combination with glucose in Walker cells in culture and sarcoma-180 tumour bearing animals.

1983 • 2 citations