Striatal dopaminergic afferents concentrate in GDNF-positive patches during development and in developing intrastriatal striatal grafts

Renal and neuronal abnormalities in mice lacking GDNF

1996 • 1,260 citations

Renal agenesis and the absence of enteric neurons in mice lacking GDNF

1996 • 1,208 citations

Defects in enteric innervation and kidney development in mice lacking GDNF

1996 • 1,169 citations

Protection and repair of the nigrostriatal dopaminergic system by GDNF in vivo

1995 • 1,084 citations

Functional recovery in parkinsonian monkeys treated with GDNF

1996 • 955 citations

Developing motor neurons rescued from programmed and axotomy-induced cell death by GDNF

1995 • 686 citations

Mesencephalic dopaminergic neurons protected by GDNF from axotomy-induced degeneration in the adult brain

1995 • 659 citations

Dopaminergic Neurons Protected from Degeneration by GDNF Gene Therapy

1997 • 637 citations

In vivo neurotrophic effects of GDNF on neonatal and adult facial motor neurons

1995 • 593 citations

Switch in the expression of rat GABAA-receptor subtypes during postnatal development: an immunohistochemical study

1994 • 504 citations

The pre- and postnatal development of the dopaminergic cell groups in the ventral mesencephalon and the dopaminergic innervation of the striatum of the rat

1988 • 499 citations

Complementary and Overlapping Expression of Glial Cell Line-Derived Neurotrophic Factor (GDNF), c-ret Proto-Oncogene, and GDNF Receptor-α Indicates Multiple Mechanisms of Trophic Actions in the Adult Rat CNS

1997 • 494 citations

Glial Cell Line-Derived Neurotrophic Factor Is Expressed in the Developing but Not Adult Striatum and Stimulates Developing Dopamine Neurons in Vivo

1993 • 384 citations

Glial cell line-derived neurotrophic factor but not transforming growth factor beta 3 prevents delayed degeneration of nigral dopaminergic neurons following striatal 6-hydroxydopamine lesion.

1995 • 377 citations

GDNF protects nigral dopamine neurons against 6-hydroxydopamine in vivo

1995 • 374 citations

Functional neuronal replacement by grafted striatal neurones in the ibotenic acid-lesioned rat striatum

1984 • 302 citations

Glial cell line‐derived neurotrophic factor supports survival of injured midbrain dopaminergic neurons

1995 • 290 citations

Regional and Cell-Specific Expression of GDNF in Rat Brain

1993 • 272 citations

Ontogeny and distribution of glial cell line-derived neurotrophic factor (GDNF) mRNA in rat

1995 • 270 citations

Short-Term GDNF Treatment Provides Long-Term Rescue of Lesioned Nigral Dopaminergic Neurons in a Rat Model of Parkinson’s Disease

1996 • 258 citations

Retrograde axonal transport of glial cell line-derived neurotrophic factor in the adult nigrostriatal system suggests a trophic role in the adult.

1995 • 257 citations

Studies on Neuroprotective and Regenerative Effects of GDNF in a Partial Lesion Model of Parkinson's Disease

1997 • 243 citations

Glial cell line-derived neurotrophic factor augments midbrain dopaminergic circuits in vivo

1995 • 237 citations

Cellular expression of GDNF mRNA suggests multiple functions inside and outside the nervous system

1996 • 236 citations

Striatal grafts in rats with unilateral neostriatal lesions—III. Recovery from dopamine-dependent motor asymmetry and deficits in skilled paw reaching

1988 • 215 citations

Correspondence

1996 • 215 citations

Expression of GDNF mRNA in Rat and Human Nervous Tissue

1994 • 192 citations

Reversal of long-term locomotor abnormalities in the kainic acid model of huntington's disease by day 18 fetal striatal implants

1983 • 185 citations

Intrastriatal grafts derived from fetal striatal primordia. I. Phenotypy and modular organization

1989 • 169 citations

Neuronal GDNF Expression in the Adult Rat Nervous System Identified By In Situ Hybridization

1997 • 161 citations

Projection neurons in fetal striatal transplants are predominantly derived from the lateral ganglionic eminence

1995 • 158 citations

Connectivity of striatal grafts implanted into the ibotenic acid-lesioned striatum—III. Efferent projecting graft neurons and their relation to host afferents within the grafts

1989 • 147 citations

Increased proportion of acetylcholinesterase-rich zones and improved morphological integration in host striatum of fetal grafts derived from the lateral but not the medial ganglionic eminence

1993 • 145 citations

Localization of Glial Cell Line-derived Neurotrophic Factor (GDNF) mRNA in Embryonic Rat byIn SituHybridization

1996 • 131 citations

Development of a dopamine- and cyclic adenosine 3':5'-monophosphate- regulated phosphoprotein (DARPP-32) in the prenatal rat central nervous system, and its relationship to the arrival of presumptive dopaminergic innervation

1987 • 122 citations

Implants of Polymer-Encapsulated Genetically Modified Cells Releasing Glial Cell Line-Derived Neurotrophic Factor Improve Survival, Growth, and Function of Fetal Dopaminergic Grafts

1998 • 121 citations

Intrinsic Organization and Connectivity of Intrastriatal Striatal Transplants in Rats as Revealed by DARPP‐32 Immunohistochemistry: Specificity of Connections with the Lesioned Host Brain

1989 • 116 citations

Postnatal development of striatal dopamine function. I. An examination of D1 and D2 receptors, adenylate cyclase regulation and presynaptic dopamine markers

1990 • 106 citations

Glial cell line-derived neurotrophic factor improves survival of ventral mesencephalic grafts to the 6-hydroxydopamine lesioned striatum

1997 • 106 citations

Development of intrastriatal striatal grafts and their afferent innervation from the host

1991 • 97 citations

Glial cell line-derived neurotrophic factor attenuates behavioural deficits and regulates nigrostriatal dopaminergic and peptidergic markers in 6-hydroxydopamine-lesioned adult rats: comparison of intraventricular and intranigral delivery

1997 • 91 citations

GDNF triggers fiber outgrowth of fetal ventral mesencephalic grafts from nigra to striatum in 6-OHDA-lesioned rats

1996 • 85 citations

The Process of Reinnervation in the Dentate Gyrus of Adult Rats: Temporal Relationship between Changes in the Levels of Glial Fibrillary Acidic Protein (GFAP) and GFAP mRNA in Reactive Astrocytes

1993 • 82 citations

Neuronal organization of fetal striatal grafts in kainate- and sham- lesioned rat caudate nucleus: light- and electron-microscopic observations

1988 • 79 citations

Intracerebroventricular Glial Cell Line-Derived Neurotrophic Factor Improves Motor Function and Supports Nigrostriatal Dopamine Neurons in Bilaterally 6-Hydroxydopamine Lesioned Rats

1997 • 64 citations

GDNF: a cytokine at the interface of TGF-βs and neurotrophins

1996 • 58 citations

Embryonic mesencephalic and striatal co-grafts: Development of grafted dopamine neurons and functional recovery

1990 • 51 citations

Basic neural transplantation techniques. I. Dissociated cell suspension grafts of embryonic ventral mesencephalon in the adult rat brain

1997 • 47 citations

GDNF in a Bind with Known Orphan: Accessory Implicated in New Twist

1996 • 40 citations

Embryonic substantia nigra grafts innervate embryonic striatal co-grafts in preference to mature host striatum

1987 • 36 citations

Enhanced Efficacy of Nigral-Striatal Cotransplants in Bilaterally Dopamine-Depleted Rats: An Anatomical and Behavioral Analysis

1994 • 34 citations

Glial cell line-derived neurotrophic factor enhances survival and growth of prenatal and postnatal spinal cord transplants

1996 • 24 citations

Cortical stimulation induces fos expression in intrastriatal striatal grafts

1994 • 23 citations

Comparison between normal developing striatum and developing striatal grafts using drug-induced fos expression and neuron-specific enolase immunohistochemistry

1994 • 18 citations

Selective association of dopamine axons with their striatal target cells in vitro

1989 • 13 citations

Intrathalamic striatal grafts survive and affect circling behaviour in adult rats with excitotoxically lesioned striatum

1995 • 12 citations

GABAA receptor subunit expression in intrastriatal striatal grafts

1997 • 8 citations