Psychopharmacological implications of dopamine and dopamine antagonists: a critical evaluation of current evidence

Dementia Praecox or the Group of Schizophrenias

1951 • 4,409 citations

A PROPOSED MECHANISM OF EMOTION

1937 • 3,511 citations

Brain dopamine and the syndromes of Parkinson and Huntington Clinical, morphological and neurochemical correlations

1973 • 2,615 citations

Dopamine Receptor Binding Predicts Clinical and Pharmacological Potencies of Antischizophrenic Drugs

1976 • 2,224 citations

Verteilung Von Noradrenalin Und Dopamin (3-Hydroxytyramin) Im Gehirn Des Menschen Und Ihr Verhalten Bei Erkrankungen Des Extrapyramidalen Systems

1960 • 1,863 citations

Antipsychotic drug doses and neuroleptic/dopamine receptors

1976 • 1,623 citations

Aromatic Amino Acids and Modification of Parkinsonism

1967 • 1,464 citations

Advances in biochemical psychopharmacology

1970 • 1,186 citations

Psychosomatic Disease and the "Visceral Brain"

1949 • 1,163 citations

Dopamine-sensitive adenylate cyclase in caudate nucleus of rat brain, and its similarity to the “dopamine receptor”

1972 • 1,022 citations

Antipsychotic Drugs: Direct Correlation Between Clinical Potency and Presynaptic Action on Dopamine Neurons

1975 • 874 citations

Drugs, Neurotransmitters, and Schizophrenia

1974 • 832 citations

Some psychiatric implications of physiological studies on frontotemporal portion of limbic system (Visceral brain)

1952 • 764 citations

Brain receptors for antipsychotic drugs and dopamine: direct binding assays.

1975 • 695 citations

The Early Symptoms of Schizophrenia

1966 • 666 citations

On the Presence of 3-Hydroxytyramine in Brain

1958 • 632 citations

Activation: A Neuropsychological Dimension

1979 • 631 citations

The neurosciences. Third study program

1975 • 623 citations

Amphetamine Psychosis: A "Model" Schizophrenia Mediated by Catecholamines

1973 • 590 citations

[The L-3,4-dioxyphenylalanine (DOPA)-effect in Parkinson-akinesia].

1961 • 515 citations

Mesencephalic dopamine neurons projecting to neocortex

1974 • 503 citations

Dopaminergic Terminals in the Rat Cortex

1973 • 502 citations

Properties of [3H]haloperidol and [3H]dopamine binding associated with dopamine receptors in calf brain membranes.

1976 • 480 citations

The phenomenology of experimentally induced amphetamine psychosis--preliminary observations.

1970 • 475 citations

Advances in Neuroendocrinology.

1963 • 474 citations

Antischizophrenic Drugs and Brain Cholinergic Receptors

1974 • 474 citations

The psychological significance of the concept of "arousal" or "activation."

1957 • 471 citations

Dopamine-Sensitive Adenylate Cyclase in Mammalian Brain: A Possible Site of Action of Antipsychotic Drugs

1974 • 450 citations

Catecholamine uptake by synaptosomes in homogenates of rat brain: stereospecificity in different areas.

1969 • 445 citations

Amphetamine Psychosis

1957 • 429 citations

The neurochemistry of Parkinson's disease: effect of L-dopa therapy.

1975 • 386 citations

Anti-muscarinic properties of neuroleptics and drug-induced Parkinsonism

1974 • 382 citations

Morphological and Functional Aspects of Central Monoamine Neurons

1970 • 349 citations

Provocation of Schizophrenic Symptoms by Intravenous Administration of Methylphenidate

1973 • 310 citations

Biochemical demonstration of dopaminergic receptors in rat and human brain using [3H]spiroperidol

1977 • 298 citations

A comparison of the capacities of isomers of amphetamine, deoxypipradrol and methylphenidate to inhibit the uptake of tritiated catecholamines into rat cerebral cortex slices, synaptosomal preparations of rat cerebral cortex, hypothalamus and striatum and into adrenergic nerves of rabbit aorta.

1972 • 296 citations

Dopamine Nerve Terminals in the Rat Limbic Cortex: Aspects of the Dopamine Hypothesis of Schizophrenia

1974 • 290 citations

Dextroamphetamine

1972 • 274 citations

Anatomical and chemical studies of a nigro-neostriatal projection in the cat

1971 • 239 citations

The effect of drugs on arousal responses produced by electrical stimulation of the reticular formation of the brain

1958 • 232 citations

SCHIZOPHRENIA AND THE LIMBIC SYSTEM

1974 • 223 citations

Dopamine receptor binding in the corpus striatum of mammalian brain.

1975 • 221 citations

PITUITARY–ADRENAL SYSTEM HORMONES AND BEHAVIOR

1978 • 215 citations

Uptake of [3H]-catecholamines by homogenates of rat corpus striatum and cerebral cortex: Effects of amphetamine analogues

1973 • 215 citations

Catecholamine-containing neurones and electrical self-stimulation: 1. a review of some data

1972 • 199 citations

Propranolol in the Control of Schizophrenic Symptoms

1974 • 162 citations

Neostriatum and functions of prefrontal cortex.

1972 • 157 citations

On certain psychopharmacological and physiological differences between schizophrenic and normal persons

1965 • 118 citations

THE EFFECTS OF STRIATAL INJURY

1942 • 102 citations

Neurotransmitter receptor binding: regional distribution in human brain

1977 • 102 citations

Memory Disruption by Electrical Stimulation of Substantia Nigra, Pars Compacta

1973 • 101 citations

Dopamine and the pharmacology of schizophrenia: The state of the evidence

1974 • 99 citations

Beta-Adrenergic Receptor Blocking Drugs in Psychiatry

1974 • 99 citations

Perceptual capacity, functions of the corpus striatum and schizophrenia

1955 • 98 citations

Behavioral implications of dopaminergic neurons in the mesolimbic system.

1977 • 95 citations

Role of the tuberculum olfactorium in stereotyped behaviour induced by apomorphine in the rat

1972 • 90 citations

Evaluation of the biochemical effects produced in vivo by inhibitors of the three enzymes involved in norepinephrine biosynthesis.

1966 • 89 citations

Psychopathology And Psychopharmacology

1973 • 89 citations

Dopamine and norepinephrine uptake by rat brain synaptosomes: relative inhibitory potencies of 1- and d-amphetamine and amantadine.

1973 • 83 citations

Reticular Stimulation and Chlorpromazine: An Animal Model for Schizophrenic Overarousal

1969 • 77 citations

Parkinsonism induced by dopaminergic antagonists.

1975 • 73 citations

A neuronal basis for the alerting action of (+)‐amphetamine

1972 • 65 citations

Further studies on the mechanism of antipsychotic action: Potentiation by ?-methyltyrosine of thioridazine effects in chronic schizophrenics

1973 • 63 citations

Amphetamine psychosis. II. Theoretical implications.

1968 • 45 citations

The effect of drugs on the release of endogenous catecholamines into the perfusate of discrete brain areas of the cat in vivo

1975 • 35 citations

A two factor theory of schizophrenia

1974 • 35 citations

Discovery of the mesocortical dopaminergic system: some pharmacological and functional characteristics.

1977 • 34 citations

Model Systems in Biological Psychiatry

1976 • 31 citations

On the roles of dopamine and noradrenaline in animal behaviour

1974 • 23 citations

Actions of dopaminergic antagonists in the striatum.

1975 • 22 citations

Amphetamine Psychosis: II. Theoretical Implications

1969 • 22 citations

Permanent learning deficit associated with lesions in the caudate nuclei.

1963 • 21 citations

Muscarinic cholinergic receptor binding: Influence of pimozide and chlorpromazine metabolites

1976 • 20 citations

RÔLE OF THE NEOSTRIATUM

1941 • 19 citations

The Pharmacology of Psychotherapeutic Drugs

1969 • 19 citations

The Pharmacology of Psychotherapeutic Drugs

1969 • 19 citations

Interaction of Low-Dose Amphetamine Use with Schizophrenia in Outpatients: Three Case Reports

1974 • 19 citations

Pharmacological Aspects of Neuroendocrine Integration

1972 • 17 citations

Labyrinthine Disregard after Removal of the Caudate.

1940 • 14 citations

A REVIEW OF SOME IMPORTANT STUDIES OF SCHIZOPHRENIC THOUGHT DISORDERS AND THEIR IMPLICATIONS

1973 • 7 citations

Discussion

1974 • 2 citations

Deleted Work

1955 • 0 citations