Mitochondrial Genotype Segregation During Preimplantation Development in Mouse Heteroplasmic Embryos

Rapid evolution of animal mitochondrial DNA.

1979 • 3,420 citations

Sequence and gene organization of mouse mitochondrial DNA

1981 • 1,712 citations

An improved culture medium supports development of random-bred 1-cell mouse embryos in vitro

1989 • 1,119 citations

Paternal inheritance of mitochondrial DNA in mice

1991 • 674 citations

Nuclear Transplantation in the Mouse Embryo by Microsurgery and Cell Fusion

1983 • 581 citations

Random genetic drift in the female germline explains the rapid segregation of mammalian mitochondrial DNA

1996 • 580 citations

Amounts of mitochondrial DNA and abundance of some mitochondrial gene transcripts in early mouse embryos

1987 • 435 citations

The Clinical Characteristics of Pedigrees of Leber's Hereditary Optic Neuropathy With the 11778 Mutation

1991 • 390 citations

In situ localization of mitochondrial DNA replication in intact mammalian cells.

1996 • 249 citations

Rapid segregation of heteroplasmic bovine mitodiondria

1989 • 235 citations

Achievements and perspectives of mitochondrial research

1985 • 210 citations

Maternal inheritance of mitochondrial DNA during backcrossing of two species of mice

1985 • 198 citations

Different cellular backgrounds confer a marked advantage to either mutant or wild-type mitochondrial genomes.

1995 • 194 citations

Replacement of bovine mitochondrial DNA by a sequence variant within one generation.

1991 • 178 citations

Mitochondrial Genotype Segregation in a Mouse Heteroplasmic Lineage Produced by Embryonic Karyoplast Transplantation

1997 • 175 citations

Homopolymeric tract heteroplasmy in mtDNA from tissues and single oocytes: support for a genetic bottleneck.

1997 • 156 citations

Allocation of cells to inner cell mass and trophectoderm lineages in preimplantation mouse embryos

1982 • 150 citations

Polarization of mitochondria in the unfertilized mouse oocyte

1995 • 150 citations

Origins of Laboratory Mice Deduced from Restriction Patterns of Mitochondrial DNA

1982 • 135 citations

Mitochondrial gene segregation in mammals: is the bottleneck always narrow?

1992 • 134 citations

Cytoplasmic inheritance and its effects on development and performance.

1993 • 124 citations

Mitochondrial DNA in the mouse preimplantation embryo

1988 • 81 citations

Sequential observation of mitochondrial distribution in mouse oocytes and embryos

1993 • 49 citations

Mitochondrial biogenesis in early mouse embryos: Expression of the mRNAs for subunits IV, Vb, and VIIc of cytochrome c oxidase and subunit 9 (P1) of H⁺‐ATP synthase

1995 • 43 citations

[31]Construction of heteroplasmic mice containing two mitochondrial DNA genotypes by micromanipulation of single-cell embryos

1996 • 40 citations

Sperm chromosome analysis of a man heterozygous for a pericentric inversion of chromosome 20

1992 • 33 citations

Tissue segregation of a heteroplasmic mtDNA mutation in MERRF (Myoclonic epilepsy with ragged red fibers) encephalomyopathy

1992 • 32 citations

A near homoplasmic T8993G mtDNA mutation in a patient with atypic Leigh syndrome not present in the mother's tissues

1997 • 31 citations

Heterogeneous mitochondria dna introduced by nuclear transfer influences the developmental ability of mouse embryos in vitro

1997 • 16 citations

Homology between mitochondriogenesis in the avian and amphibian oocyte

1995 • 16 citations