Inhibition of Cytokine-Induced NF-κB Activation by Adenovirus-Mediated Expression of a NF-κB Super-Repressor Prevents β-Cell Apoptosis

Analysis of nitrate, nitrite, and [15N]nitrate in biological fluids

1982 • 11,668 citations

Activators and Target Genes of Rel/NF-кB Transcription Factors

2003 • 3,164 citations

Control of IκB-α Proteolysis by Site-Specific, Signal-Induced Phosphorylation

1995 • 1,443 citations

Control of apoptosis by Rel/NF-κB transcription factors

1999 • 1,204 citations

How NF-κB is activated: the role of the IκB kinase (IKK) complex

1999 • 1,133 citations

The role of interleukin-1 in the pathogenesis of IDDM

1996 • 528 citations

Is Green Fluorescent Protein Toxic to the Living Cells?

1999 • 513 citations

An update on cytokines in the pathogenesis of insulin-dependent diabetes mellitus

1998 • 437 citations

A New in Vitro Model for the Study of Pancreatic A and B Cells*

1985 • 345 citations

Cytokines Induce Deoxyribonucleic Acid Strand Breaks and Apoptosis in Human Pancreatic Islet Cells*

1997 • 302 citations

Glucose promotes survival of rat pancreatic beta cells by activating synthesis of proteins which suppress a constitutive apoptotic program.

1996 • 279 citations

Nitric Oxide Primes Pancreatic β Cells for Fas-mediated Destruction in Insulin-dependent Diabetes Mellitus

1997 • 242 citations

Identification of Novel Cytokine-Induced Genes in Pancreatic β-Cells by High-Density Oligonucleotide Arrays

2001 • 231 citations

Regulation by cytokines of the inducible nitric oxide synthase promoter in insulin-producing cells

1998 • 219 citations

Cytokines induce apoptosis in beta-cells isolated from mice lacking the inducible isoform of nitric oxide synthase (iNOS-/-).

2000 • 211 citations

Protection of Human Islets from the Effects of Interleukin-1β by Adenoviral Gene Transfer of an IκB Repressor

2000 • 210 citations

Inhibition of NF?B in activated rat hepatic stellate cells by proteasome inhibitors and an I?B super-repressor

1998 • 178 citations

beta-cell apoptosis and defense mechanisms: lessons from type 1 diabetes.

2001 • 175 citations

Fas and Fas ligand expression in inflamed islets in pancreas sections of patients with recent-onset Type I diabetes mellitus

1999 • 160 citations

IL-1α, IL-1β, and IFN-γ mark β cells for Fas-dependent destruction by diabetogenic CD4+ T lymphocytes

2000 • 129 citations

Beta-cell destruction in NOD mice correlates with Fas (CD95) expression on beta-cells and proinflammatory cytokine expression in islets.

1999 • 107 citations

Effect of nutrients, hormones and serum on survival of rat islet beta cells in culture

1994 • 105 citations

Is there a role for nitric oxide in β-cell dysfunction and damage in IDDM?

1997 • 91 citations

Activation of extracellular signal-regulated kinase (ERK)1/2 contributes to cytokine-induced apoptosis in purified rat pancreatic beta-cells.

2000 • 87 citations

Cytokine Induction of Fas Gene Expression in Insulin-Producing Cells Requires the Transcription Factors NF-κB and C/EBP

2001 • 74 citations

Adult human pancreatic duct and islet cells exhibit similarities in expression and differences in phosphorylation and complex formation of the homeodomain protein Ipf-1.

2000 • 67 citations

NF-κB Is Required for Cytokine-Induced Manganese Superoxide Dismutase Expression in Insulin-Producing Cells¹

2000 • 61 citations

Identification of IL-1β-induced messenger RNAs in rat pancreatic beta cells by differential display of messenger RNA

1999 • 52 citations

The role of interferon regulatory factor-1 in cytokine-induced mRNA expression and cell death in murine pancreatic beta-cells.

1999 • 49 citations

Genotoxic Agents Increase Expression of Growth Arrest and DNA Damage–Inducible Genes gadd 153 and gadd 45 in Rat Pancreatic Islets

1993 • 48 citations

Pyrrolidine Dithiocarbamate Prevents IL-1-Induced Nitric Oxide Synthase mRNA, but Not Superoxide Dismutase mRNA, in Insulin Producing Cells

1995 • 46 citations

Interleukin-1β Induced Activation of NF-κB in Insulin-Producing RINm5F Cells Is Prevented by the Protease Inhibitor Nα-p-Tosyl-L-Lysine Chloromethylketone

1994 • 44 citations

Intercellular Differences in Interleukin 1β-Induced Suppression of Insulin Synthesis and Stimulation of Noninsulin Protein Synthesis by Rat Pancreatic β-Cells*

1998 • 42 citations

Inhibition of proinllammatory molecule expression by adenovirus-mediated expression of an NFkB super repressor in activated hepatic stellate cells

1998 • 21 citations

Islet expression of perforin, Fas/Apo-1 and interleukin-1 converting enzyme (ICE) in non-obese diabetic (NOD) mice

1998 • 21 citations