Phase II evaluation of mitozolomide in ovarian cancer

Antitumour imidazotetrazines. 1. Synthesis and chemistry of 8-carbamoyl-3-(2-chloroethyl)imidazo[5,1-d]-1,2,3,5-tetrazin-4(3H)-one, a novel broad-spectrum antitumor agent

1984 • 212 citations

Common Epithelial Cancer of the Ovary

1985 • 208 citations

Experimental antitumor activity against murine tumor model systems of 8-carbamoyl-3-(2-chloroethyl)imidazo[5,1-d]-1,2,3,5-tetrazin-4(3 H)-one (mitozolomide), a novel broad-spectrum agent.

1985 • 51 citations

Phase I clinical trial of mitozolomide.

1985 • 50 citations

Mitozolomide activity on human cancer cells in vitro

1986 • 13 citations