Isolation of functional human regulatory T cells (Treg) from the peripheral blood based on the CD39 expression

CD127 expression inversely correlates with FoxP3 and suppressive function of human CD4+ T reg cells

2006 • 2,516 citations

Adenosine generation catalyzed by CD39 and CD73 expressed on regulatory T cells mediates immune suppression

2007 • 2,215 citations

A function for interleukin 2 in Foxp3-expressing regulatory T cells

2005 • 1,744 citations

Prevalence of Regulatory T Cells Is Increased in Peripheral Blood and Tumor Microenvironment of Patients with Pancreas or Breast Adenocarcinoma

2002 • 1,454 citations

Autoimmune disease as a consequence of developmental abnormality of a T cell subpopulation.

1996 • 1,335 citations

Identification and Functional Characterization of Human Cd4+Cd25+ T Cells with Regulatory Properties Isolated from Peripheral Blood

2001 • 1,293 citations

Expression of ectonucleotidase CD39 by Foxp3+ Treg cells: hydrolysis of extracellular ATP and immune suppression

2007 • 1,181 citations

Ex Vivo Isolation and Characterization of Cd4+Cd25+ T Cells with Regulatory Properties from Human Blood

2001 • 1,168 citations

Regulatory CD4(+)CD25(+) T cells in tumors from patients with early-stage non-small cell lung cancer and late-stage ovarian cancer.

2001 • 1,126 citations

Human Cd25+Cd4+ T Regulatory Cells Suppress Naive and Memory T Cell Proliferation and Can Be Expanded in Vitro without Loss of Function

2001 • 1,008 citations

FOXP3: Of Mice and Men

2005 • 929 citations

The E-NTPDase family of ectonucleotidases: Structure function relationships and pathophysiological significance

2006 • 880 citations

Organ-specific autoimmune diseases induced in mice by elimination of T cell subset. I. Evidence for the active participation of T cells in natural self-tolerance; deficit of a T cell subset as a possible cause of autoimmune disease.

1985 • 721 citations

A Unique Subset of CD4+CD25highFoxp3+ T Cells Secreting Interleukin-10 and Transforming Growth Factor-β1 Mediates Suppression in the Tumor Microenvironment

2007 • 429 citations

Expression of FOXP3 mRNA is not confined to CD4+CD25+ T regulatory cells in humans

2004 • 415 citations

Regulatory T cells – a brief history and perspective

2007 • 351 citations

Human CD4+ regulatory T cells express lower levels of the IL-7 receptor alpha chain (CD127), allowing consistent identification and sorting of live cells

2006 • 290 citations

The Frequency and Suppressor Function of CD4+CD25highFoxp3+ T Cells in the Circulation of Patients with Squamous Cell Carcinoma of the Head and Neck

2007 • 273 citations

Regulatory T cells and treatment of cancer

2008 • 253 citations

Foxp3 expression in human cancer cells

2008 • 209 citations

Regulatory T Cells in Immunologic Self-Tolerance and Autoimmune Disease

2005 • 198 citations

Is FOXP3 a bona fide marker for human regulatory T cells?

2008 • 168 citations

The regulation of Foxp3 expression in regulatory CD4⁺CD25⁺T cells: Multiple pathways on the road

2007 • 161 citations

Function of the IL-2R for Thymic and Peripheral CD4+CD25+ Foxp3+ T Regulatory Cells

2007 • 156 citations

FOXP3 expression accurately defines the population of intratumoral regulatory T cells that selectively accumulate in metastatic melanoma lesions

2008 • 140 citations

Clinical Grade Treg: GMP Isolation, Improvement of Purity by CD127pos Depletion, Treg Expansion, and Treg Cryopreservation

2008 • 122 citations

Regulatory T cells in the past and for the future

2008 • 86 citations

CD4+CD25+Foxp3+ regulatory T cells: from basic research to potential therapeutic use

2007 • 51 citations

Induction of Tolerance by Adoptive Transfer of Treg Cells

2007 • 33 citations

Adenosine and anergy

2007 • 25 citations

The biology and therapeutic potential of natural regulatory T-cells in the bone marrow transplant setting

2008 • 20 citations

Isolation, Flow Cytometric Analysis, and Suppression Assay of CD4+ CD25+ T-Regulatory Cells

2008 • 3 citations